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The map label for this gene is erpA [H]

Identifier: 22124714

GI number: 22124714

Start: 897946

End: 898305

Strand: Direct

Name: erpA [H]

Synonym: y0801

Alternate gene names: 22124714

Gene position: 897946-898305 (Clockwise)

Preceding gene: 22124713

Following gene: 22124719

Centisome position: 19.52

GC content: 44.44

Gene sequence:

>360_bases
TTGGGAGTGATGAGGATGAGCAACGAAACAGTACTGCCCCTACAGTTTACCGAGGCGGCGGCAAAGAAAGTTAAACTACT
GATTTCTGATGAGGAAAACCCGAATCTGAAACTGCGTGTTTACATTACCGGTGGTGGATGTAGCGGGTTCCAATATGGTT
TTACTTTTGATGATCAGGTTAATGATGGTGATATGACCATTGAAAAACAAGGTGTTGAGCTGGTTGTTGACCCAATGAGC
CTGCAATATTTAGTGGGCGGTGCCGTGGATTATACTGAAGGGCTGGAAGGTTCTCGTTTTATCGTGACTAACCCGAATGC
AAAGAGTACTTGTGGGTGTGGTTCTTCTTTCAGTATCTAA

Upstream 100 bases:

>100_bases
CTTGAATGAAATACTCAGGTATTAGATAATCGAGCCATAGATCAGGCTGCCAGTGTAGTAACCTGCAACGCGAAGTAGTA
ACCTGCAACTCGAACACCGG

Downstream 100 bases:

>100_bases
TTTACCCTGCGTCCTTGGCGCTACAGCGGTGTTAGCTGCACTTACTTACCTGAATCACTGACCTGTCGTTGGCTTTATAT
AAATAAGCTCATCGGGATTC

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 119; Mature: 118

Protein sequence:

>119_residues
MGVMRMSNETVLPLQFTEAAAKKVKLLISDEENPNLKLRVYITGGGCSGFQYGFTFDDQVNDGDMTIEKQGVELVVDPMS
LQYLVGGAVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI

Sequences:

>Translated_119_residues
MGVMRMSNETVLPLQFTEAAAKKVKLLISDEENPNLKLRVYITGGGCSGFQYGFTFDDQVNDGDMTIEKQGVELVVDPMS
LQYLVGGAVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
>Mature_118_residues
GVMRMSNETVLPLQFTEAAAKKVKLLISDEENPNLKLRVYITGGGCSGFQYGFTFDDQVNDGDMTIEKQGVELVVDPMSL
QYLVGGAVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=83, Percent_Identity=46.9879518072289, Blast_Score=81, Evalue=2e-16,
Organism=Homo sapiens, GI52426768, Length=115, Percent_Identity=32.1739130434783, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786351, Length=114, Percent_Identity=88.5964912280702, Blast_Score=212, Evalue=6e-57,
Organism=Escherichia coli, GI1788877, Length=110, Percent_Identity=38.1818181818182, Blast_Score=72, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=40.7407407407407, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25146411, Length=112, Percent_Identity=30.3571428571429, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193209025, Length=107, Percent_Identity=30.8411214953271, Blast_Score=72, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6323001, Length=106, Percent_Identity=33.0188679245283, Blast_Score=72, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649697, Length=109, Percent_Identity=41.2844036697248, Blast_Score=82, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24642263, Length=110, Percent_Identity=33.6363636363636, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 12844; Mature: 12713

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVMRMSNETVLPLQFTEAAAKKVKLLISDEENPNLKLRVYITGGGCSGFQYGFTFDDQV
CCCEECCCCEEEEEEECCCCCEEEEEEEECCCCCCEEEEEEEECCCCCCEECCEEECCCC
NDGDMTIEKQGVELVVDPMSLQYLVGGAVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
CCCCEEEECCCCEEEECCCEEEEEECCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GVMRMSNETVLPLQFTEAAAKKVKLLISDEENPNLKLRVYITGGGCSGFQYGFTFDDQV
CCEECCCCEEEEEEECCCCCEEEEEEEECCCCCCEEEEEEEECCCCCCEECCEEECCCC
NDGDMTIEKQGVELVVDPMSLQYLVGGAVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
CCCCEEEECCCCEEEECCCEEEEEECCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA