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The map label for this gene is potC [H]

Identifier: 22125291

GI number: 22125291

Start: 1547936

End: 1548799

Strand: Direct

Name: potC [H]

Synonym: y1393

Alternate gene names: 22125291

Gene position: 1547936-1548799 (Clockwise)

Preceding gene: 22125290

Following gene: 22125297

Centisome position: 33.65

GC content: 54.05

Gene sequence:

>864_bases
GTGCCGGAGGAGACGATGCCGAAACCACAAAAGGCACTGAAACAAAAAGGGGCGTGGCTGCTTAGGGGGTGGAAATGGGT
CTTTAATTTTTACAGCGCCGCCATTTTATTATTCCTGATCGTACCGGTATTGGTCATTGTGCCGCTGTCGTTTAATGCGG
GTTCTTTTCTCAGTTACCCAATGGCGGGTTTTTCACTGCGTTGGTATCAGACCTTTTTCAACTCGGATGAGTGGCTGGGG
GCCTTGGGTAACAGCCTGCTGATTGCCCCGTTGGCGACCTTGCTGGCGACGGGGCTGGGGGTTTTGGCCGCCATTGGCTT
GGTGCGCGGGGAGTTTCGGGGCAAGGCGTTGGTGATGGCGATGTTGATTTCGCCAATGGTGGCCCCGGTGGTGATCATTG
CTGTTGGCATGTTTTTCTTCTTTGCCCGCTTATCACTGCTCAACAGCTACCTGGGATTAGTCTTGGCCCACGCCTTGCTT
GGGGTCCCATTTGTCGTGATCACCGTGACCGCTGTCTTGAAAAGTTATGATCAGAATCTGTCGCGGGCGGCCGCCAGCTT
GGGGGCATCACAGTGGCGGGTCTTTCGTAAGGTCACCTTACCGCTGATCGCCCCCGGTGTATTTTCAGGTGCCTTGTTTG
CTTTTGCGGTTTCGTTTGATGAAGTGGTCGTGACACTGTTTCTTGCCAGCCCGCGTCAGCGCACATTACCGATCAAAATG
TTTGCCGGTATCCGTGAAAATCTCGATCCGACTATTGCGGCGGCCGCTTCATTAATGGTTGGCGCTTCGCTGTTGTTACT
GATTGTGATGGAACTGCTCCGGCGGCGTAGTGAGCGTTTACGCCATCATCCAGTGTCCCCATAA

Upstream 100 bases:

>100_bases
TACGTGGTTTATATCCGAGTAACCCGTACCCAGGCTGAAACCGCGATTCATTAGTTCATCTATTGATGTGTTTATCCGTT
CATGAGCTTATCAACACATT

Downstream 100 bases:

>100_bases
TCTGCCGGGGAATAAGCCGAGGGGCATGGAATTAAATATAAACGCCGGATAGGGAGGTGAATGGAGGGCAGCATGTCTGA
GATGACCACGGCACAGGCGT

Product: ABC transporter permease

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MPEETMPKPQKALKQKGAWLLRGWKWVFNFYSAAILLFLIVPVLVIVPLSFNAGSFLSYPMAGFSLRWYQTFFNSDEWLG
ALGNSLLIAPLATLLATGLGVLAAIGLVRGEFRGKALVMAMLISPMVAPVVIIAVGMFFFFARLSLLNSYLGLVLAHALL
GVPFVVITVTAVLKSYDQNLSRAAASLGASQWRVFRKVTLPLIAPGVFSGALFAFAVSFDEVVVTLFLASPRQRTLPIKM
FAGIRENLDPTIAAAASLMVGASLLLLIVMELLRRRSERLRHHPVSP

Sequences:

>Translated_287_residues
MPEETMPKPQKALKQKGAWLLRGWKWVFNFYSAAILLFLIVPVLVIVPLSFNAGSFLSYPMAGFSLRWYQTFFNSDEWLG
ALGNSLLIAPLATLLATGLGVLAAIGLVRGEFRGKALVMAMLISPMVAPVVIIAVGMFFFFARLSLLNSYLGLVLAHALL
GVPFVVITVTAVLKSYDQNLSRAAASLGASQWRVFRKVTLPLIAPGVFSGALFAFAVSFDEVVVTLFLASPRQRTLPIKM
FAGIRENLDPTIAAAASLMVGASLLLLIVMELLRRRSERLRHHPVSP
>Mature_286_residues
PEETMPKPQKALKQKGAWLLRGWKWVFNFYSAAILLFLIVPVLVIVPLSFNAGSFLSYPMAGFSLRWYQTFFNSDEWLGA
LGNSLLIAPLATLLATGLGVLAAIGLVRGEFRGKALVMAMLISPMVAPVVIIAVGMFFFFARLSLLNSYLGLVLAHALLG
VPFVVITVTAVLKSYDQNLSRAAASLGASQWRVFRKVTLPLIAPGVFSGALFAFAVSFDEVVVTLFLASPRQRTLPIKMF
AGIRENLDPTIAAAASLMVGASLLLLIVMELLRRRSERLRHHPVSP

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=230, Percent_Identity=33.9130434782609, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1787081, Length=256, Percent_Identity=33.984375, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787714, Length=226, Percent_Identity=33.1858407079646, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786980, Length=223, Percent_Identity=30.4932735426009, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788764, Length=234, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082099, Length=227, Percent_Identity=27.7533039647577, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790464, Length=242, Percent_Identity=27.6859504132231, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31333; Mature: 31202

Theoretical pI: Translated: 11.23; Mature: 11.23

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PEETMPKPQKALKQKGAWLLRGWKWVFNFYSAAILLFLIVPVLVIVPLSFNAGSFLSYP
CCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCC
MAGFSLRWYQTFFNSDEWLGALGNSLLIAPLATLLATGLGVLAAIGLVRGEFRGKALVMA
CCCCHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLISPMVAPVVIIAVGMFFFFARLSLLNSYLGLVLAHALLGVPFVVITVTAVLKSYDQNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRAAASLGASQWRVFRKVTLPLIAPGVFSGALFAFAVSFDEVVVTLFLASPRQRTLPIKM
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
FAGIRENLDPTIAAAASLMVGASLLLLIVMELLRRRSERLRHHPVSP
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]