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The map label for this gene is lsrR [H]

Identifier: 22124754

GI number: 22124754

Start: 942813

End: 943811

Strand: Reverse

Name: lsrR [H]

Synonym: y0843

Alternate gene names: 22124754

Gene position: 943811-942813 (Counterclockwise)

Preceding gene: 22124755

Following gene: 22124748

Centisome position: 20.51

GC content: 50.25

Gene sequence:

>999_bases
GTGATAAGTGGCCGAGGGCAGCTCTCTATGGAAAAGCAGATGATCCCACAAGACAATGAGTTGTTAACTGAAATTGCTGT
TTCGTATTATCAGGATGAAATGACTCAGGAAGAAATCGCCCATAAATTTGGCATTTCAAGGATCAAAGTCGGTCGCTTGC
TGAAACGCGCGAAAACAGAGGGCATCGTTGAGATTAACGTTCGTTATCATCCGGTATTCAGTACCCGCCTTGAGCAACAG
TTAATCGAGCATTTTGGGTTGAAACGGGCGCTGATAGCCCTTGATTACCAAGATGAGGATGAACAACGCCGCCAGGTCGC
CGCGTTGGTTTCAGCCTACTTAGCCACAAACTTAAAAGACAACACGGTGTTGGCCGTTGGCCAGGGGCGTAATGTTGCGG
CTATCGCAGACCACGTCAGCGTCGTGCCAGAAAGGCACTGTAAGTTTATCTGTGGCATCGGTGGAACACACCGCCCAGGT
GATGCGATTAATGCCGATCACATCAGTCGCCGCTTAGCCAAAAAATTTGGCGGAACGAGTGAAACCCTGTACGCACCCGC
GTATGTGGAAAACCGGGCGCTAAAAGAAGCCTTTATGCAAAACGGTACCATTAAAGAGACTCTGGACCGCGCCCGTAAGG
CTGATATGGCTCTGGTTGGCATCGGTGATATGAACGAAAACAGCTATATGGTAGAGCTGGGCTGGTTCACTCCTCAGGAG
ATCGTCGACGCCAGTCTGCATCAAGGTGTGACAGGCGAAATTGCGGGATATGATTTTTTTGATGCGCAAGGCCAGCCCGC
GAATACGGTGATGAATGATCGGGTTATTGGTATCAGCACCCAAGAGCTTCGCCAGATCCCCTGCGTTATCGCTATCGCCG
CTGAAAACACCAAAGCATTAGCGCTGCTGGGTGCCTTGCGTACCGGTGCGATCGATATTCTTGCGACCAGTGCATCCAAT
GCCCGGACTATTTTGAAGATGATTCAACATCAGTCGTAA

Upstream 100 bases:

>100_bases
AGAAAAGGCAAATTTTTCTGTTCACCCTACTATACAAATGCTCTACTATTCATTCCTGTTTAAAACAATAACCCTTCACC
TTATGTGATACGTTCCGAGT

Downstream 100 bases:

>100_bases
TATTACAGACAGATAAAAGAGAGATAAAAAGACCAATAGCGATTGGGGCAGTCTCGTGACTGAGTGCCCACATCGCTTCT
TCACCTGAATACCACGGTCA

Product: transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MISGRGQLSMEKQMIPQDNELLTEIAVSYYQDEMTQEEIAHKFGISRIKVGRLLKRAKTEGIVEINVRYHPVFSTRLEQQ
LIEHFGLKRALIALDYQDEDEQRRQVAALVSAYLATNLKDNTVLAVGQGRNVAAIADHVSVVPERHCKFICGIGGTHRPG
DAINADHISRRLAKKFGGTSETLYAPAYVENRALKEAFMQNGTIKETLDRARKADMALVGIGDMNENSYMVELGWFTPQE
IVDASLHQGVTGEIAGYDFFDAQGQPANTVMNDRVIGISTQELRQIPCVIAIAAENTKALALLGALRTGAIDILATSASN
ARTILKMIQHQS

Sequences:

>Translated_332_residues
MISGRGQLSMEKQMIPQDNELLTEIAVSYYQDEMTQEEIAHKFGISRIKVGRLLKRAKTEGIVEINVRYHPVFSTRLEQQ
LIEHFGLKRALIALDYQDEDEQRRQVAALVSAYLATNLKDNTVLAVGQGRNVAAIADHVSVVPERHCKFICGIGGTHRPG
DAINADHISRRLAKKFGGTSETLYAPAYVENRALKEAFMQNGTIKETLDRARKADMALVGIGDMNENSYMVELGWFTPQE
IVDASLHQGVTGEIAGYDFFDAQGQPANTVMNDRVIGISTQELRQIPCVIAIAAENTKALALLGALRTGAIDILATSASN
ARTILKMIQHQS
>Mature_332_residues
MISGRGQLSMEKQMIPQDNELLTEIAVSYYQDEMTQEEIAHKFGISRIKVGRLLKRAKTEGIVEINVRYHPVFSTRLEQQ
LIEHFGLKRALIALDYQDEDEQRRQVAALVSAYLATNLKDNTVLAVGQGRNVAAIADHVSVVPERHCKFICGIGGTHRPG
DAINADHISRRLAKKFGGTSETLYAPAYVENRALKEAFMQNGTIKETLDRARKADMALVGIGDMNENSYMVELGWFTPQE
IVDASLHQGVTGEIAGYDFFDAQGQPANTVMNDRVIGISTQELRQIPCVIAIAAENTKALALLGALRTGAIDILATSASN
ARTILKMIQHQS

Specific function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription. In the presence of AI- 2, lsrR is inactivated by binding phospho-AI-2, leading to the trans

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=318, Percent_Identity=26.7295597484277, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082414, Length=303, Percent_Identity=25.4125412541254, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 36621; Mature: 36621

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISGRGQLSMEKQMIPQDNELLTEIAVSYYQDEMTQEEIAHKFGISRIKVGRLLKRAKTE
CCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
GIVEINVRYHPVFSTRLEQQLIEHFGLKRALIALDYQDEDEQRRQVAALVSAYLATNLKD
CEEEEEEEEECHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCC
NTVLAVGQGRNVAAIADHVSVVPERHCKFICGIGGTHRPGDAINADHISRRLAKKFGGTS
CEEEEECCCCCEEHHHHHHHHCCHHHCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCC
ETLYAPAYVENRALKEAFMQNGTIKETLDRARKADMALVGIGDMNENSYMVELGWFTPQE
CEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCHHH
IVDASLHQGVTGEIAGYDFFDAQGQPANTVMNDRVIGISTQELRQIPCVIAIAAENTKAL
HHHHHHHCCCCCCCCCCEEECCCCCCCCHHCCCEEEECCHHHHHHCCEEEEEECCCCHHH
ALLGALRTGAIDILATSASNARTILKMIQHQS
HHHHHHHHCCEEEEEECCCHHHHHHHHHHCCC
>Mature Secondary Structure
MISGRGQLSMEKQMIPQDNELLTEIAVSYYQDEMTQEEIAHKFGISRIKVGRLLKRAKTE
CCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
GIVEINVRYHPVFSTRLEQQLIEHFGLKRALIALDYQDEDEQRRQVAALVSAYLATNLKD
CEEEEEEEEECHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCC
NTVLAVGQGRNVAAIADHVSVVPERHCKFICGIGGTHRPGDAINADHISRRLAKKFGGTS
CEEEEECCCCCEEHHHHHHHHCCHHHCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCC
ETLYAPAYVENRALKEAFMQNGTIKETLDRARKADMALVGIGDMNENSYMVELGWFTPQE
CEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCHHH
IVDASLHQGVTGEIAGYDFFDAQGQPANTVMNDRVIGISTQELRQIPCVIAIAAENTKAL
HHHHHHHCCCCCCCCCCEEECCCCCCCCHHCCCEEEECCHHHHHHCCEEEEEECCCCHHH
ALLGALRTGAIDILATSASNARTILKMIQHQS
HHHHHHHHCCEEEEEECCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]