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The map label for this gene is tadA [H]

Identifier: 22125207

GI number: 22125207

Start: 1449259

End: 1449861

Strand: Direct

Name: tadA [H]

Synonym: y1307

Alternate gene names: 22125207

Gene position: 1449259-1449861 (Clockwise)

Preceding gene: 161484838

Following gene: 22125209

Centisome position: 31.5

GC content: 53.4

Gene sequence:

>603_bases
GTGTATAATGCCCGCCGCAAAAGTGCCAGAGAGGTTAATGTGTCTGCTGATAATAGTTTGCCTGCTGATAATGGCTTGTC
TTCTGAATGTGATTCTCCTGCTGAATACAGCGATGAGTACTGGATGCGCCATGCCTTAACGCTGGCGCTGCGAGCGCAGG
AAGAGGGTGAAGTTCCGGTGGGGGCAGTGCTGGTCTTGGGGAATAAGGTGATTGGTGAAGGGTGGAACCGGCCAATTCGC
GATAATGACCCAACTGCTCATGCGGAAATTATGGCGCTACGCCAAGGTGGGCAGGCGGTACAGAATTATCGCCTGTTGGA
TGCCACCTTATATGTGACGCTGGAACCTTGCGTGATGTGCGCCGGAGCCATGGTACACAGCCGGATCCGCCGGTTGGTTT
ATGGCGCAAATGATGTAAAAACTGGCGCCGCGGGGTCGCTGGTAGATATTTTGCGCCACCCTGGGATGAACCACCAAATA
GAGGTCAGTGCTGGCATACTGGCGATTGCGTGTTCCCATCAATTGAGTGCGTTCTTTCGCCAACGCCGTGAGCAGCAGAA
AGCATTGAAACAAGCACAGCGGGCAGCAGAAGGTAAATTCTGA

Upstream 100 bases:

>100_bases
AAAACCGGCGAATTACAGCAATTGGAGTAGCGAGCCATTTTAGCCACTAGCCAAAGCAACCCCCTGTTTTGCGACAAACT
AACCGACTCGCCAGCAAGCT

Downstream 100 bases:

>100_bases
CGGTGGCCAGGTGATGCGCCGCCCAGCATGTTATGACGGGCGGCGGTTGGTGACTAAATCACGGTGTAATTAAGGTTGAA
CGACTGCCGACGAGTGACTG

Product: tRNA-specific adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MYNARRKSAREVNVSADNSLPADNGLSSECDSPAEYSDEYWMRHALTLALRAQEEGEVPVGAVLVLGNKVIGEGWNRPIR
DNDPTAHAEIMALRQGGQAVQNYRLLDATLYVTLEPCVMCAGAMVHSRIRRLVYGANDVKTGAAGSLVDILRHPGMNHQI
EVSAGILAIACSHQLSAFFRQRREQQKALKQAQRAAEGKF

Sequences:

>Translated_200_residues
MYNARRKSAREVNVSADNSLPADNGLSSECDSPAEYSDEYWMRHALTLALRAQEEGEVPVGAVLVLGNKVIGEGWNRPIR
DNDPTAHAEIMALRQGGQAVQNYRLLDATLYVTLEPCVMCAGAMVHSRIRRLVYGANDVKTGAAGSLVDILRHPGMNHQI
EVSAGILAIACSHQLSAFFRQRREQQKALKQAQRAAEGKF
>Mature_200_residues
MYNARRKSAREVNVSADNSLPADNGLSSECDSPAEYSDEYWMRHALTLALRAQEEGEVPVGAVLVLGNKVIGEGWNRPIR
DNDPTAHAEIMALRQGGQAVQNYRLLDATLYVTLEPCVMCAGAMVHSRIRRLVYGANDVKTGAAGSLVDILRHPGMNHQI
EVSAGILAIACSHQLSAFFRQRREQQKALKQAQRAAEGKF

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=180, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI145693172, Length=166, Percent_Identity=71.0843373493976, Blast_Score=250, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI17541138, Length=164, Percent_Identity=34.7560975609756, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=42.2680412371134, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=32.1917808219178, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 21957; Mature: 21957

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNARRKSAREVNVSADNSLPADNGLSSECDSPAEYSDEYWMRHALTLALRAQEEGEVPV
CCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCE
GAVLVLGNKVIGEGWNRPIRDNDPTAHAEIMALRQGGQAVQNYRLLDATLYVTLEPCVMC
EEEEEECCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHEEEEEEEEEEEEHHHHHH
AGAMVHSRIRRLVYGANDVKTGAAGSLVDILRHPGMNHQIEVSAGILAIACSHQLSAFFR
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCEEEHHHHHHHHHHHH
QRREQQKALKQAQRAAEGKF
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYNARRKSAREVNVSADNSLPADNGLSSECDSPAEYSDEYWMRHALTLALRAQEEGEVPV
CCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCE
GAVLVLGNKVIGEGWNRPIRDNDPTAHAEIMALRQGGQAVQNYRLLDATLYVTLEPCVMC
EEEEEECCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHEEEEEEEEEEEEHHHHHH
AGAMVHSRIRRLVYGANDVKTGAAGSLVDILRHPGMNHQIEVSAGILAIACSHQLSAFFR
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCEEEHHHHHHHHHHHH
QRREQQKALKQAQRAAEGKF
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]