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The map label for this gene is nqrA [H]

Identifier: 22124858

GI number: 22124858

Start: 1072065

End: 1073426

Strand: Direct

Name: nqrA [H]

Synonym: y0951

Alternate gene names: 22124858

Gene position: 1072065-1073426 (Clockwise)

Preceding gene: 22124855

Following gene: 22124859

Centisome position: 23.3

GC content: 51.03

Gene sequence:

>1362_bases
ATGAAGTCGTTTAAACCTATGATTAAAATAAAGAAAGGGCTAGATCTTCCCATTGCTGGAGCCCCCGTTCAGACGATACA
AGATGGTCCAGCGATTCATCATGTGGCCCTGCTCGGTGAAGAGTATGTTGGTATGCGTCCTTCAATGTTGGTGCAAGAAG
GCGATCAGGTTAAAAAAGGTCAGGCGCTGTTTGAAGACAAAAAGAATCCGGGCGTGTTGTTTACCGCCCCTGCCAGCGGC
AAAATCAGTGCTATCAATCGTGGTGAGCGTCGAGTATTGCAATCGGTGGTGATTGAAGTTGAAGGTGATGAGCAAATCCC
TTTCGAGCATTATGCTGCTGAGGAGCTTAATCAACTGAGCGATGAGCAGGTTCAACACCATCTGTTGACGTCCGGTTTAT
GGACTGCGCTGCGGACTCGCCCATTCAGTAAAACACCGGTTCCAGGCAGCCGTCCGCGCGCTATCTTTATCAGTGCGATG
GATACCCAACCGTTGGCGGCAGATCCGCAGGTTATTATTGCCACTGAATCAGAGGCGTTTAACCATGGCTTGACCGTATT
GACGCGGCTGACGGACGGTAAAGTACACGTCTGCCACGCGGCAGGGCAGGCTGTGACTCGTCATACCAATACGCAAGTGA
CTTACAACGAATTCTCCGGGCCGCACCCTGCGGGTCTGGTGGGGACACATATTCATTTTCTTGAGCCAGTCAGCCAGACC
AAAATGGTTTGGCATGTGGGCTATCAGGATGTCATTGCTATCGGTAAATTGTTTACCCGTGGTGAGTTGTGTACTGACCG
CATCGTCGCTTTGGCGGGTCCACAGGTGAATCAACCCATTTTATTGCGTACTCGTTTAGGGGCCAGCTTATCTGAACTGA
CCGCCGGTAAACTAAAAGAGGGTGATAACCGCATTATTTCAGGTTCAGTCCTCAGCGGTACCGCGTTCTCTGCTACCCAT
GGGTATCTGGGGCGTTTTCATCAGCAAGTCTCCGTTATCCGCGAAGGGCGTGAAAAAGAGTTATTTGGTTGGGTGATGCC
GGGGCGCGATAAATACTCCATTACCCGCACGACGCTGGGCCACTTCTTCAAACGCAAATTGTTTGCTTTCTCGACTGATA
TGCACGGTGGTGAGCGTGCCATGGTGCCAATTGGCAACTATGAGCGGGTCATGCCACTGGATATCCTGGCGACCCATCTG
CTACGTGATTTATTGGCCGGTGATACCGACAGCGCACAAGCACTCGGTTGTTTGGAGTTGGACGAAGAAGATCTGGCTTT
GTGTACTTTTGTTTGTCCCGGTAAGTACGAATACGGTCCGGTACTGCGCGACATACTGACCCAGATTGAGCAGGAAGGAT
AA

Upstream 100 bases:

>100_bases
ACAATCCAGTATTGCACCGTCGCTTAATTGAACAGTGGAAATACCTCATCTTTACGTAGCTGTACGCTTCAGGGTTTATG
TGCAGCATTTGATATCACTA

Downstream 100 bases:

>100_bases
CTGATGGGCCTGAAAAATTTTCTTGAGAAAATCGAACACCACTTTGAAGCGGGTGGGAAATTAGAAAAGTACTATCCGCT
GTACGAAGCTGCCGCAACCA

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MKSFKPMIKIKKGLDLPIAGAPVQTIQDGPAIHHVALLGEEYVGMRPSMLVQEGDQVKKGQALFEDKKNPGVLFTAPASG
KISAINRGERRVLQSVVIEVEGDEQIPFEHYAAEELNQLSDEQVQHHLLTSGLWTALRTRPFSKTPVPGSRPRAIFISAM
DTQPLAADPQVIIATESEAFNHGLTVLTRLTDGKVHVCHAAGQAVTRHTNTQVTYNEFSGPHPAGLVGTHIHFLEPVSQT
KMVWHVGYQDVIAIGKLFTRGELCTDRIVALAGPQVNQPILLRTRLGASLSELTAGKLKEGDNRIISGSVLSGTAFSATH
GYLGRFHQQVSVIREGREKELFGWVMPGRDKYSITRTTLGHFFKRKLFAFSTDMHGGERAMVPIGNYERVMPLDILATHL
LRDLLAGDTDSAQALGCLELDEEDLALCTFVCPGKYEYGPVLRDILTQIEQEG

Sequences:

>Translated_453_residues
MKSFKPMIKIKKGLDLPIAGAPVQTIQDGPAIHHVALLGEEYVGMRPSMLVQEGDQVKKGQALFEDKKNPGVLFTAPASG
KISAINRGERRVLQSVVIEVEGDEQIPFEHYAAEELNQLSDEQVQHHLLTSGLWTALRTRPFSKTPVPGSRPRAIFISAM
DTQPLAADPQVIIATESEAFNHGLTVLTRLTDGKVHVCHAAGQAVTRHTNTQVTYNEFSGPHPAGLVGTHIHFLEPVSQT
KMVWHVGYQDVIAIGKLFTRGELCTDRIVALAGPQVNQPILLRTRLGASLSELTAGKLKEGDNRIISGSVLSGTAFSATH
GYLGRFHQQVSVIREGREKELFGWVMPGRDKYSITRTTLGHFFKRKLFAFSTDMHGGERAMVPIGNYERVMPLDILATHL
LRDLLAGDTDSAQALGCLELDEEDLALCTFVCPGKYEYGPVLRDILTQIEQEG
>Mature_453_residues
MKSFKPMIKIKKGLDLPIAGAPVQTIQDGPAIHHVALLGEEYVGMRPSMLVQEGDQVKKGQALFEDKKNPGVLFTAPASG
KISAINRGERRVLQSVVIEVEGDEQIPFEHYAAEELNQLSDEQVQHHLLTSGLWTALRTRPFSKTPVPGSRPRAIFISAM
DTQPLAADPQVIIATESEAFNHGLTVLTRLTDGKVHVCHAAGQAVTRHTNTQVTYNEFSGPHPAGLVGTHIHFLEPVSQT
KMVWHVGYQDVIAIGKLFTRGELCTDRIVALAGPQVNQPILLRTRLGASLSELTAGKLKEGDNRIISGSVLSGTAFSATH
GYLGRFHQQVSVIREGREKELFGWVMPGRDKYSITRTTLGHFFKRKLFAFSTDMHGGERAMVPIGNYERVMPLDILATHL
LRDLLAGDTDSAQALGCLELDEEDLALCTFVCPGKYEYGPVLRDILTQIEQEG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008703
- InterPro:   IPR022615 [H]

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB [H]

EC number: NA

Molecular weight: Translated: 49736; Mature: 49736

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFKPMIKIKKGLDLPIAGAPVQTIQDGPAIHHVALLGEEYVGMRPSMLVQEGDQVKKG
CCCCCCHHHHHCCCCCCCCCCCHHHHCCCCCHHHHEECCHHHCCCCCHHHHHCCCCHHCC
QALFEDKKNPGVLFTAPASGKISAINRGERRVLQSVVIEVEGDEQIPFEHYAAEELNQLS
CHHHHCCCCCCEEEECCCCCCEEECCCHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHH
DEQVQHHLLTSGLWTALRTRPFSKTPVPGSRPRAIFISAMDTQPLAADPQVIIATESEAF
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCHH
NHGLTVLTRLTDGKVHVCHAAGQAVTRHTNTQVTYNEFSGPHPAGLVGTHIHFLEPVSQT
HCCEEEEEEECCCCEEEEECCCCHHHCCCCCEEEECCCCCCCCCCHHHCHHHHHCCCCCC
KMVWHVGYQDVIAIGKLFTRGELCTDRIVALAGPQVNQPILLRTRLGASLSELTAGKLKE
EEEEECCHHHHHHHHHHHHCCCHHHHHEEEECCCCCCCCEEEEECCCCCHHHHHHHHCCC
GDNRIISGSVLSGTAFSATHGYLGRFHQQVSVIREGREKELFGWVMPGRDKYSITRTTLG
CCCEEEECCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEHHHHHH
HFFKRKLFAFSTDMHGGERAMVPIGNYERVMPLDILATHLLRDLLAGDTDSAQALGCLEL
HHHHHHHHHEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEEEC
DEEDLALCTFVCPGKYEYGPVLRDILTQIEQEG
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSFKPMIKIKKGLDLPIAGAPVQTIQDGPAIHHVALLGEEYVGMRPSMLVQEGDQVKKG
CCCCCCHHHHHCCCCCCCCCCCHHHHCCCCCHHHHEECCHHHCCCCCHHHHHCCCCHHCC
QALFEDKKNPGVLFTAPASGKISAINRGERRVLQSVVIEVEGDEQIPFEHYAAEELNQLS
CHHHHCCCCCCEEEECCCCCCEEECCCHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHH
DEQVQHHLLTSGLWTALRTRPFSKTPVPGSRPRAIFISAMDTQPLAADPQVIIATESEAF
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCHH
NHGLTVLTRLTDGKVHVCHAAGQAVTRHTNTQVTYNEFSGPHPAGLVGTHIHFLEPVSQT
HCCEEEEEEECCCCEEEEECCCCHHHCCCCCEEEECCCCCCCCCCHHHCHHHHHCCCCCC
KMVWHVGYQDVIAIGKLFTRGELCTDRIVALAGPQVNQPILLRTRLGASLSELTAGKLKE
EEEEECCHHHHHHHHHHHHCCCHHHHHEEEECCCCCCCCEEEEECCCCCHHHHHHHHCCC
GDNRIISGSVLSGTAFSATHGYLGRFHQQVSVIREGREKELFGWVMPGRDKYSITRTTLG
CCCEEEECCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEHHHHHH
HFFKRKLFAFSTDMHGGERAMVPIGNYERVMPLDILATHLLRDLLAGDTDSAQALGCLEL
HHHHHHHHHEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEEEC
DEEDLALCTFVCPGKYEYGPVLRDILTQIEQEG
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA