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The map label for this gene is hfq [H]

Identifier: 22124544

GI number: 22124544

Start: 713304

End: 713609

Strand: Direct

Name: hfq [H]

Synonym: y0630

Alternate gene names: 22124544

Gene position: 713304-713609 (Clockwise)

Preceding gene: 22124543

Following gene: 22124545

Centisome position: 15.5

GC content: 46.08

Gene sequence:

>306_bases
ATGGCTAAGGGGCAATCTTTGCAAGATCCGTTCCTGAACGCATTGCGTCGTGAACGGGTTCCGGTTTCTATTTATTTAGT
GAATGGTATTAAACTGCAGGGCCAAGTTGAGTCTTTTGATCAGTTTGTCATTCTGTTAAAAAATACAGTCAGCCAGATGG
TTTATAAGCACGCCATCTCTACTGTTGTGCCTTCTCGTCCGGTTTCGCATCACAGCAATACTCCGAGCGGTAGCACCAAT
AATTATCATGGTAGTAATCCGTCTGCGCCGCAACAGCCGCAGCAGGACAGTGATGACGCTGAATAA

Upstream 100 bases:

>100_bases
ACAATTGATTAGTACTCAACGCACAGATTTTTTTACGCAGTTTATTTTCGAGCCGATAGGTTCTTAGTTAAAAACAACAA
GCAAATAAGGAAAATATAGA

Downstream 100 bases:

>100_bases
AGCCCATTGCTGGTCGACCATGATGGAGAACATAAGCAACGGATTCAAGCTTATGTTCTCCGCACTAGCGGCTTTGATCC
GTTTGAGAGGTTGCACGTTT

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: HF-1; Host factor-I protein; HF-I [H]

Number of amino acids: Translated: 101; Mature: 100

Protein sequence:

>101_residues
MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQVESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNTPSGSTN
NYHGSNPSAPQQPQQDSDDAE

Sequences:

>Translated_101_residues
MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQVESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNTPSGSTN
NYHGSNPSAPQQPQQDSDDAE
>Mature_100_residues
AKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQVESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNTPSGSTNN
YHGSNPSAPQQPQQDSDDAE

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=102, Percent_Identity=80.3921568627451, Blast_Score=166, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 11131; Mature: 10999

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQVESFDQFVILLKNTVSQMVYKHAIS
CCCCCCCCCHHHHHHHHCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
TVVPSRPVSHHSNTPSGSTNNYHGSNPSAPQQPQQDSDDAE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQVESFDQFVILLKNTVSQMVYKHAIS
CCCCCCCCHHHHHHHHCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
TVVPSRPVSHHSNTPSGSTNNYHGSNPSAPQQPQQDSDDAE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA