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The map label for this gene is narP [H]

Identifier: 22125339

GI number: 22125339

Start: 1598894

End: 1599556

Strand: Reverse

Name: narP [H]

Synonym: y1441

Alternate gene names: 22125339

Gene position: 1599556-1598894 (Counterclockwise)

Preceding gene: 22125342

Following gene: 22125337

Centisome position: 34.77

GC content: 44.8

Gene sequence:

>663_bases
GTGCTTTTTGAGTTACAGGGAGAATTATTCATTATGACGAAAAGTCACACTATTCTGATCGTTGACGACCATCCGCTCAT
GCGCCGGGGGATTAAACAATTGCTGGGGCTAGATAGCCGCTTTGATGTGGTTGCTGAAGCGAACAATGGCAGCGACGCCA
TTACTGAAGCGGCCAAATTTCAACCAGATGTTATTTTGCTCGATCTGAATATGAAAGGCATGTCCGGGCTGGATACGTTA
AAAGCCCTGCGCCATAACGGCAGTGATGCACGGATCATTATTTTGACGGTCTCCGATGCGCGTAGTGATGTGTACGCGAT
GATTGATGCCGGTGCTGATGGTTATTTACTCAAAGATTGCGAGCCAGAAATATTACTGGAGAATATTCGCCAGGCAGCGC
GTGGGGAAAATGTCTTCAGCGACGAGGTGATCCAGTATTTATCATCTCGTCATGAACAAGTGAACCCTTTCTCTGAATTG
ACTGAACGTGAATTAGATGTCTTGCAAGAGGTGGCTCGTGGGATGTCCAATAAACAAGTTGCTTTCGAACTGCACATTTC
AGAAGAAACCGTGAAAGTACATATCCGTAATTTATTGCGTAAATTAAATGTGCGCTCACGGGTTGCCGCGACGATTATGT
ATTTGGAAAATAAAAAATACTGA

Upstream 100 bases:

>100_bases
CTTGGCGGTCAGGTGAGTAAAAACCGCGCGTAGCACTGCGACATCACGTAGAAAGGTATAAATCTTGCCATCAGTAACGG
CATATTAAGTACGTTACTGT

Downstream 100 bases:

>100_bases
CATCCGTTGTCACTATTTAATGGCCGCTAAAATAAAATCATGGTTTTCTTGTATCCATCTTTTATTCAGTGGCCCCCAAC
TCTCCAACTGGTAGTAACCC

Product: nitrate/nitrite response regulator protein NarP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MLFELQGELFIMTKSHTILIVDDHPLMRRGIKQLLGLDSRFDVVAEANNGSDAITEAAKFQPDVILLDLNMKGMSGLDTL
KALRHNGSDARIIILTVSDARSDVYAMIDAGADGYLLKDCEPEILLENIRQAARGENVFSDEVIQYLSSRHEQVNPFSEL
TERELDVLQEVARGMSNKQVAFELHISEETVKVHIRNLLRKLNVRSRVAATIMYLENKKY

Sequences:

>Translated_220_residues
MLFELQGELFIMTKSHTILIVDDHPLMRRGIKQLLGLDSRFDVVAEANNGSDAITEAAKFQPDVILLDLNMKGMSGLDTL
KALRHNGSDARIIILTVSDARSDVYAMIDAGADGYLLKDCEPEILLENIRQAARGENVFSDEVIQYLSSRHEQVNPFSEL
TERELDVLQEVARGMSNKQVAFELHISEETVKVHIRNLLRKLNVRSRVAATIMYLENKKY
>Mature_220_residues
MLFELQGELFIMTKSHTILIVDDHPLMRRGIKQLLGLDSRFDVVAEANNGSDAITEAAKFQPDVILLDLNMKGMSGLDTL
KALRHNGSDARIIILTVSDARSDVYAMIDAGADGYLLKDCEPEILLENIRQAARGENVFSDEVIQYLSSRHEQVNPFSEL
TERELDVLQEVARGMSNKQVAFELHISEETVKVHIRNLLRKLNVRSRVAATIMYLENKKY

Specific function: This protein activates the expression of the nitrate reductase (narGHJI) and formate dehydrogenase-N (fdnGHI) operons and represses the transcription of the fumarate reductase (frdABCD) operon in response to a nitrate/nitrite induction signal transmitted

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=204, Percent_Identity=67.6470588235294, Blast_Score=269, Evalue=9e-74,
Organism=Escherichia coli, GI1787473, Length=209, Percent_Identity=43.5406698564593, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1788222, Length=198, Percent_Identity=30.3030303030303, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1790102, Length=193, Percent_Identity=34.7150259067358, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1786747, Length=200, Percent_Identity=26.5, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1788712, Length=188, Percent_Identity=26.063829787234, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788546, Length=195, Percent_Identity=24.6153846153846, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24856; Mature: 24856

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFELQGELFIMTKSHTILIVDDHPLMRRGIKQLLGLDSRFDVVAEANNGSDAITEAAKF
CEEEECCCEEEEECCCEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHC
QPDVILLDLNMKGMSGLDTLKALRHNGSDARIIILTVSDARSDVYAMIDAGADGYLLKDC
CCCEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEECCCCCEEECCC
EPEILLENIRQAARGENVFSDEVIQYLSSRHEQVNPFSELTERELDVLQEVARGMSNKQV
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEE
AFELHISEETVKVHIRNLLRKLNVRSRVAATIMYLENKKY
EEEEEECHHHHHHHHHHHHHHHCHHHHHHHHHHEEECCCC
>Mature Secondary Structure
MLFELQGELFIMTKSHTILIVDDHPLMRRGIKQLLGLDSRFDVVAEANNGSDAITEAAKF
CEEEECCCEEEEECCCEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHC
QPDVILLDLNMKGMSGLDTLKALRHNGSDARIIILTVSDARSDVYAMIDAGADGYLLKDC
CCCEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEECCCCCEEECCC
EPEILLENIRQAARGENVFSDEVIQYLSSRHEQVNPFSELTERELDVLQEVARGMSNKQV
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEE
AFELHISEETVKVHIRNLLRKLNVRSRVAATIMYLENKKY
EEEEEECHHHHHHHHHHHHHHHCHHHHHHHHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501030; 9278503 [H]