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The map label for this gene is ccmB [H]

Identifier: 22125463

GI number: 22125463

Start: 1735641

End: 1736327

Strand: Direct

Name: ccmB [H]

Synonym: y1568

Alternate gene names: 22125463

Gene position: 1735641-1736327 (Clockwise)

Preceding gene: 22125462

Following gene: 22125464

Centisome position: 37.73

GC content: 51.97

Gene sequence:

>687_bases
TTGTTTAGCCAACACGCAGGAGAAGTCATGTTTATCAGCGTGTTGCGCCGTGAATTAAAAATAGCCTTTAGAAAAGGTGC
GGAAATCGTTAACCCGCTGTGGTTCTTTTTGATCGTTATTACGCTGTTCCCATTGGGGATAGGCCCAGAGCCACAATTGC
TGGCTCGCATTGCACCGGGCATCGTGTGGGTAGCGGCTTTGTTGGCCTCGTTACTCTCGTTGGAGCGCTTATTCCGTGAT
GATTTTTACGATGGCTCCCTTGAACAGTTGCTGTTATTGCCTACACCACTCCCCCTCACCGTCTTAGGCAAAGTATGTGC
TCACTGGGTCGTCACTGGGCTGCCTTTATTGGTGTTATCACCGCTGGTTGCTTTATTGCTTTCTCTGGACGTCAATACCG
CTATCGCGATGGGGCTGACGCTCCTGCTTGGGACACCAACACTGAGTTTTATCGGTGCTATCGGCGTGGCGTTGACGGTG
GGGTTACGTAAAGGCGGGGTGCTGCTGAGTCTATTGGTTTTGCCGCTGTATATCCCGGTTTTAATCTTTGCGACGGCGGC
CATTGATGCCGCGTCAATGGCGATGCCAATCGACGGTTATCTGGCTATTTTAGGTGCGATGCTGGCAGGGAGTGTGACAC
TTGCGCCTTTTGCGACGGCAGCAGCGTTACGGGTGAGCATACAGTAA

Upstream 100 bases:

>100_bases
CGTTGTTGGCCCTGTTTGTACAACATGCGGCTAAGGGCGGAATGGTGCTGTTGACCACGCATCAGGATTTGGGCGCGGTT
AGCCACAATGTCCGTAAAAT

Downstream 100 bases:

>100_bases
TCACCCAATGGGCTGATGTTAAGTCTGCCTAATGTCCAATTTTTTACAGTGAGCAATGAAAAATGTGGAAATGGTTTCAT
CAATTTGCCAAACCTGAACG

Product: heme exporter protein B

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MFSQHAGEVMFISVLRRELKIAFRKGAEIVNPLWFFLIVITLFPLGIGPEPQLLARIAPGIVWVAALLASLLSLERLFRD
DFYDGSLEQLLLLPTPLPLTVLGKVCAHWVVTGLPLLVLSPLVALLLSLDVNTAIAMGLTLLLGTPTLSFIGAIGVALTV
GLRKGGVLLSLLVLPLYIPVLIFATAAIDAASMAMPIDGYLAILGAMLAGSVTLAPFATAAALRVSIQ

Sequences:

>Translated_228_residues
MFSQHAGEVMFISVLRRELKIAFRKGAEIVNPLWFFLIVITLFPLGIGPEPQLLARIAPGIVWVAALLASLLSLERLFRD
DFYDGSLEQLLLLPTPLPLTVLGKVCAHWVVTGLPLLVLSPLVALLLSLDVNTAIAMGLTLLLGTPTLSFIGAIGVALTV
GLRKGGVLLSLLVLPLYIPVLIFATAAIDAASMAMPIDGYLAILGAMLAGSVTLAPFATAAALRVSIQ
>Mature_228_residues
MFSQHAGEVMFISVLRRELKIAFRKGAEIVNPLWFFLIVITLFPLGIGPEPQLLARIAPGIVWVAALLASLLSLERLFRD
DFYDGSLEQLLLLPTPLPLTVLGKVCAHWVVTGLPLLVLSPLVALLLSLDVNTAIAMGLTLLLGTPTLSFIGAIGVALTV
GLRKGGVLLSLLVLPLYIPVLIFATAAIDAASMAMPIDGYLAILGAMLAGSVTLAPFATAAALRVSIQ

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=220, Percent_Identity=76.8181818181818, Blast_Score=271, Evalue=2e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 24115; Mature: 24115

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSQHAGEVMFISVLRRELKIAFRKGAEIVNPLWFFLIVITLFPLGIGPEPQLLARIAPG
CCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IVWVAALLASLLSLERLFRDDFYDGSLEQLLLLPTPLPLTVLGKVCAHWVVTGLPLLVLS
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
PLVALLLSLDVNTAIAMGLTLLLGTPTLSFIGAIGVALTVGLRKGGVLLSLLVLPLYIPV
HHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LIFATAAIDAASMAMPIDGYLAILGAMLAGSVTLAPFATAAALRVSIQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHEECC
>Mature Secondary Structure
MFSQHAGEVMFISVLRRELKIAFRKGAEIVNPLWFFLIVITLFPLGIGPEPQLLARIAPG
CCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IVWVAALLASLLSLERLFRDDFYDGSLEQLLLLPTPLPLTVLGKVCAHWVVTGLPLLVLS
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
PLVALLLSLDVNTAIAMGLTLLLGTPTLSFIGAIGVALTVGLRKGGVLLSLLVLPLYIPV
HHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LIFATAAIDAASMAMPIDGYLAILGAMLAGSVTLAPFATAAALRVSIQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]