Click here to switch to the map view.

The map label for this gene is pepT [H]

Identifier: 22125685

GI number: 22125685

Start: 1971063

End: 1972328

Strand: Direct

Name: pepT [H]

Synonym: y1791

Alternate gene names: 22125685

Gene position: 1971063-1972328 (Clockwise)

Preceding gene: 22125684

Following gene: 22125696

Centisome position: 42.84

GC content: 45.18

Gene sequence:

>1266_bases
ATGTTATTCACTATTATGAGGGTGGGAACCATGGACAAATTACTCGACCGATTTTTCAACTATGTTTCTTTTGATACACA
AGCAAAAGCCAATGTAAAATCTGTGCCGAGCACTCAGGGACAGCGCAAGCTTGCTCAGGCGTTGCAACAGGAATTATTGA
CGTTGGGCTTTTCCCACGTCACCTTGAGCGATCATGGTTGCGTGATGGCAACATTGCCGGCAAATGTCTCCTGGCCGGTC
CCCACGATTGGCTTTATTGCCCATCTGGACACCTCACCAGATTTTTCAGGTAAAAATGTTAATCCACAGATAGTGGAGAA
CTACCGTGGTGGTGATATTGCGTTAGGTATTGGTGATGAGGTTTTATCTCCTGTTATGTTCCCGGTATTACATCAATTAC
TTGGACATACCTTGATCACGACTGATGGTAAAACCCTGTTAGGGGCGGATGATAAAGCGGGTATTGCTGAAATCATTACC
GCTATGGTGCGCTTAAAGCACCGTAATGTCCCCCATGGGGATATTCGTATTGCCTTCACACCGGATGAAGAAGTGGGTAA
GGGGGCTCAGTTTTTTAATGTGGCAGAGTTTGATGCACAGTGGGCTTATACCGTTGATGGTGGCGGCATTGGTGAATTAG
AGTTTGAAAATTTCAATGCAGCATCGGTGGCAATAAAGATCGTCGGCAATAATGTTCATCCAGGCAGTGCTAAGGGCGTC
ATGGTTAATGCGTTGTCGCTGGCAACCCGTTACCATCAAGAGTTGCCAGTAGATGAAACCCCAGAGTGTACTGAGGGTTA
CGACGGTTTCTATCATCTGCAAAGTATTAAAGGCACGGTTGAACGCGCTGAGATGCACTACATTGTTCGAGATTTCAATC
GCGATAGCTTTGAAGCGCGGAAGAAGAATATGGTGGATATCGCCAAGCGGGTTGGTAAAGGTTTACATCGTGATTGTTAT
ATCGAAATTGTTATCGATGACAGCTATTACAATATGCGTGAGCAGATTATTAAGCACCCGCACATTATCGAATTAGCCCA
ACAGGCCATGCTTGACTGTGATATTACTCCGATTATGAAGCCAATTCGTGGTGGTACCGATGGTGCACAACTCTCTTTTA
AAGGGTTACCTTGCCCGAATATTTTTACCGGAGGCTATAATTACCACGGTAAACATGAGTTTATTACGCTGGAAGGGATG
GAAAAAGCGGTTGCAGTCATTATGCGAATTTCTGAGCTGACCGCCAAGCGGGCTAAAGAATCATAA

Upstream 100 bases:

>100_bases
CTCATATTCCTGAGTACCTCGTCACTACCTCTTATTATTCTGGCTTAAGTTTATCTAAAGCTGACCTGACGCAATATTTG
ATCATGATCACTTCCCCATA

Downstream 100 bases:

>100_bases
GCTGAACGATAGAGAGAAACGCCCCGAAAAGGGGCGTTTGAGGTTATTGACAAAGTGCCCATAGCGGAGTGAATAGGCAG
CAAGTAAAGATGCTGTAAAC

Product: peptidase T

Products: NA

Alternate protein names: Aminotripeptidase; Tripeptidase; Tripeptide aminopeptidase [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MLFTIMRVGTMDKLLDRFFNYVSFDTQAKANVKSVPSTQGQRKLAQALQQELLTLGFSHVTLSDHGCVMATLPANVSWPV
PTIGFIAHLDTSPDFSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGHTLITTDGKTLLGADDKAGIAEIIT
AMVRLKHRNVPHGDIRIAFTPDEEVGKGAQFFNVAEFDAQWAYTVDGGGIGELEFENFNAASVAIKIVGNNVHPGSAKGV
MVNALSLATRYHQELPVDETPECTEGYDGFYHLQSIKGTVERAEMHYIVRDFNRDSFEARKKNMVDIAKRVGKGLHRDCY
IEIVIDDSYYNMREQIIKHPHIIELAQQAMLDCDITPIMKPIRGGTDGAQLSFKGLPCPNIFTGGYNYHGKHEFITLEGM
EKAVAVIMRISELTAKRAKES

Sequences:

>Translated_421_residues
MLFTIMRVGTMDKLLDRFFNYVSFDTQAKANVKSVPSTQGQRKLAQALQQELLTLGFSHVTLSDHGCVMATLPANVSWPV
PTIGFIAHLDTSPDFSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGHTLITTDGKTLLGADDKAGIAEIIT
AMVRLKHRNVPHGDIRIAFTPDEEVGKGAQFFNVAEFDAQWAYTVDGGGIGELEFENFNAASVAIKIVGNNVHPGSAKGV
MVNALSLATRYHQELPVDETPECTEGYDGFYHLQSIKGTVERAEMHYIVRDFNRDSFEARKKNMVDIAKRVGKGLHRDCY
IEIVIDDSYYNMREQIIKHPHIIELAQQAMLDCDITPIMKPIRGGTDGAQLSFKGLPCPNIFTGGYNYHGKHEFITLEGM
EKAVAVIMRISELTAKRAKES
>Mature_421_residues
MLFTIMRVGTMDKLLDRFFNYVSFDTQAKANVKSVPSTQGQRKLAQALQQELLTLGFSHVTLSDHGCVMATLPANVSWPV
PTIGFIAHLDTSPDFSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGHTLITTDGKTLLGADDKAGIAEIIT
AMVRLKHRNVPHGDIRIAFTPDEEVGKGAQFFNVAEFDAQWAYTVDGGGIGELEFENFNAASVAIKIVGNNVHPGSAKGV
MVNALSLATRYHQELPVDETPECTEGYDGFYHLQSIKGTVERAEMHYIVRDFNRDSFEARKKNMVDIAKRVGKGLHRDCY
IEIVIDDSYYNMREQIIKHPHIIELAQQAMLDCDITPIMKPIRGGTDGAQLSFKGLPCPNIFTGGYNYHGKHEFITLEGM
EKAVAVIMRISELTAKRAKES

Specific function: Cleaves the N-terminal amino acid of tripeptides [H]

COG id: COG2195

COG function: function code E; Di- and tripeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20B family [H]

Homologues:

Organism=Escherichia coli, GI1787372, Length=407, Percent_Identity=76.9041769041769, Blast_Score=676, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR010161 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.11.4 [H]

Molecular weight: Translated: 46538; Mature: 46538

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFTIMRVGTMDKLLDRFFNYVSFDTQAKANVKSVPSTQGQRKLAQALQQELLTLGFSHV
CEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
TLSDHGCVMATLPANVSWPVPTIGFIAHLDTSPDFSGKNVNPQIVENYRGGDIALGIGDE
EECCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCEEEEECCHH
VLSPVMFPVLHQLLGHTLITTDGKTLLGADDKAGIAEIITAMVRLKHRNVPHGDIRIAFT
HHHHHHHHHHHHHHCCEEEECCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEC
PDEEVGKGAQFFNVAEFDAQWAYTVDGGGIGELEFENFNAASVAIKIVGNNVHPGSAKGV
CCHHHCCCCCEEEEEECCCEEEEEECCCCCCCEEECCCCCEEEEEEEEECCCCCCCCCCH
MVNALSLATRYHQELPVDETPECTEGYDGFYHLQSIKGTVERAEMHYIVRDFNRDSFEAR
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHH
KKNMVDIAKRVGKGLHRDCYIEIVIDDSYYNMREQIIKHPHIIELAQQAMLDCDITPIMK
HHHHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHH
PIRGGTDGAQLSFKGLPCPNIFTGGYNYHGKHEFITLEGMEKAVAVIMRISELTAKRAKE
HHCCCCCCCEEEECCCCCCCEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCC
S
C
>Mature Secondary Structure
MLFTIMRVGTMDKLLDRFFNYVSFDTQAKANVKSVPSTQGQRKLAQALQQELLTLGFSHV
CEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
TLSDHGCVMATLPANVSWPVPTIGFIAHLDTSPDFSGKNVNPQIVENYRGGDIALGIGDE
EECCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCEEEEECCHH
VLSPVMFPVLHQLLGHTLITTDGKTLLGADDKAGIAEIITAMVRLKHRNVPHGDIRIAFT
HHHHHHHHHHHHHHCCEEEECCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEC
PDEEVGKGAQFFNVAEFDAQWAYTVDGGGIGELEFENFNAASVAIKIVGNNVHPGSAKGV
CCHHHCCCCCEEEEEECCCEEEEEECCCCCCCEEECCCCCEEEEEEEEECCCCCCCCCCH
MVNALSLATRYHQELPVDETPECTEGYDGFYHLQSIKGTVERAEMHYIVRDFNRDSFEAR
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHH
KKNMVDIAKRVGKGLHRDCYIEIVIDDSYYNMREQIIKHPHIIELAQQAMLDCDITPIMK
HHHHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHH
PIRGGTDGAQLSFKGLPCPNIFTGGYNYHGKHEFITLEGMEKAVAVIMRISELTAKRAKE
HHCCCCCCCEEEECCCCCCCEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA