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The map label for this gene is intB [H]

Identifier: 22124662

GI number: 22124662

Start: 835158

End: 836453

Strand: Direct

Name: intB [H]

Synonym: y0749

Alternate gene names: 22124662

Gene position: 835158-836453 (Clockwise)

Preceding gene: 22124661

Following gene: 22124663

Centisome position: 18.15

GC content: 49.23

Gene sequence:

>1296_bases
TTGTACCCACGCAGAACCCTTGAAAGGATACTCAACATGGCTCTGAGTGATGTGAAGGTTCGTACAGCCAAGCCTGAAGC
AAAAGCCTATAAACTTACCGACGGCGAAGGCATGGTGTTACTGGTTCACCCTAACGGCTCGAAATACTGGCGGCTACGCT
ATCGCTTTGACGGTAAAGAAAAGATGTTGGCGTTGGGGAAGTACCCTGAAATATCACTGGCTGATGCCAGGGCACGGCGT
GACGAAGCTCGTAAGCAGTTAGCTAATGGTGTGGACCCAAGTGAGAGCAAGAAAGCCGTTAAGGTAGAGCAGGAGCAAGA
AGCGATAACTTTTGAAGTGGTAGCCAGAGAGTGGCATGCCAGTAATCGTCAATGGTCAGAAGCTCACAGTGCTCGAGTAC
TCAAAAGCTTAGAGGACAATCTCTTTCAAGCCATTGGCAAACGGAATATCGCAGACCTCGGAACCCGTGATCTTTTACCT
CCAATTAAAGCCGTAGAGATGGCTGGACGTCTTCAGGTGGCTTCCCGCCTGCAACAACGAACCACAGCAATAATGCGCTA
TGCAGTTCAAAGCGGTTTAATTGATTACAACCCCGCGCAGGAGATGGCGGGCGCTGTTGCTACCGGTAAAAGAAAGCACC
GCGCTGCACTCGAGTTAAACCGTGTTTCAGAGTTACTTCATCGCATCGACTACTACAGTGGCAGGCCACTCACTCGACTA
GCGGTAGAATTGACTTTATTGGTCTTTATCCGTTCCAGTGAATTACGCTTCGCCCGTTGGTCAGAAGTCGATTTTGAAAC
TGCAATGTGGACGATTCCGGGAGAACGTGAACCACTGGAAGGTGTTAAGCATTCACATCGAGGTTCAAAAATGCGCACTC
CCCATCTTATCCCCTTATCCCGTCAAGCTCTCGCCATTCTGGAAAAGATCAAAAGCATGAGTGGAAACCGTGAGCTGATC
TTTATCGGTGATCACGACCCACGTAAACCGATGAGTGAAAACACGGTAAACAAAGCCCTACGCGTGATGGGATATGACAC
GAAAGTTGAAGTCTGTGGCCACGGTTTCAGAACCATGGCTTGTAGTTCATTGATTGAGTCTGGATTGTGGTCGAGGGATG
CAGTAGAACGGCAGATGAGTCATCAGGAGCGCAACTCTGTGCGTGCGGCTTATATCCATAAAGCCGAGCACTTAGATGAG
CGCAGATTGATGATTCAGTGGTGGGCTGATTACTTGGATGCGAATCGGGAGAAGGGGGTTAGTCCGTTTGATTTTGCGAA
GTTGAATACGAGCTGA

Upstream 100 bases:

>100_bases
GCCTTACCTCTCTTATCAGTCAACATAAGTCAATCTGATTCAATCTACATCAACTTACTGATGTAGGTACATCTGCGGGT
ATATCCCGGTTCGATCATGT

Downstream 100 bases:

>100_bases
TTAAAAAAAGTTTCTGTAAGGCATGTATCTGATATGCCTTATTTTTTCTAATTGTGTTATTTGCGGGCTTTTAACTCAAC
TGTGCCACTACAGATTTTGA

Product: integrase

Products: NA

Alternate protein names: Int(P4) [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MYPRRTLERILNMALSDVKVRTAKPEAKAYKLTDGEGMVLLVHPNGSKYWRLRYRFDGKEKMLALGKYPEISLADARARR
DEARKQLANGVDPSESKKAVKVEQEQEAITFEVVAREWHASNRQWSEAHSARVLKSLEDNLFQAIGKRNIADLGTRDLLP
PIKAVEMAGRLQVASRLQQRTTAIMRYAVQSGLIDYNPAQEMAGAVATGKRKHRAALELNRVSELLHRIDYYSGRPLTRL
AVELTLLVFIRSSELRFARWSEVDFETAMWTIPGEREPLEGVKHSHRGSKMRTPHLIPLSRQALAILEKIKSMSGNRELI
FIGDHDPRKPMSENTVNKALRVMGYDTKVEVCGHGFRTMACSSLIESGLWSRDAVERQMSHQERNSVRAAYIHKAEHLDE
RRLMIQWWADYLDANREKGVSPFDFAKLNTS

Sequences:

>Translated_431_residues
MYPRRTLERILNMALSDVKVRTAKPEAKAYKLTDGEGMVLLVHPNGSKYWRLRYRFDGKEKMLALGKYPEISLADARARR
DEARKQLANGVDPSESKKAVKVEQEQEAITFEVVAREWHASNRQWSEAHSARVLKSLEDNLFQAIGKRNIADLGTRDLLP
PIKAVEMAGRLQVASRLQQRTTAIMRYAVQSGLIDYNPAQEMAGAVATGKRKHRAALELNRVSELLHRIDYYSGRPLTRL
AVELTLLVFIRSSELRFARWSEVDFETAMWTIPGEREPLEGVKHSHRGSKMRTPHLIPLSRQALAILEKIKSMSGNRELI
FIGDHDPRKPMSENTVNKALRVMGYDTKVEVCGHGFRTMACSSLIESGLWSRDAVERQMSHQERNSVRAAYIHKAEHLDE
RRLMIQWWADYLDANREKGVSPFDFAKLNTS
>Mature_431_residues
MYPRRTLERILNMALSDVKVRTAKPEAKAYKLTDGEGMVLLVHPNGSKYWRLRYRFDGKEKMLALGKYPEISLADARARR
DEARKQLANGVDPSESKKAVKVEQEQEAITFEVVAREWHASNRQWSEAHSARVLKSLEDNLFQAIGKRNIADLGTRDLLP
PIKAVEMAGRLQVASRLQQRTTAIMRYAVQSGLIDYNPAQEMAGAVATGKRKHRAALELNRVSELLHRIDYYSGRPLTRL
AVELTLLVFIRSSELRFARWSEVDFETAMWTIPGEREPLEGVKHSHRGSKMRTPHLIPLSRQALAILEKIKSMSGNRELI
FIGDHDPRKPMSENTVNKALRVMGYDTKVEVCGHGFRTMACSSLIESGLWSRDAVERQMSHQERNSVRAAYIHKAEHLDE
RRLMIQWWADYLDANREKGVSPFDFAKLNTS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=404, Percent_Identity=35.1485148514851, Blast_Score=242, Evalue=3e-65,
Organism=Escherichia coli, GI1788690, Length=405, Percent_Identity=33.5802469135802, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI145693166, Length=404, Percent_Identity=34.6534653465347, Blast_Score=226, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 49287; Mature: 49287

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPRRTLERILNMALSDVKVRTAKPEAKAYKLTDGEGMVLLVHPNGSKYWRLRYRFDGKE
CCCHHHHHHHHHHHHHHCEEEECCCCCCEEEEECCCCEEEEEECCCCCEEEEEEEECCHH
KMLALGKYPEISLADARARRDEARKQLANGVDPSESKKAVKVEQEQEAITFEVVAREWHA
HHEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHC
SNRQWSEAHSARVLKSLEDNLFQAIGKRNIADLGTRDLLPPIKAVEMAGRLQVASRLQQR
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHH
TTAIMRYAVQSGLIDYNPAQEMAGAVATGKRKHRAALELNRVSELLHRIDYYSGRPLTRL
HHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
AVELTLLVFIRSSELRFARWSEVDFETAMWTIPGEREPLEGVKHSHRGSKMRTPHLIPLS
HHHHHHHHHHCCCCCCEEECCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCC
RQALAILEKIKSMSGNRELIFIGDHDPRKPMSENTVNKALRVMGYDTKVEVCGHGFRTMA
HHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEHHHCCCHHHHH
CSSLIESGLWSRDAVERQMSHQERNSVRAAYIHKAEHLDERRLMIQWWADYLDANREKGV
HHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCC
SPFDFAKLNTS
CCCCCCCCCCC
>Mature Secondary Structure
MYPRRTLERILNMALSDVKVRTAKPEAKAYKLTDGEGMVLLVHPNGSKYWRLRYRFDGKE
CCCHHHHHHHHHHHHHHCEEEECCCCCCEEEEECCCCEEEEEECCCCCEEEEEEEECCHH
KMLALGKYPEISLADARARRDEARKQLANGVDPSESKKAVKVEQEQEAITFEVVAREWHA
HHEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHC
SNRQWSEAHSARVLKSLEDNLFQAIGKRNIADLGTRDLLPPIKAVEMAGRLQVASRLQQR
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHH
TTAIMRYAVQSGLIDYNPAQEMAGAVATGKRKHRAALELNRVSELLHRIDYYSGRPLTRL
HHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
AVELTLLVFIRSSELRFARWSEVDFETAMWTIPGEREPLEGVKHSHRGSKMRTPHLIPLS
HHHHHHHHHHCCCCCCEEECCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCC
RQALAILEKIKSMSGNRELIFIGDHDPRKPMSENTVNKALRVMGYDTKVEVCGHGFRTMA
HHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEHHHCCCHHHHH
CSSLIESGLWSRDAVERQMSHQERNSVRAAYIHKAEHLDERRLMIQWWADYLDANREKGV
HHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCC
SPFDFAKLNTS
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]