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The map label for this gene is yrbE [H]

Identifier: 22125055

GI number: 22125055

Start: 1301405

End: 1302541

Strand: Direct

Name: yrbE [H]

Synonym: y1152

Alternate gene names: 22125055

Gene position: 1301405-1302541 (Clockwise)

Preceding gene: 22125054

Following gene: 22125056

Centisome position: 28.29

GC content: 56.38

Gene sequence:

>1137_bases
ATGATGAAAGAAGTGCGTATTGGATTGATTGGTACCGGGTATATCGGTAAGGCGCACGCCATTGCCTACGCACAGGCACC
GACGGTGTTTGAATTGCGCGGCAAACTGGTGCGCGAAATGGTGGCCGAAGTCTCACCAGCGCTGGCGGCACAGCGTGCGC
AGGCTTTCGGTTTCAACCGGTTTACCTGCGACTGGCGGGAGCTGGTCGCGGATCCGGCTATTGATGTGGTTGATATTTGC
TCACCTAATTATCTACATAAAGAGATGGCGCTGGCGGCCATCCACCACGGCAAACATGTCTATGCGGAGAAACCGCTGGC
GCTGAATGCCCGTGACGCCAGCGAGATGGCGGCGGCCGCAACGCGCGCTGGGGTGAAAACGTTGGTAGGGTTCAATTACA
TCAAAAACCCCAGTGCGAAGCTGGCTAAAGAGATCATTGAACGTGGTGAAATCGGTGAGGTGATCCACTTTTATGGCACC
CATAACGAAGACTATATGGCCGATCCCAATACCCCTATTCACTGGCACTGTTTACACGCGACGGCAGGGCTGGGAGCACT
TGGCGATCTGGCGGCCCACATCGTCAGCATGGCGCAATATCTGGTGGGGGAAATAACGCAGGTATGCGGTGATCTGAAAA
CCGTCGTGGTGACACGCCCGGCGAGCGTTGGCTCCAGCGCCAGAGTGGCGGTTGAAAACGAAGATCAGGCCCATGCCATG
GTGCGTTTTGTGAATGGCGCTCAGGGAGTGATTGAAGCCTCGCGGGTGGCTTGCGGGCGCAAAATGGGCCTCTCTTACAT
GATTACCGGTACTCAAGGGGCGATCAGTTTTACCCAAGAACGTATGGCGGAACTCAAACTCTACCTGCACAACGACCCGG
TCAACCGACAAGGCTTCCGTACCCTGCTCGTCGGCCCGGCGCACCCAGAGTATGCCGCGTTCTGTATGGCTGCGGGCCAC
GGTATTGGTTTTAACGATCAAAAAACCGTGGAAGTGCGTGACTTGATCGACGGCATCGCGATGGACACGCCGCTGTGGCC
CGATTTCGCCGAGGGCTGGAAAGTCTCACGCATTCTCGATGCGATTGCTCTGTCTCATCAGGATAGCCGCTGGGTGAATG
TGACCGACATTGTCTGA

Upstream 100 bases:

>100_bases
AGCAAATTATCACCGGCCTGATCATCGTATTGGCGGTGGCCTTTGATACCTACGCCAAGAACCGTCGCGGCGCGCTGTAA
TACGTTCATGTCAGGAGTGA

Downstream 100 bases:

>100_bases
GGATGAGGTATGACAGGGTCTGAGGGGGGGTATGAGTGTGGAAAAGCAATTTAGCGTTAGCGCGGAAAAGACATGTAATA
CGGAAAATAAATGTAATACG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MMKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNRFTCDWRELVADPAIDVVDIC
SPNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAATRAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGT
HNEDYMADPNTPIHWHCLHATAGLGALGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAM
VRFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFRTLLVGPAHPEYAAFCMAAGH
GIGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILDAIALSHQDSRWVNVTDIV

Sequences:

>Translated_378_residues
MMKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNRFTCDWRELVADPAIDVVDIC
SPNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAATRAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGT
HNEDYMADPNTPIHWHCLHATAGLGALGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAM
VRFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFRTLLVGPAHPEYAAFCMAAGH
GIGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILDAIALSHQDSRWVNVTDIV
>Mature_378_residues
MMKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNRFTCDWRELVADPAIDVVDIC
SPNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAATRAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGT
HNEDYMADPNTPIHWHCLHATAGLGALGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAM
VRFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFRTLLVGPAHPEYAAFCMAAGH
GIGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILDAIALSHQDSRWVNVTDIV

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=153, Percent_Identity=32.0261437908497, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87081947, Length=275, Percent_Identity=24.7272727272727, Blast_Score=65, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323975, Length=212, Percent_Identity=26.8867924528302, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581117, Length=285, Percent_Identity=25.2631578947368, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 41101; Mature: 41101

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNR
CCCCEEEEEEECCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FTCDWRELVADPAIDVVDICSPNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAA
CCCCHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEECCCCEECCCCHHHHHHHH
TRAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGTHNEDYMADPNTPIHWHCLHA
HHHHHHHHHCCHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEH
TAGLGALGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAM
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCCHHHHH
VRFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFR
HHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHEEEEEECCCCCCCCCE
TLLVGPAHPEYAAFCMAAGHGIGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILD
EEEECCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCHHHHHHH
AIALSHQDSRWVNVTDIV
HHHHCCCCCCEEEEECCC
>Mature Secondary Structure
MMKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNR
CCCCEEEEEEECCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FTCDWRELVADPAIDVVDICSPNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAA
CCCCHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEECCCCEECCCCHHHHHHHH
TRAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGTHNEDYMADPNTPIHWHCLHA
HHHHHHHHHCCHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEH
TAGLGALGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAM
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCCHHHHH
VRFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFR
HHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHEEEEEECCCCCCCCCE
TLLVGPAHPEYAAFCMAAGHGIGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILD
EEEECCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCHHHHHHH
AIALSHQDSRWVNVTDIV
HHHHCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]