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The map label for this gene is hoxN [H]

Identifier: 22125145

GI number: 22125145

Start: 1393688

End: 1394770

Strand: Direct

Name: hoxN [H]

Synonym: y1245

Alternate gene names: 22125145

Gene position: 1393688-1394770 (Clockwise)

Preceding gene: 22125144

Following gene: 22125147

Centisome position: 30.29

GC content: 41.09

Gene sequence:

>1083_bases
TTGAAAATAATCTGGAGTGCGAATATGACGACAATAATCGCCAGCAGCAGCGCCTTTGGTAATCAGCAAACAAAGCGCAG
AGCCATCTACCTGCTAATCGGCCTGTTGGTGGTGAATGGGTTAGCTTGGGTCTGGGCTTTTGCTGAATTTAATGATAATG
CCGTGCTGATGGGAATGGCTTTCCTGGCCTACAGTTTTGGTTTGCGCCATGCGGTTGATGCGGATCATATTGCGGCTATT
GATAACGTCACGCGTAAACTCATGCAACAAGGTAAAACACCGATTGCTGTTGGGACTTTTTTCTCACTCGGCCATTCAAC
TATTGTGATCTTAGCTTCACTGGCAATTGCTGCGACCGCCATGGCATTTAAGAATAATATGGCGTGGTTTCACGAAACCG
GTGGTTTAATCGGGACGTTGGTGTCATCCGTTTTTTTATTGTTATTTGCTTTTCTCAATTTAACGATCCTGATTTCAGTG
TATAAAAAATTCAAACAAGTTAAAGCTGGGTATATTTATAAAGATGAAGAGCTTGACCTTCTGGTCGTGAATAACGGTGG
TCTGTTATCCAGAATGTTTAAACGTGTATTTAATATGGTCAATAAAAGCTGGCATATGTATCCAGTTGGTTTTTTGTTTG
GCTTAGGTTTTGATACCGCAACTGAAATTGGTGTTTTGGGGATATCAGCGGCCAGCGCCACTCACGGTATGAATTTGTGG
TCGATAATGGTGTTTCCGATTTTATTTGCGGCCGGAATGGCATTGATCGATTCACTGGATAATTTTGTGATGATTGGTGC
TTATGGCTGGGCATTTTCTAAACCTGTTCGTAAACTTTATTACAATATCACTATCACCGCTGCGTCGGTGATTATTGCTT
TCTTTATCGGTGGCATTGAAGCCTTGGGTTTGATTGCCGATAAGTTAAATTTAACTGGTGGTATCTGGACGCCAATTAAT
AATATCAGCGAGAACTTAGGTCAGATCGGTTACTGGATTATAGGGATGTTTATATGTTGCTGGTTAGTTTCTATTATTAA
TTACTATGTCCGTGGTTATGACAAGCTAAATATAAGCCGATAA

Upstream 100 bases:

>100_bases
TTCTGAACATGTTACCGGTCATATTTTATCGATCATATAGACCTCAAATTATTGGCGTTATCGTGTTGTCAGCGATAACG
CCAGGTCAGAACGGGTAGGG

Downstream 100 bases:

>100_bases
GTCATATTTATTGCGAGTGAATTATTAGACCCGCTGACACAATAAGTTGTATGTGCGTTGGTTAGGGAAGGCTAACAAAT
AGAGACACTCATTAACCGAT

Product: nickel transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MKIIWSANMTTIIASSSAFGNQQTKRRAIYLLIGLLVVNGLAWVWAFAEFNDNAVLMGMAFLAYSFGLRHAVDADHIAAI
DNVTRKLMQQGKTPIAVGTFFSLGHSTIVILASLAIAATAMAFKNNMAWFHETGGLIGTLVSSVFLLLFAFLNLTILISV
YKKFKQVKAGYIYKDEELDLLVVNNGGLLSRMFKRVFNMVNKSWHMYPVGFLFGLGFDTATEIGVLGISAASATHGMNLW
SIMVFPILFAAGMALIDSLDNFVMIGAYGWAFSKPVRKLYYNITITAASVIIAFFIGGIEALGLIADKLNLTGGIWTPIN
NISENLGQIGYWIIGMFICCWLVSIINYYVRGYDKLNISR

Sequences:

>Translated_360_residues
MKIIWSANMTTIIASSSAFGNQQTKRRAIYLLIGLLVVNGLAWVWAFAEFNDNAVLMGMAFLAYSFGLRHAVDADHIAAI
DNVTRKLMQQGKTPIAVGTFFSLGHSTIVILASLAIAATAMAFKNNMAWFHETGGLIGTLVSSVFLLLFAFLNLTILISV
YKKFKQVKAGYIYKDEELDLLVVNNGGLLSRMFKRVFNMVNKSWHMYPVGFLFGLGFDTATEIGVLGISAASATHGMNLW
SIMVFPILFAAGMALIDSLDNFVMIGAYGWAFSKPVRKLYYNITITAASVIIAFFIGGIEALGLIADKLNLTGGIWTPIN
NISENLGQIGYWIIGMFICCWLVSIINYYVRGYDKLNISR
>Mature_360_residues
MKIIWSANMTTIIASSSAFGNQQTKRRAIYLLIGLLVVNGLAWVWAFAEFNDNAVLMGMAFLAYSFGLRHAVDADHIAAI
DNVTRKLMQQGKTPIAVGTFFSLGHSTIVILASLAIAATAMAFKNNMAWFHETGGLIGTLVSSVFLLLFAFLNLTILISV
YKKFKQVKAGYIYKDEELDLLVVNNGGLLSRMFKRVFNMVNKSWHMYPVGFLFGLGFDTATEIGVLGISAASATHGMNLW
SIMVFPILFAAGMALIDSLDNFVMIGAYGWAFSKPVRKLYYNITITAASVIIAFFIGGIEALGLIADKLNLTGGIWTPIN
NISENLGQIGYWIIGMFICCWLVSIINYYVRGYDKLNISR

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 39650; Mature: 39650

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIWSANMTTIIASSSAFGNQQTKRRAIYLLIGLLVVNGLAWVWAFAEFNDNAVLMGMA
CEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
FLAYSFGLRHAVDADHIAAIDNVTRKLMQQGKTPIAVGTFFSLGHSTIVILASLAIAATA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHCHHHHHHHHHHHHHHHH
MAFKNNMAWFHETGGLIGTLVSSVFLLLFAFLNLTILISVYKKFKQVKAGYIYKDEELDL
HHHHCCCCEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEE
LVVNNGGLLSRMFKRVFNMVNKSWHMYPVGFLFGLGFDTATEIGVLGISAASATHGMNLW
EEECCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHCCCCCHHHHHEEEEEHHHHHCCCHHH
SIMVFPILFAAGMALIDSLDNFVMIGAYGWAFSKPVRKLYYNITITAASVIIAFFIGGIE
HHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGLIADKLNLTGGIWTPINNISENLGQIGYWIIGMFICCWLVSIINYYVRGYDKLNISR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKIIWSANMTTIIASSSAFGNQQTKRRAIYLLIGLLVVNGLAWVWAFAEFNDNAVLMGMA
CEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
FLAYSFGLRHAVDADHIAAIDNVTRKLMQQGKTPIAVGTFFSLGHSTIVILASLAIAATA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHCHHHHHHHHHHHHHHHH
MAFKNNMAWFHETGGLIGTLVSSVFLLLFAFLNLTILISVYKKFKQVKAGYIYKDEELDL
HHHHCCCCEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEE
LVVNNGGLLSRMFKRVFNMVNKSWHMYPVGFLFGLGFDTATEIGVLGISAASATHGMNLW
EEECCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHCCCCCHHHHHEEEEEHHHHHCCCHHH
SIMVFPILFAAGMALIDSLDNFVMIGAYGWAFSKPVRKLYYNITITAASVIIAFFIGGIE
HHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGLIADKLNLTGGIWTPINNISENLGQIGYWIIGMFICCWLVSIINYYVRGYDKLNISR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]