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The map label for this gene is gltJ [H]

Identifier: 22125091

GI number: 22125091

Start: 1331903

End: 1332694

Strand: Reverse

Name: gltJ [H]

Synonym: y1188

Alternate gene names: 22125091

Gene position: 1332694-1331903 (Counterclockwise)

Preceding gene: 22125092

Following gene: 22125090

Centisome position: 28.97

GC content: 46.97

Gene sequence:

>792_bases
TTGAATCATCAGTCATCAGGGTGGCTTATCCATCCTTTAAGGGAGTTTGTTATGGCAATAGACTGGAACTGGGGCATTTT
TTTACAGCCAGCCCCTTTCGGCAATACCACCTATCTCGGTTGGATTTGGTCCGGCTTTCAGGTCACGGTCGCATTATCAT
TATGTGCTTGGGTGATCGCCTTCTTCGTCGGTTCACTATTTGGTATTTTAAGAACGGTGCCCAACCGAATCCTTTCAGGA
ATAGGGGCTTGTTACGTTGAATTGTTTCGTAACGTACCACTGATCGTGCAATTTTTTACCTGGTATCTGGTGGTTCCCGA
ACTATTGCCAGTGAACCTTGGCACATGGTTTAAAAGTGAACTGGCACCCAATATACAGTTCTTCCTCTCATCTATGATTT
GCCTTGGATTATTCACTGCGGCGCGGGTTTGTGAACAGGTTCGCGCAGGAATTCAATCACTGCCTCGTGGTCAAAAAGCA
GCGGGCCTGGCAATGGGGCTCACCCTCACACAGACTTACCGCTATGTTTTACTGCCCAATGCATATCGGGTGATTATTCC
CCCGATGACCTCAGAAATGCTCAATCTGGTAAAAAACTCCGCAATTGCCTCAACCATCGGGCTAGTCGAAATGGCGGCAC
AAGCGGGTAAATTGCTGGATTATTCAGCGCATGCCTATGAATCCTTCACCGCCATCACCCTAGGTTATGTACTGATCAAT
GCCGTGATCATGCTGTTAATGCGCTTAGTTGAAAAGAAAGTGCAATTACCCGGCAATCTGGGGAGTAAATAA

Upstream 100 bases:

>100_bases
TACCTGCCCTACCGATTGATGATGGCCTATTGGTAGACAGGATGCGGGGTGGTCGTTCCCCACCCCGCATTTTTTTGTCA
ACCCTCGGGAGCCGAAGGTA

Downstream 100 bases:

>100_bases
TGTACGAATTTGATTGGAGTTCCATCGCCCCCAGCCTGCCCTATCTGCTGCAAGGCTTGATTGTAACTGTCAAAATAACC
CTCATCGCCATTGTGTTCGG

Product: glutamate/aspartate ABC transport system inner membrane permease

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MNHQSSGWLIHPLREFVMAIDWNWGIFLQPAPFGNTTYLGWIWSGFQVTVALSLCAWVIAFFVGSLFGILRTVPNRILSG
IGACYVELFRNVPLIVQFFTWYLVVPELLPVNLGTWFKSELAPNIQFFLSSMICLGLFTAARVCEQVRAGIQSLPRGQKA
AGLAMGLTLTQTYRYVLLPNAYRVIIPPMTSEMLNLVKNSAIASTIGLVEMAAQAGKLLDYSAHAYESFTAITLGYVLIN
AVIMLLMRLVEKKVQLPGNLGSK

Sequences:

>Translated_263_residues
MNHQSSGWLIHPLREFVMAIDWNWGIFLQPAPFGNTTYLGWIWSGFQVTVALSLCAWVIAFFVGSLFGILRTVPNRILSG
IGACYVELFRNVPLIVQFFTWYLVVPELLPVNLGTWFKSELAPNIQFFLSSMICLGLFTAARVCEQVRAGIQSLPRGQKA
AGLAMGLTLTQTYRYVLLPNAYRVIIPPMTSEMLNLVKNSAIASTIGLVEMAAQAGKLLDYSAHAYESFTAITLGYVLIN
AVIMLLMRLVEKKVQLPGNLGSK
>Mature_263_residues
MNHQSSGWLIHPLREFVMAIDWNWGIFLQPAPFGNTTYLGWIWSGFQVTVALSLCAWVIAFFVGSLFGILRTVPNRILSG
IGACYVELFRNVPLIVQFFTWYLVVPELLPVNLGTWFKSELAPNIQFFLSSMICLGLFTAARVCEQVRAGIQSLPRGQKA
AGLAMGLTLTQTYRYVLLPNAYRVIIPPMTSEMLNLVKNSAIASTIGLVEMAAQAGKLLDYSAHAYESFTAITLGYVLIN
AVIMLLMRLVEKKVQLPGNLGSK

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786874, Length=246, Percent_Identity=85.3658536585366, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI1788226, Length=216, Percent_Identity=30.0925925925926, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI48994930, Length=125, Percent_Identity=39.2, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1786873, Length=215, Percent_Identity=26.046511627907, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787030, Length=213, Percent_Identity=24.8826291079812, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788645, Length=221, Percent_Identity=28.0542986425339, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787086, Length=221, Percent_Identity=25.7918552036199, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI87082239, Length=169, Percent_Identity=27.2189349112426, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29184; Mature: 29184

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHQSSGWLIHPLREFVMAIDWNWGIFLQPAPFGNTTYLGWIWSGFQVTVALSLCAWVIA
CCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
FFVGSLFGILRTVPNRILSGIGACYVELFRNVPLIVQFFTWYLVVPELLPVNLGTWFKSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LAPNIQFFLSSMICLGLFTAARVCEQVRAGIQSLPRGQKAAGLAMGLTLTQTYRYVLLPN
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEECCC
AYRVIIPPMTSEMLNLVKNSAIASTIGLVEMAAQAGKLLDYSAHAYESFTAITLGYVLIN
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHH
AVIMLLMRLVEKKVQLPGNLGSK
HHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNHQSSGWLIHPLREFVMAIDWNWGIFLQPAPFGNTTYLGWIWSGFQVTVALSLCAWVIA
CCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
FFVGSLFGILRTVPNRILSGIGACYVELFRNVPLIVQFFTWYLVVPELLPVNLGTWFKSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LAPNIQFFLSSMICLGLFTAARVCEQVRAGIQSLPRGQKAAGLAMGLTLTQTYRYVLLPN
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEECCC
AYRVIIPPMTSEMLNLVKNSAIASTIGLVEMAAQAGKLLDYSAHAYESFTAITLGYVLIN
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHH
AVIMLLMRLVEKKVQLPGNLGSK
HHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]