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The map label for this gene is aer [H]

Identifier: 22125699

GI number: 22125699

Start: 1984630

End: 1986267

Strand: Reverse

Name: aer [H]

Synonym: y1805

Alternate gene names: 22125699

Gene position: 1986267-1984630 (Counterclockwise)

Preceding gene: 22125700

Following gene: 22125698

Centisome position: 43.17

GC content: 49.94

Gene sequence:

>1638_bases
TTGAAGTATAACGGGTCTATTGACTACCAGGGATCTCCTCCCTTTACTGAGGTTAATATGAGAGTTAACAAACCTGTCAG
CCGGCAGGAGTATCCCATTGAGCGCGATATCACCTTGCAGTCCACCACTGATATTCATGGAAATATTGCTTACGCTAATG
CTGCTTTTGTTCGTGCCAGTGGCTTTGAATATCAAGAGTTGCAGGGTCAACCTCACAATATGGTAAGGCACCCCGATATG
CCACCCGCGGCTTTTGCTGATATGTGGCAAACATTGAATGCCGGTCTTTCTTGGTCTTCATTGGTGAAGAATCGCCGTAA
AAATGGAGATTATTACTGGGTCCGGGCTAATGCGACGCCACTGCGCCATAATGGCCGTTTAACCGGTTATATTTCGGTAC
GTATTGCGCCAACTCGCGATGAGGTAAAACAAGCTGAAGCATTGTATACCGATTTCAACACCGGTAAGGCAAAACGGCGG
CATATTGCCTTGTATCGTGGGCTGATCGTGCGCACGGGGTGGCTCTCCCCACTTTCTTTGTTCCAAACTTTACCATTACG
CTGGCGCCTGCGGAGTGCCTTGCTAAGTTCCGCCATCATTCCAACCGCCGCCGCCAGTGTGATGGAGGTAGCGGGTCAAC
CTCTCTTGATTCTCGGCTCGGTGGCATTGACCTGGAGCGTATTGGCTTCACTGTGGTTGGAGCGGCAGATTGCCCGCCCC
ATCGCGGCTATTTTGCAACAGGCGCAGGACGTTTCCTCCGGAGAAGCAGGCGATTATGTACAACTAAATCGTGTCGATGA
AATCGGTTATTTAATGCGTAGCGTCAATCAACTCGGCCTGAACCTACGTTCTTTAACCGATGATGTCAGTGGTCAGGTTG
ATGGGATTAATACCGCCAGCAACGAAATTGCTGCTGGCAATCGCGAACTAAAAGTACGAACCGAACAAGCAACCGATAAT
CTGCAACACATTGTCAGTGCCACAGAACAATTAGCTGCGACAGTGCAGAACAGCGCTAACAGTGCCAATGAAACAACATC
ACTCGCCGAAATGAGCAGCCATGCCGCAGAAAAAGGCAGCGAGCTCATGCACCAAGTCATTGAAACTATGGGCACTATCA
ATGACTCCAGCCATCGCATTGTAGATATTATCAGTGTGATTGAAGGCATTGCTTTTCAGACCAATATTCTGGCACTCAAC
GCGGCCGTAGAAGCGGCCCGGGCGGGTGAACAAGGTCGTGGATTTGCCGTAGTTGCCAGCGAGGTACGCCATTTGGCACA
ACGTTCGTCAACCGCAGCAAAAGAGATTAAACATTTAATTGAGACCAGTGTAGAGCGGGTACGTGACGGAAGTACTTTGG
TGCAAAGTGCCGGTGCCACTATGGACAATATTGTCAAACAGGCAAGCCAGGTCTCTACGTTGATCAGTGAAATCAGCACC
TCGACTCATGAACAGACACAGGCCCTTGGCCAAATCCGGCAATCGATCAGTCGGCTAGATCAAATGACTTACCAGAATGC
CGCGATGGTTGAGCAATATGCTGGCGCGGCAGAAGAACTGGCACATCGGACATTGCGACTAACCGCGGCGGTCCGTATTT
ACCGCCCATTGAATAACGTAGGAAAGTTAAGGGATTAG

Upstream 100 bases:

>100_bases
CTCGCAGGATAAGGCTCATTAATCTCGATAAGCTTACTTATTTAAGGTCAACGACCAGTAAGTAATTCGGATTATTGAAC
GTAGCCAACGCACAGGTAAC

Downstream 100 bases:

>100_bases
ACAGAATCACCGCATTATCTGTTACCCCTATCCCGACTGGGAGGTGATTTATCATAGCAATAATCTAAAACCTCGCTATA
GTGGGTAGGTGGTTATCCAA

Product: aerotaxis sensor receptor, flavoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MKYNGSIDYQGSPPFTEVNMRVNKPVSRQEYPIERDITLQSTTDIHGNIAYANAAFVRASGFEYQELQGQPHNMVRHPDM
PPAAFADMWQTLNAGLSWSSLVKNRRKNGDYYWVRANATPLRHNGRLTGYISVRIAPTRDEVKQAEALYTDFNTGKAKRR
HIALYRGLIVRTGWLSPLSLFQTLPLRWRLRSALLSSAIIPTAAASVMEVAGQPLLILGSVALTWSVLASLWLERQIARP
IAAILQQAQDVSSGEAGDYVQLNRVDEIGYLMRSVNQLGLNLRSLTDDVSGQVDGINTASNEIAAGNRELKVRTEQATDN
LQHIVSATEQLAATVQNSANSANETTSLAEMSSHAAEKGSELMHQVIETMGTINDSSHRIVDIISVIEGIAFQTNILALN
AAVEAARAGEQGRGFAVVASEVRHLAQRSSTAAKEIKHLIETSVERVRDGSTLVQSAGATMDNIVKQASQVSTLISEIST
STHEQTQALGQIRQSISRLDQMTYQNAAMVEQYAGAAEELAHRTLRLTAAVRIYRPLNNVGKLRD

Sequences:

>Translated_545_residues
MKYNGSIDYQGSPPFTEVNMRVNKPVSRQEYPIERDITLQSTTDIHGNIAYANAAFVRASGFEYQELQGQPHNMVRHPDM
PPAAFADMWQTLNAGLSWSSLVKNRRKNGDYYWVRANATPLRHNGRLTGYISVRIAPTRDEVKQAEALYTDFNTGKAKRR
HIALYRGLIVRTGWLSPLSLFQTLPLRWRLRSALLSSAIIPTAAASVMEVAGQPLLILGSVALTWSVLASLWLERQIARP
IAAILQQAQDVSSGEAGDYVQLNRVDEIGYLMRSVNQLGLNLRSLTDDVSGQVDGINTASNEIAAGNRELKVRTEQATDN
LQHIVSATEQLAATVQNSANSANETTSLAEMSSHAAEKGSELMHQVIETMGTINDSSHRIVDIISVIEGIAFQTNILALN
AAVEAARAGEQGRGFAVVASEVRHLAQRSSTAAKEIKHLIETSVERVRDGSTLVQSAGATMDNIVKQASQVSTLISEIST
STHEQTQALGQIRQSISRLDQMTYQNAAMVEQYAGAAEELAHRTLRLTAAVRIYRPLNNVGKLRD
>Mature_545_residues
MKYNGSIDYQGSPPFTEVNMRVNKPVSRQEYPIERDITLQSTTDIHGNIAYANAAFVRASGFEYQELQGQPHNMVRHPDM
PPAAFADMWQTLNAGLSWSSLVKNRRKNGDYYWVRANATPLRHNGRLTGYISVRIAPTRDEVKQAEALYTDFNTGKAKRR
HIALYRGLIVRTGWLSPLSLFQTLPLRWRLRSALLSSAIIPTAAASVMEVAGQPLLILGSVALTWSVLASLWLERQIARP
IAAILQQAQDVSSGEAGDYVQLNRVDEIGYLMRSVNQLGLNLRSLTDDVSGQVDGINTASNEIAAGNRELKVRTEQATDN
LQHIVSATEQLAATVQNSANSANETTSLAEMSSHAAEKGSELMHQVIETMGTINDSSHRIVDIISVIEGIAFQTNILALN
AAVEAARAGEQGRGFAVVASEVRHLAQRSSTAAKEIKHLIETSVERVRDGSTLVQSAGATMDNIVKQASQVSTLISEIST
STHEQTQALGQIRQSISRLDQMTYQNAAMVEQYAGAAEELAHRTLRLTAAVRIYRPLNNVGKLRD

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=508, Percent_Identity=47.4409448818898, Blast_Score=451, Evalue=1e-128,
Organism=Escherichia coli, GI1788195, Length=314, Percent_Identity=46.4968152866242, Blast_Score=244, Evalue=9e-66,
Organism=Escherichia coli, GI2367378, Length=322, Percent_Identity=42.2360248447205, Blast_Score=228, Evalue=9e-61,
Organism=Escherichia coli, GI1788194, Length=303, Percent_Identity=43.5643564356436, Blast_Score=224, Evalue=8e-60,
Organism=Escherichia coli, GI1787690, Length=323, Percent_Identity=41.1764705882353, Blast_Score=221, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 59809; Mature: 59809

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYNGSIDYQGSPPFTEVNMRVNKPVSRQEYPIERDITLQSTTDIHGNIAYANAAFVRAS
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCEEEECEEEEEEC
GFEYQELQGQPHNMVRHPDMPPAAFADMWQTLNAGLSWSSLVKNRRKNGDYYWVRANATP
CCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCC
LRHNGRLTGYISVRIAPTRDEVKQAEALYTDFNTGKAKRRHIALYRGLIVRTGWLSPLSL
CCCCCEEEEEEEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHH
FQTLPLRWRLRSALLSSAIIPTAAASVMEVAGQPLLILGSVALTWSVLASLWLERQIARP
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
IAAILQQAQDVSSGEAGDYVQLNRVDEIGYLMRSVNQLGLNLRSLTDDVSGQVDGINTAS
HHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCC
NEIAAGNRELKVRTEQATDNLQHIVSATEQLAATVQNSANSANETTSLAEMSSHAAEKGS
CHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
ELMHQVIETMGTINDSSHRIVDIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAS
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCHHHHHH
EVRHLAQRSSTAAKEIKHLIETSVERVRDGSTLVQSAGATMDNIVKQASQVSTLISEIST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
STHEQTQALGQIRQSISRLDQMTYQNAAMVEQYAGAAEELAHRTLRLTAAVRIYRPLNNV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
GKLRD
CCCCC
>Mature Secondary Structure
MKYNGSIDYQGSPPFTEVNMRVNKPVSRQEYPIERDITLQSTTDIHGNIAYANAAFVRAS
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCEEEECEEEEEEC
GFEYQELQGQPHNMVRHPDMPPAAFADMWQTLNAGLSWSSLVKNRRKNGDYYWVRANATP
CCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCC
LRHNGRLTGYISVRIAPTRDEVKQAEALYTDFNTGKAKRRHIALYRGLIVRTGWLSPLSL
CCCCCEEEEEEEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHH
FQTLPLRWRLRSALLSSAIIPTAAASVMEVAGQPLLILGSVALTWSVLASLWLERQIARP
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
IAAILQQAQDVSSGEAGDYVQLNRVDEIGYLMRSVNQLGLNLRSLTDDVSGQVDGINTAS
HHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCC
NEIAAGNRELKVRTEQATDNLQHIVSATEQLAATVQNSANSANETTSLAEMSSHAAEKGS
CHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
ELMHQVIETMGTINDSSHRIVDIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAS
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCHHHHHH
EVRHLAQRSSTAAKEIKHLIETSVERVRDGSTLVQSAGATMDNIVKQASQVSTLISEIST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
STHEQTQALGQIRQSISRLDQMTYQNAAMVEQYAGAAEELAHRTLRLTAAVRIYRPLNNV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
GKLRD
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]