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The map label for this gene is thiJ [H]

Identifier: 22124920

GI number: 22124920

Start: 1141144

End: 1141740

Strand: Reverse

Name: thiJ [H]

Synonym: y1013

Alternate gene names: 22124920

Gene position: 1141740-1141144 (Counterclockwise)

Preceding gene: 22124921

Following gene: 161484851

Centisome position: 24.82

GC content: 50.92

Gene sequence:

>597_bases
GTGATTATGAGCGTATCGGCGCTGGTTTGCCTGGCTCCTGGTAGCGAGGAAACCGAGGCAGTCACAACTATTGATATTCT
GGTGCGCGCAGGCATCAATGTCACAACCGCCAGTGTCGCGGGTGATGGCGCACTGGAGATTATCTGTTCGCGCGGAGTGA
GGCTGTTGGCCGATACCCGTTTAGTGGATGTCGCCGATCAAAAATTTGATGTGATAGTGCTCCCCGGTGGGATTAAAGGC
GCGGAGTGCTTTCGCGATAGTCCGTTGCTGGTTGCAACAGTCCGACAAACCCATAATGAGGGCCGTTTGGTTGCCGCAAT
TTGTGCGGCTCCCGCACTGGTGCTCGAGCATCACCAGTTATTTCCCGTAGGGAATATGACCGGGTTCCCCTCACTAAAAG
ATAAAATAGCCCCAAATAAATGGATGGATCAACGCGTCGTCTACGATAGACGGGTTAATTTAGTCACCAGCCAAGGGCCA
GGAACATCCATCGATTTCGCTCTAAAAATTGTGTTTTTATTACTTGGACGGGAAAAGGCGGAAGAAATTGCCTGGCAGCT
AGTGTTGCCGCCAGGAATTTATAATTATCGGGAATGA

Upstream 100 bases:

>100_bases
ATCGACTATATAACCGGTTATTTACTGCGGCGCGCCCGTAGTCATGGTATGGCATTACCAGAAAATGCTCGACTGTATGA
ATTAATCAAACGTAAGGAAA

Downstream 100 bases:

>100_bases
TGGCCGCCGTAACGGTTACTGCGCAAATCCTGAATGGCAACGCGCAGTGCCGTCAATTATCAAAAAACTAAGGGCGATAG
ACTTTCACGTTGGTATACCC

Product: DJ-1 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MIMSVSALVCLAPGSEETEAVTTIDILVRAGINVTTASVAGDGALEIICSRGVRLLADTRLVDVADQKFDVIVLPGGIKG
AECFRDSPLLVATVRQTHNEGRLVAAICAAPALVLEHHQLFPVGNMTGFPSLKDKIAPNKWMDQRVVYDRRVNLVTSQGP
GTSIDFALKIVFLLLGREKAEEIAWQLVLPPGIYNYRE

Sequences:

>Translated_198_residues
MIMSVSALVCLAPGSEETEAVTTIDILVRAGINVTTASVAGDGALEIICSRGVRLLADTRLVDVADQKFDVIVLPGGIKG
AECFRDSPLLVATVRQTHNEGRLVAAICAAPALVLEHHQLFPVGNMTGFPSLKDKIAPNKWMDQRVVYDRRVNLVTSQGP
GTSIDFALKIVFLLLGREKAEEIAWQLVLPPGIYNYRE
>Mature_198_residues
MIMSVSALVCLAPGSEETEAVTTIDILVRAGINVTTASVAGDGALEIICSRGVRLLADTRLVDVADQKFDVIVLPGGIKG
AECFRDSPLLVATVRQTHNEGRLVAAICAAPALVLEHHQLFPVGNMTGFPSLKDKIAPNKWMDQRVVYDRRVNLVTSQGP
GTSIDFALKIVFLLLGREKAEEIAWQLVLPPGIYNYRE

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=192, Percent_Identity=39.5833333333333, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI31543380, Length=192, Percent_Identity=39.5833333333333, Blast_Score=113, Evalue=1e-25,
Organism=Escherichia coli, GI87081736, Length=196, Percent_Identity=73.9795918367347, Blast_Score=296, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI17531319, Length=187, Percent_Identity=39.0374331550802, Blast_Score=120, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17558714, Length=192, Percent_Identity=36.4583333333333, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI28571932, Length=188, Percent_Identity=45.7446808510638, Blast_Score=150, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24653499, Length=187, Percent_Identity=39.572192513369, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 21422; Mature: 21422

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMSVSALVCLAPGSEETEAVTTIDILVRAGINVTTASVAGDGALEIICSRGVRLLADTR
CEEEEEEEEEECCCCCCCHHHHHEEHHHHCCCCEEEEEECCCCHHEEHHHCCCEEEECCE
LVDVADQKFDVIVLPGGIKGAECFRDSPLLVATVRQTHNEGRLVAAICAAPALVLEHHQL
EEEECCCCEEEEEECCCCCHHHHHCCCCEEEEEEECCCCCCCEEEEHHHCHHHHHHCCCE
FPVGNMTGFPSLKDKIAPNKWMDQRVVYDRRVNLVTSQGPGTSIDFALKIVFLLLGREKA
EECCCCCCCCCCHHHCCCCCHHHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHCCCHH
EEIAWQLVLPPGIYNYRE
HHEEEEEEECCCCCCCCC
>Mature Secondary Structure
MIMSVSALVCLAPGSEETEAVTTIDILVRAGINVTTASVAGDGALEIICSRGVRLLADTR
CEEEEEEEEEECCCCCCCHHHHHEEHHHHCCCCEEEEEECCCCHHEEHHHCCCEEEECCE
LVDVADQKFDVIVLPGGIKGAECFRDSPLLVATVRQTHNEGRLVAAICAAPALVLEHHQL
EEEECCCCEEEEEECCCCCHHHHHCCCCEEEEEEECCCCCCCEEEEHHHCHHHHHHCCCE
FPVGNMTGFPSLKDKIAPNKWMDQRVVYDRRVNLVTSQGPGTSIDFALKIVFLLLGREKA
EECCCCCCCCCCHHHCCCCCHHHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHCCCHH
EEIAWQLVLPPGIYNYRE
HHEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]