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The map label for this gene is rpoC [H]

Identifier: 22124400

GI number: 22124400

Start: 544195

End: 548451

Strand: Direct

Name: rpoC [H]

Synonym: y0485

Alternate gene names: 22124400

Gene position: 544195-548451 (Clockwise)

Preceding gene: 22124399

Following gene: 22124408

Centisome position: 11.83

GC content: 51.19

Gene sequence:

>4257_bases
GTGCCTATCAGGTCTAACTCCGACAGGAGCCAATCCGTGAAAGACTTATTAAAGTTTCTGAAAGCGCAAACTAAGACCGA
AGAGTTTGATGCGATCAAAATTGCTCTGGCATCGCCAGACATGATCCGTTCATGGTCATTCGGTGAAGTTAAAAAGCCGG
AAACCATTAACTACCGTACGTTCAAACCAGAACGTGACGGCCTTTTCTGCGCCCGTATCTTTGGCCCAGTAAAAGATTAC
GAATGCCTGTGCGGTAAGTACAAGCGTTTAAAACACCGTGGTGTTATTTGTGAGAAATGCGGCGTTGAAGTGACTCAAAC
TAAAGTGCGCCGTGAGCGTATGGGTCACATCGAACTGGCTTCTCCAACTGCGCACATCTGGTTCCTGAAATCGCTGCCAT
CTCGTATCGGTTTGCTGCTGGATATGCCATTACGTGACATCGAACGTGTACTGTACTTCGAATCCTATGTGGTTATTGAA
GGCGGTATGACCAACCTGGAACGTCGCCAGATTCTGACTGAAGAGCAGTATCTGGATGCGTTGGAAGAGTTTGGTGATGA
GTTCGACGCGAAAATGGGCGCCGAGGCTATTCAGGCCCTGTTGAAAAACATGGATCTGGAAGCTGAGTGCGAGATCCTGC
GTGAAGAATTGAACGAAACAAATTCTGAAACCAAGCGTAAGAAACTGACCAAGCGTATCAAGTTGCTGGAAGCGTTCGTA
CAGTCTGGCAACAAGCCAGAGTGGATGATCCTGACCGTGCTGCCTGTGTTGCCGCCAGATCTGCGTCCATTGGTTCCGTT
GGATGGTGGTCGCTTTGCGACTTCCGATCTGAACGATTTGTATCGTCGCGTGATCAACCGTAACAACCGTCTGAAACGCC
TGCTGGACTTGGCGGCACCGGACATCATCGTACGTAACGAAAAGCGTATGCTGCAAGAAGCAGTAGATGCATTGCTGGAT
AACGGCCGTCGCGGTCGTGCGATTACCGGCTCTAACAAGCGTCCGTTGAAGTCACTGGCTGACATGATCAAAGGTAAGCA
AGGTCGTTTCCGTCAGAACTTGCTGGGTAAACGTGTTGACTACTCAGGTCGTTCGGTTATCACCGTTGGTCCATACCTGC
GTCTGCATCAGTGCGGTCTGCCTAAGAAAATGGCTCTTGAGCTGTTTAAACCGTTCATCTACGGCAAGCTGGAATTGCGT
GGTCTTGCTACCACCATCAAAGCCGCCAAGAAGATGGTTGAGCGTGAAGAAGCGGTTGTTTGGGATATCCTGGATGAAGT
TATCCGCGAACACCCAGTGCTGCTGAACCGTGCACCAACCCTTCACCGTTTGGGTATCCAGGCGTTTGAACCGGTTCTGA
TCGAAGGTAAGGCAATCCAGTTGCACCCATTGGTTTGTGCGGCATATAACGCCGACTTCGATGGTGACCAAATGGCTGTC
CACGTACCGCTGACACTGGAAGCTCAGTTAGAAGCGCGTGCGTTAATGATGTCTACCAACAACATCCTGTCACCCGCGAA
CGGCGAGCCAATCATCGTTCCTTCTCAGGACGTTGTATTGGGTCTGTACTACATGACCCGCGACTGTGTTAACGCCAAAG
GCGAAGGCATGGTTCTGACTGGCCCGAAAGAAGCTGAGCGTATTTATCGCGCTGGCTTGGCATCTCTGCATGCCCGCGTA
AAAGTACGTATTACCGAAGAAATTCGTAATACCGAAGGCGAAAGCATTACGCGTACCAGCATTATCGATACGACTGTAGG
CCGTGCTATTTTGTGGATGATCGTCCCGCAAGGCCTGCCTTACTCTATCGTTAACCAGCCGCTGGGTAAAAAAGCTATCT
CTAAGATGCTGAACACGTGTTACCGCATCTTGGGCTTGAAGCCAACGGTTATCTTTGCTGACCAGATCATGTACACCGGT
TTTGCTTACGCAGCACGCTCAGGCGCCTCTGTAGGTATCGATGACATGGTTATCCCAGAAGCGAAAGCGGGGATCATCGA
AGAAGCTGAAACTGAAGTTGCTGAGATCCAAGAACAGTTCCAATCTGGTCTGGTCACGGCAGGCGAACGTTATAACAAAG
TGATCGATATCTGGGCTGCGGCTAACGAACGTGTTGCTAAAGCGATGATGGATAACTTGTCGGTTGAGGATGTTGTCAAC
CGTGATGGCGTTGTTGAACAGCAAGTTTCATTCAACAGCATCTTCATGATGGCCGACTCCGGTGCGCGTGGTTCTGCCGC
ACAGATTCGTCAGCTGGCAGGTATGCGTGGTCTGATGGCTAAGCCAGACGGCTCGATCATTGAAACGCCAATCACCGCGA
ACTTCCGTGAAGGTTTGAACGTACTTCAGTACTTCATCTCAACCCACGGTGCGCGTAAAGGTTTGGCGGATACCGCATTG
AAAACTGCGAACTCCGGTTACCTGACCCGTCGTTTAGTTGACGTGGCACAGGATCTGGTGGTGACTGAGGATGATTGTGG
TACCCATAACGGTATCGTGATGACCCCGGTTATCGAAGGTGGTGATGTTAAAGAGCCACTGCGTGATCGCGTACTGGGTC
GTGTGACTGCAGAAGAAGTTATCAAGCCAGGTTCGGCTGATATTCTGGTTCCGCGTAACACCCTGCTGGACGAAAAATGG
TGTGATCTGTTAGAAGAAAACTCCGTCGACAGCGTTAAAGTTCGCTCCGTAGTAAGCTGTGAAACTGATTTCGGTGTGTG
TGCTAACTGCTATGGTCGCGACCTGGCACGTGGCCACATCATCAACAAAGGTGAAGCGGTTGGTGTTATTGCAGCACAGT
CCATCGGTGAGCCGGGTACTCAGCTTACGATGCGTACGTTCCACATCGGTGGTGCGGCATCTCGTGCGGCAGCAGAATCC
AGCATCCAGGTTAAGAACAAAGGCAGCTTGAAACTGAGCAACGTCAAGTTCGTGACCAATGCGGCTGGCAAGCTGGTTAT
TACGTCTCGTAATACCGAGCTGAAGCTGATCGACGAATTCGGTCGTACCAAAGAAAGCTATAAAGTGCCTTACGGTGCGG
TAATGGCTAAAGGCGATGGCGCAGAAGTTCAGGGCGGCGAAACCGTTGCTAACTGGGATCCGCACATCATGCCAGTGGTC
ACCGAAGTGAGCGGCTTCATTCGCTTCGCCGACATGGTTGATGGCCAGACCATTACTCGCCAGACCGACGAACTGACTGG
TTTGTCTTCTCTGGTCGTTCTGGACAGTGCAGAGCGTACGGGTAGCGGTAAAGACCTGCGTCCAGCACTGAAAATCGTTG
ATGCCAAAGGCAATGACGTATTGATCCCAGGTACTGATATGCCTGCTCAATACTTCCTGCCAGGTAAAGCGATTGTACAG
CTGGAAGACGGTATTCAGATCGGTGCGGGTGATACCTTGGCGCGTATTCCTCAGGAATCAAGCGGTACCAAGGATATTAC
CGGTGGTCTGCCACGTGTTGCTGACTTGTTCGAAGCACGTCGTCCGAAAGAGCCTGCAATCCTGGCTGAAATCAGCGGGA
TCATCTCGTTCGGTAAAGAGACCAAAGGCAAGCGTCGTCTGGTGATCTCACCGTTGGATGGTAGCGATGCATACGAAGAG
ATGATTCCGAAATGGCGTCAGCTTAACGTGTTCGAAGGTGAAGTTGTGGAACGCGGTGACGTGGTTTCCGATGGCCCAGA
ATCTCCACATGACATTCTGCGTCTGCGTGGCGTTCACGCGGTTACCCGCTACATCACCAACGAAGTGCAGGAAGTTTACC
GTCTGCAAGGCGTTAAGATTAACGATAAACACATTGAAGTTATCGTTCGTCAGATGCTGCGTAAAGGCACTATCGTTGAT
GCAGGTAGCACCGACTTCCTGGAAGGCGAGCAGGCAGAAATGTCCCGCGTTAAAATCGCTAACCGTAAGCTGGCAGCAGA
AGGCAAAATTGAGGCTACGTTCACTCGTGACCTGCTGGGTATCACCAAGGCATCCTTGGCGACCGAGTCCTTCATCTCTG
CGGCTTCGTTCCAGGAAACCACGCGCGTTCTTACTGAAGCGGCAGTTGCCGGTAAACGTGATGAATTGCGTGGCCTGAAA
GAAAACGTAATCGTGGGCCGTCTGATCCCAGCCGGTACCGGTTATGCTTATCATCAGGACCGTATGCGCCGTAAAGCACA
GGGTGAAGCGCCTGTTGTTCCACAAGTCAGCGCGGATGAAGCGACTGCAAACTTGGCCGAATTGCTTAATGCCGGTTTTG
GTAACAACAAAGGCTAA

Upstream 100 bases:

>100_bases
AAGAGTAATTCTTCACCAGACGGCAAACTCTCATAGCCGGGAGTTTGCTGGTGGTTCGCACTGGTCACAGGGGCACTCAA
ACCTAGGTTCTTAGGTTTGA

Downstream 100 bases:

>100_bases
TCTCTTTGCCTACTACCAAATAAATATCCTCCGGCATAGCCGGAGGTTTTTCATATGCGCCTATAAGGCTCTGTTACCAG
CCGCGCCCTAACAGGCGCAT

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1418; Mature: 1417

Protein sequence:

>1418_residues
MPIRSNSDRSQSVKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDY
ECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIE
GGMTNLERRQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKNMDLEAECEILREELNETNSETKRKKLTKRIKLLEAFV
QSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLD
NGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELR
GLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAV
HVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERIYRAGLASLHARV
KVRITEEIRNTEGESITRTSIIDTTVGRAILWMIVPQGLPYSIVNQPLGKKAISKMLNTCYRILGLKPTVIFADQIMYTG
FAYAARSGASVGIDDMVIPEAKAGIIEEAETEVAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMDNLSVEDVVN
RDGVVEQQVSFNSIFMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTAL
KTANSGYLTRRLVDVAQDLVVTEDDCGTHNGIVMTPVIEGGDVKEPLRDRVLGRVTAEEVIKPGSADILVPRNTLLDEKW
CDLLEENSVDSVKVRSVVSCETDFGVCANCYGRDLARGHIINKGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAES
SIQVKNKGSLKLSNVKFVTNAAGKLVITSRNTELKLIDEFGRTKESYKVPYGAVMAKGDGAEVQGGETVANWDPHIMPVV
TEVSGFIRFADMVDGQTITRQTDELTGLSSLVVLDSAERTGSGKDLRPALKIVDAKGNDVLIPGTDMPAQYFLPGKAIVQ
LEDGIQIGAGDTLARIPQESSGTKDITGGLPRVADLFEARRPKEPAILAEISGIISFGKETKGKRRLVISPLDGSDAYEE
MIPKWRQLNVFEGEVVERGDVVSDGPESPHDILRLRGVHAVTRYITNEVQEVYRLQGVKINDKHIEVIVRQMLRKGTIVD
AGSTDFLEGEQAEMSRVKIANRKLAAEGKIEATFTRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLK
ENVIVGRLIPAGTGYAYHQDRMRRKAQGEAPVVPQVSADEATANLAELLNAGFGNNKG

Sequences:

>Translated_1418_residues
MPIRSNSDRSQSVKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDY
ECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIE
GGMTNLERRQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKNMDLEAECEILREELNETNSETKRKKLTKRIKLLEAFV
QSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLD
NGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELR
GLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAV
HVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERIYRAGLASLHARV
KVRITEEIRNTEGESITRTSIIDTTVGRAILWMIVPQGLPYSIVNQPLGKKAISKMLNTCYRILGLKPTVIFADQIMYTG
FAYAARSGASVGIDDMVIPEAKAGIIEEAETEVAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMDNLSVEDVVN
RDGVVEQQVSFNSIFMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTAL
KTANSGYLTRRLVDVAQDLVVTEDDCGTHNGIVMTPVIEGGDVKEPLRDRVLGRVTAEEVIKPGSADILVPRNTLLDEKW
CDLLEENSVDSVKVRSVVSCETDFGVCANCYGRDLARGHIINKGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAES
SIQVKNKGSLKLSNVKFVTNAAGKLVITSRNTELKLIDEFGRTKESYKVPYGAVMAKGDGAEVQGGETVANWDPHIMPVV
TEVSGFIRFADMVDGQTITRQTDELTGLSSLVVLDSAERTGSGKDLRPALKIVDAKGNDVLIPGTDMPAQYFLPGKAIVQ
LEDGIQIGAGDTLARIPQESSGTKDITGGLPRVADLFEARRPKEPAILAEISGIISFGKETKGKRRLVISPLDGSDAYEE
MIPKWRQLNVFEGEVVERGDVVSDGPESPHDILRLRGVHAVTRYITNEVQEVYRLQGVKINDKHIEVIVRQMLRKGTIVD
AGSTDFLEGEQAEMSRVKIANRKLAAEGKIEATFTRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLK
ENVIVGRLIPAGTGYAYHQDRMRRKAQGEAPVVPQVSADEATANLAELLNAGFGNNKG
>Mature_1417_residues
PIRSNSDRSQSVKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYE
CLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEG
GMTNLERRQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKNMDLEAECEILREELNETNSETKRKKLTKRIKLLEAFVQ
SGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDN
GRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRG
LATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVH
VPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERIYRAGLASLHARVK
VRITEEIRNTEGESITRTSIIDTTVGRAILWMIVPQGLPYSIVNQPLGKKAISKMLNTCYRILGLKPTVIFADQIMYTGF
AYAARSGASVGIDDMVIPEAKAGIIEEAETEVAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMDNLSVEDVVNR
DGVVEQQVSFNSIFMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALK
TANSGYLTRRLVDVAQDLVVTEDDCGTHNGIVMTPVIEGGDVKEPLRDRVLGRVTAEEVIKPGSADILVPRNTLLDEKWC
DLLEENSVDSVKVRSVVSCETDFGVCANCYGRDLARGHIINKGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESS
IQVKNKGSLKLSNVKFVTNAAGKLVITSRNTELKLIDEFGRTKESYKVPYGAVMAKGDGAEVQGGETVANWDPHIMPVVT
EVSGFIRFADMVDGQTITRQTDELTGLSSLVVLDSAERTGSGKDLRPALKIVDAKGNDVLIPGTDMPAQYFLPGKAIVQL
EDGIQIGAGDTLARIPQESSGTKDITGGLPRVADLFEARRPKEPAILAEISGIISFGKETKGKRRLVISPLDGSDAYEEM
IPKWRQLNVFEGEVVERGDVVSDGPESPHDILRLRGVHAVTRYITNEVQEVYRLQGVKINDKHIEVIVRQMLRKGTIVDA
GSTDFLEGEQAEMSRVKIANRKLAAEGKIEATFTRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKE
NVIVGRLIPAGTGYAYHQDRMRRKAQGEAPVVPQVSADEATANLAELLNAGFGNNKG

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=915, Percent_Identity=25.6830601092896, Blast_Score=197, Evalue=5e-50,
Organism=Homo sapiens, GI39725938, Length=308, Percent_Identity=31.4935064935065, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI103471997, Length=598, Percent_Identity=27.257525083612, Blast_Score=135, Evalue=2e-31,
Organism=Escherichia coli, GI2367335, Length=1404, Percent_Identity=92.8062678062678, Blast_Score=2679, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=560, Percent_Identity=26.25, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI25145495, Length=319, Percent_Identity=31.6614420062696, Blast_Score=149, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6324690, Length=761, Percent_Identity=26.0183968462549, Blast_Score=174, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6320061, Length=668, Percent_Identity=26.0479041916168, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI17530899, Length=841, Percent_Identity=25.089179548157, Blast_Score=183, Evalue=1e-45,
Organism=Drosophila melanogaster, GI281360912, Length=322, Percent_Identity=29.8136645962733, Blast_Score=133, Evalue=7e-31,
Organism=Drosophila melanogaster, GI17647875, Length=328, Percent_Identity=28.6585365853659, Blast_Score=101, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 156234; Mature: 156103

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRSNSDRSQSVKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRT
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHCCCCCCCCCCCCCCEEE
FKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELA
CCCCCCCEEEEHHHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEEC
SPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERRQILTEEQYLDA
CCCEEEHHHHHHHHHHCEEECCCHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHH
LEEFGDEFDAKMGAEAIQALLKNMDLEAECEILREELNETNSETKRKKLTKRIKLLEAFV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAP
HCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCC
DIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVD
CEEEECHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCC
YSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVV
CCCCEEEEECCCHHHHHCCCCHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHHHHH
WDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAV
HHHHHHHHHHCCEEECCCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCCEEE
HVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLT
EEEEEEECCHHHHHHEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEEEE
GPKEAERIYRAGLASLHARVKVRITEEIRNTEGESITRTSIIDTTVGRAILWMIVPQGLP
CCHHHHHHHHHHHHHHHHEEEEEEHHHHCCCCCCCEEHHHHHHHHHHHHEEEHCCCCCCC
YSIVNQPLGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPE
HHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCEECCC
AKAGIIEEAETEVAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMDNLSVEDVVN
HHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHEEEEEHHCHHHHHHHHHHCCCHHHHHC
RDGVVEQQVSFNSIFMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLN
CCCCCHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHH
VLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHNGIVMTPVIEG
HHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCEEEEEEECC
GDVKEPLRDRVLGRVTAEEVIKPGSADILVPRNTLLDEKWCDLLEENSVDSVKVRSVVSC
CCCCHHHHHHHHHHCCHHHHHCCCCCCEEECCHHHCCHHHHHHHHCCCCCCEEHHHEEEC
ETDFGVCANCYGRDLARGHIINKGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAES
CCCCCHHHHHHCCHHHCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCHHHHHCCC
SIQVKNKGSLKLSNVKFVTNAAGKLVITSRNTELKLIDEFGRTKESYKVPYGAVMAKGDG
CEEEECCCCEEEECEEEEECCCCEEEEEECCCCEEEHHHHCCCCHHCCCCCCEEEECCCC
AEVQGGETVANWDPHIMPVVTEVSGFIRFADMVDGQTITRQTDELTGLSSLVVLDSAERT
CCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHCCCEEEEEEECCCCC
GSGKDLRPALKIVDAKGNDVLIPGTDMPAQYFLPGKAIVQLEDGIQIGAGDTLARIPQES
CCCCCCCCCCEEEECCCCEEEECCCCCCCEEECCCCEEEEEECCEEECCCCHHHHCCCCC
SGTKDITGGLPRVADLFEARRPKEPAILAEISGIISFGKETKGKRRLVISPLDGSDAYEE
CCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHH
MIPKWRQLNVFEGEVVERGDVVSDGPESPHDILRLRGVHAVTRYITNEVQEVYRLQGVKI
HCCHHHCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
NDKHIEVIVRQMLRKGTIVDAGSTDFLEGEQAEMSRVKIANRKLAAEGKIEATFTRDLLG
CHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHCCEECCCCCEEEHHHHHHHH
ITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHCCEEEEEECCCCCCHHHHH
RMRRKAQGEAPVVPQVSADEATANLAELLNAGFGNNKG
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PIRSNSDRSQSVKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRT
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHCCCCCCCCCCCCCCEEE
FKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELA
CCCCCCCEEEEHHHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEEC
SPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERRQILTEEQYLDA
CCCEEEHHHHHHHHHHCEEECCCHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHH
LEEFGDEFDAKMGAEAIQALLKNMDLEAECEILREELNETNSETKRKKLTKRIKLLEAFV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAP
HCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCC
DIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVD
CEEEECHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCC
YSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVV
CCCCEEEEECCCHHHHHCCCCHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHHHHH
WDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAV
HHHHHHHHHHCCEEECCCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCCEEE
HVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLT
EEEEEEECCHHHHHHEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEEEE
GPKEAERIYRAGLASLHARVKVRITEEIRNTEGESITRTSIIDTTVGRAILWMIVPQGLP
CCHHHHHHHHHHHHHHHHEEEEEEHHHHCCCCCCCEEHHHHHHHHHHHHEEEHCCCCCCC
YSIVNQPLGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPE
HHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCEECCC
AKAGIIEEAETEVAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMDNLSVEDVVN
HHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHEEEEEHHCHHHHHHHHHHCCCHHHHHC
RDGVVEQQVSFNSIFMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLN
CCCCCHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHH
VLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHNGIVMTPVIEG
HHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCEEEEEEECC
GDVKEPLRDRVLGRVTAEEVIKPGSADILVPRNTLLDEKWCDLLEENSVDSVKVRSVVSC
CCCCHHHHHHHHHHCCHHHHHCCCCCCEEECCHHHCCHHHHHHHHCCCCCCEEHHHEEEC
ETDFGVCANCYGRDLARGHIINKGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAES
CCCCCHHHHHHCCHHHCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCHHHHHCCC
SIQVKNKGSLKLSNVKFVTNAAGKLVITSRNTELKLIDEFGRTKESYKVPYGAVMAKGDG
CEEEECCCCEEEECEEEEECCCCEEEEEECCCCEEEHHHHCCCCHHCCCCCCEEEECCCC
AEVQGGETVANWDPHIMPVVTEVSGFIRFADMVDGQTITRQTDELTGLSSLVVLDSAERT
CCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHCCCEEEEEEECCCCC
GSGKDLRPALKIVDAKGNDVLIPGTDMPAQYFLPGKAIVQLEDGIQIGAGDTLARIPQES
CCCCCCCCCCEEEECCCCEEEECCCCCCCEEECCCCEEEEEECCEEECCCCHHHHCCCCC
SGTKDITGGLPRVADLFEARRPKEPAILAEISGIISFGKETKGKRRLVISPLDGSDAYEE
CCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHH
MIPKWRQLNVFEGEVVERGDVVSDGPESPHDILRLRGVHAVTRYITNEVQEVYRLQGVKI
HCCHHHCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
NDKHIEVIVRQMLRKGTIVDAGSTDFLEGEQAEMSRVKIANRKLAAEGKIEATFTRDLLG
CHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHCCEECCCCCEEEHHHHHHHH
ITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHCCEEEEEECCCCCCHHHHH
RMRRKAQGEAPVVPQVSADEATANLAELLNAGFGNNKG
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA