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The map label for this gene is yfiC [C]

Identifier: 22125188

GI number: 22125188

Start: 1431436

End: 1432194

Strand: Direct

Name: yfiC [C]

Synonym: y1288

Alternate gene names: 22125188

Gene position: 1431436-1432194 (Clockwise)

Preceding gene: 22125186

Following gene: 22125190

Centisome position: 31.11

GC content: 49.28

Gene sequence:

>759_bases
TTGGTGACTAATGTGGGCGAACAATTAAAAAAACAACCGGTATTACGTGGTGGCGGTTTCACCTTTAAACAATTCTTTGT
GGCACATGATCGCTGTGCAATGAAAGTGGGCACTGACGGCGTTCTGCTGGGGGCTTGGGTGCCGGTGTTACACGCCCGTA
GAGTTTTGGATATTGGCTGTGGCAGTGGGCTTATCGCCTTAATGATTGCCCAACGTTCATTGCCACAGGTGCAGATTGAC
GGGGTTGAACTGGAACCCGCCGCTGCGCAACAGGCGAGCAGTAATGTTGAGTTATCTCCTTGGGCTGAACGCATTCATAT
CCATCAGCAAGATATTCATCAGTTTGCTGAGAATCATCCTCATCAGTATGACCTGATTGTCAGTAACCCGCCTTACTTTG
CTCCGGCCATTGCTTGTCGAGATGAAGCCCGTGATACCGCGCGCTATACCGGGTCACTCACGCATGATGCTCTACTGAAC
TGTGCGGAGAAGCTTATCACAGAGGACGGGATGTTTTGTGTGGTTTTACCCCATGAGTTAGGAATTGAATTTGCCCGCCT
TGCTGGGCAACAGGGCTGGTTTGTCCGGTGCCAGGTTGATATCAGGGATCGCCCCGGTAAACCGTTACATCGAATGCTAC
TGACACTTTCAAGACAAGCGGGTGAGACGGTGTATCAACATTTAGCTCTGCGTCAGTCTGAAGGTATTTACTCACCTGAG
TTTTGCCAGCTCATCAGTGATTTCTATCTAAACTATTAA

Upstream 100 bases:

>100_bases
ATACTTCAAGCTGCATGTGCGTTGCTACGATCAATCACCCGAACCGATTTGTCTCTCGCTGGCTGCCTTACTGCAATTCG
AATTATTTAGAGTATAAATT

Downstream 100 bases:

>100_bases
TTTTAAATAAAGTAATTAATTTTAAATAAAATAATTAGCGTGAAATAAGAATCGGGCGTCGTAGAGACGCCCTGAGGTTA
TTGACAAAGTGCCCGCGACG

Product: hypothetical protein

Products: NA

Alternate protein names: tRNA m6A37 methyltransferase [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MVTNVGEQLKKQPVLRGGGFTFKQFFVAHDRCAMKVGTDGVLLGAWVPVLHARRVLDIGCGSGLIALMIAQRSLPQVQID
GVELEPAAAQQASSNVELSPWAERIHIHQQDIHQFAENHPHQYDLIVSNPPYFAPAIACRDEARDTARYTGSLTHDALLN
CAEKLITEDGMFCVVLPHELGIEFARLAGQQGWFVRCQVDIRDRPGKPLHRMLLTLSRQAGETVYQHLALRQSEGIYSPE
FCQLISDFYLNY

Sequences:

>Translated_252_residues
MVTNVGEQLKKQPVLRGGGFTFKQFFVAHDRCAMKVGTDGVLLGAWVPVLHARRVLDIGCGSGLIALMIAQRSLPQVQID
GVELEPAAAQQASSNVELSPWAERIHIHQQDIHQFAENHPHQYDLIVSNPPYFAPAIACRDEARDTARYTGSLTHDALLN
CAEKLITEDGMFCVVLPHELGIEFARLAGQQGWFVRCQVDIRDRPGKPLHRMLLTLSRQAGETVYQHLALRQSEGIYSPE
FCQLISDFYLNY
>Mature_252_residues
MVTNVGEQLKKQPVLRGGGFTFKQFFVAHDRCAMKVGTDGVLLGAWVPVLHARRVLDIGCGSGLIALMIAQRSLPQVQID
GVELEPAAAQQASSNVELSPWAERIHIHQQDIHQFAENHPHQYDLIVSNPPYFAPAIACRDEARDTARYTGSLTHDALLN
CAEKLITEDGMFCVVLPHELGIEFARLAGQQGWFVRCQVDIRDRPGKPLHRMLLTLSRQAGETVYQHLALRQSEGIYSPE
FCQLISDFYLNY

Specific function: Specifically methylates the adenine in position 37 of tRNA(Val) [H]

COG id: COG4123

COG function: function code R; Predicted O-methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI87082131, Length=241, Percent_Identity=51.8672199170125, Blast_Score=258, Evalue=2e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR007848
- InterPro:   IPR022882 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: =2.1.1.55 [H]

Molecular weight: Translated: 28189; Mature: 28189

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTNVGEQLKKQPVLRGGGFTFKQFFVAHDRCAMKVGTDGVLLGAWVPVLHARRVLDIGC
CCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEEECCCCEEHHHHHHHHHHHHHHCCCC
GSGLIALMIAQRSLPQVQIDGVELEPAAAQQASSNVELSPWAERIHIHQQDIHQFAENHP
CCHHHHHHHHHCCCCCEEECCEEECCHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHCCC
HQYDLIVSNPPYFAPAIACRDEARDTARYTGSLTHDALLNCAEKLITEDGMFCVVLPHEL
CEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEECHHH
GIEFARLAGQQGWFVRCQVDIRDRPGKPLHRMLLTLSRQAGETVYQHLALRQSEGIYSPE
CHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
FCQLISDFYLNY
HHHHHHHHHCCC
>Mature Secondary Structure
MVTNVGEQLKKQPVLRGGGFTFKQFFVAHDRCAMKVGTDGVLLGAWVPVLHARRVLDIGC
CCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEEECCCCEEHHHHHHHHHHHHHHCCCC
GSGLIALMIAQRSLPQVQIDGVELEPAAAQQASSNVELSPWAERIHIHQQDIHQFAENHP
CCHHHHHHHHHCCCCCEEECCEEECCHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHCCC
HQYDLIVSNPPYFAPAIACRDEARDTARYTGSLTHDALLNCAEKLITEDGMFCVVLPHEL
CEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEECHHH
GIEFARLAGQQGWFVRCQVDIRDRPGKPLHRMLLTLSRQAGETVYQHLALRQSEGIYSPE
CHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
FCQLISDFYLNY
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA