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The map label for this gene is hasE [H]

Identifier: 22124233

GI number: 22124233

Start: 342749

End: 344077

Strand: Direct

Name: hasE [H]

Synonym: y0316

Alternate gene names: 22124233

Gene position: 342749-344077 (Clockwise)

Preceding gene: 22124232

Following gene: 22124234

Centisome position: 7.45

GC content: 48.68

Gene sequence:

>1329_bases
ATGTTGCCTGAATCAGTCTGTTATTCGGTTGCGAATGCCAATCGCCAACCACCACTCCAAATAAACAGTGGGCGCTATCT
CAATATAGGTGGGGGGCTGGTCGTTATCGGCTTCATCGGCTTTTTACTTTGGGCGGGGTTAGCGCCGTTAGATAAAGGCG
TTGCCGTGACCGGGCTGCTTGTGGTGGCAGAAAACCGCAAAGTGATCCAGCCGCTGCAAGGGGGGCGTATTCAGCAACTG
CATGTCACTGAAGGCGACGAAATAGTGTCTGGGCAATTATTGGTCACGCTGGATGACACGGCGATACGCAATCAGCGGGA
TAATTTACAGCATCAGTATCTAAGCGCCCTTGCTCAGGAAGCACGTTTAACTGCTGAGCAAAACGATCTGGATGTGATCA
CTTTCCCGCAGGCGCTGCTTGAGCACGCAACACAACCAGCGGTTGAACGTAATATTATTTTGCAGCAACAGCTTTTACAT
CACCGCCGCCAGGCGCACTTGAGTGAAATCGCCCGGTTATCGACACAGCTCACTCGCCATCAGGCTCGGCTCGATGGGTT
GCAAGCTATGCGGAGCAATCATCAACGTCAATCCAATTTATTCCAGCAACAATTAGACAGTGTGCAGTTATTGGCAAAGG
ATGGTCATATTGCCAAAAATAAATTGTTAGAAATGGAAAGCCAGTCAACCTCACTCCAGGCACGAGTAGAACAAAGTACC
AGCGATATTGCGGAAGCACATAAGCTTATCGATGAAACAGAACAACATGTTTTACAACGGCGCGAACAATATCAAAGTGA
GAATAGCGAGCAATTAGCCAAGGCACAGCAAAACACCCAAGAACTGGTCCAACGTTTAAATATTGCAGAATATGAATTGA
GTCATACCCGTATTTTTGCACCAGTCAGTGGTTCAGTTATCGCATTGGCTCAACACACTGTGGGGGGCGTAGTAAGCTCA
GGGCAGGCATTAATGGAAATTGTCCCCAGTGGGCAGCCGTTATTCGTTGAGGCTCAGTTGCCGGTGGAGCTAATTGATAA
GGTTGCGGTCGGGCTACCTGTAGATCTCAATTTTTCTGCGTTTAATCAAAGTAATACCCCCCGGCTACAAGGCTCTGTAT
GGCGCATCGGAGCCGATCGTATACAACCCCCACCTACTTCACCGCCTTATTACCCTTTAACCGTTGCGATTGATCTTGAC
CCGACGGAACTGGCAATCCGTCCAGGTATGGCCGTTGATGTTTTTATACGTACCGGAGAAAGGTCATTACTCAGCTATTT
ATTTAAGCCATTCACTGATCGCCTGCACCTCGCGTTAGCCGAGGAATAA

Upstream 100 bases:

>100_bases
TACTACATCATCACCGAAGCCATGATCACCAAAACCCTTATCACAAAAAACCTCATCACAAAAACTGTGACCATAAAAAC
CAGGGATGGAGATATAACCG

Downstream 100 bases:

>100_bases
AATATCTCGGTTAAGTCATTGGAAATAAAACATTAAAAATAAAGGAATATAATGATTTCTTATCATGAATAGATTACAGC
AGAGCAGTGACAAACTTATA

Product: HlyD family secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MLPESVCYSVANANRQPPLQINSGRYLNIGGGLVVIGFIGFLLWAGLAPLDKGVAVTGLLVVAENRKVIQPLQGGRIQQL
HVTEGDEIVSGQLLVTLDDTAIRNQRDNLQHQYLSALAQEARLTAEQNDLDVITFPQALLEHATQPAVERNIILQQQLLH
HRRQAHLSEIARLSTQLTRHQARLDGLQAMRSNHQRQSNLFQQQLDSVQLLAKDGHIAKNKLLEMESQSTSLQARVEQST
SDIAEAHKLIDETEQHVLQRREQYQSENSEQLAKAQQNTQELVQRLNIAEYELSHTRIFAPVSGSVIALAQHTVGGVVSS
GQALMEIVPSGQPLFVEAQLPVELIDKVAVGLPVDLNFSAFNQSNTPRLQGSVWRIGADRIQPPPTSPPYYPLTVAIDLD
PTELAIRPGMAVDVFIRTGERSLLSYLFKPFTDRLHLALAEE

Sequences:

>Translated_442_residues
MLPESVCYSVANANRQPPLQINSGRYLNIGGGLVVIGFIGFLLWAGLAPLDKGVAVTGLLVVAENRKVIQPLQGGRIQQL
HVTEGDEIVSGQLLVTLDDTAIRNQRDNLQHQYLSALAQEARLTAEQNDLDVITFPQALLEHATQPAVERNIILQQQLLH
HRRQAHLSEIARLSTQLTRHQARLDGLQAMRSNHQRQSNLFQQQLDSVQLLAKDGHIAKNKLLEMESQSTSLQARVEQST
SDIAEAHKLIDETEQHVLQRREQYQSENSEQLAKAQQNTQELVQRLNIAEYELSHTRIFAPVSGSVIALAQHTVGGVVSS
GQALMEIVPSGQPLFVEAQLPVELIDKVAVGLPVDLNFSAFNQSNTPRLQGSVWRIGADRIQPPPTSPPYYPLTVAIDLD
PTELAIRPGMAVDVFIRTGERSLLSYLFKPFTDRLHLALAEE
>Mature_442_residues
MLPESVCYSVANANRQPPLQINSGRYLNIGGGLVVIGFIGFLLWAGLAPLDKGVAVTGLLVVAENRKVIQPLQGGRIQQL
HVTEGDEIVSGQLLVTLDDTAIRNQRDNLQHQYLSALAQEARLTAEQNDLDVITFPQALLEHATQPAVERNIILQQQLLH
HRRQAHLSEIARLSTQLTRHQARLDGLQAMRSNHQRQSNLFQQQLDSVQLLAKDGHIAKNKLLEMESQSTSLQARVEQST
SDIAEAHKLIDETEQHVLQRREQYQSENSEQLAKAQQNTQELVQRLNIAEYELSHTRIFAPVSGSVIALAQHTVGGVVSS
GQALMEIVPSGQPLFVEAQLPVELIDKVAVGLPVDLNFSAFNQSNTPRLQGSVWRIGADRIQPPPTSPPYYPLTVAIDLD
PTELAIRPGMAVDVFIRTGERSLLSYLFKPFTDRLHLALAEE

Specific function: Involved in the secretion of proteases A, B, C and G [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 48988; Mature: 48988

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPESVCYSVANANRQPPLQINSGRYLNIGGGLVVIGFIGFLLWAGLAPLDKGVAVTGLL
CCCHHHHHHHHCCCCCCCEEECCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEEEE
VVAENRKVIQPLQGGRIQQLHVTEGDEIVSGQLLVTLDDTAIRNQRDNLQHQYLSALAQE
EEECCCHHCCCCCCCCEEEEEECCCCCEECCEEEEEECCHHHHCHHHHHHHHHHHHHHHH
ARLTAEQNDLDVITFPQALLEHATQPAVERNIILQQQLLHHRRQAHLSEIARLSTQLTRH
HHHCCCCCCCEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QARLDGLQAMRSNHQRQSNLFQQQLDSVQLLAKDGHIAKNKLLEMESQSTSLQARVEQST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHH
SDIAEAHKLIDETEQHVLQRREQYQSENSEQLAKAQQNTQELVQRLNIAEYELSHTRIFA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHEEECCCEEEE
PVSGSVIALAQHTVGGVVSSGQALMEIVPSGQPLFVEAQLPVELIDKVAVGLPVDLNFSA
CCCCCEEEEEHHHHHHHHHCCHHHHHHCCCCCCEEEEECCCHHHHHHHHHCCCCCCCHHH
FNQSNTPRLQGSVWRIGADRIQPPPTSPPYYPLTVAIDLDPTELAIRPGMAVDVFIRTGE
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEECCCHHEEECCCCEEEEEEECCH
RSLLSYLFKPFTDRLHLALAEE
HHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MLPESVCYSVANANRQPPLQINSGRYLNIGGGLVVIGFIGFLLWAGLAPLDKGVAVTGLL
CCCHHHHHHHHCCCCCCCEEECCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEEEE
VVAENRKVIQPLQGGRIQQLHVTEGDEIVSGQLLVTLDDTAIRNQRDNLQHQYLSALAQE
EEECCCHHCCCCCCCCEEEEEECCCCCEECCEEEEEECCHHHHCHHHHHHHHHHHHHHHH
ARLTAEQNDLDVITFPQALLEHATQPAVERNIILQQQLLHHRRQAHLSEIARLSTQLTRH
HHHCCCCCCCEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QARLDGLQAMRSNHQRQSNLFQQQLDSVQLLAKDGHIAKNKLLEMESQSTSLQARVEQST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHH
SDIAEAHKLIDETEQHVLQRREQYQSENSEQLAKAQQNTQELVQRLNIAEYELSHTRIFA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHEEECCCEEEE
PVSGSVIALAQHTVGGVVSSGQALMEIVPSGQPLFVEAQLPVELIDKVAVGLPVDLNFSA
CCCCCEEEEEHHHHHHHHHCCHHHHHHCCCCCCEEEEECCCHHHHHHHHHCCCCCCCHHH
FNQSNTPRLQGSVWRIGADRIQPPPTSPPYYPLTVAIDLDPTELAIRPGMAVDVFIRTGE
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEECCCHHEEECCCCEEEEEEECCH
RSLLSYLFKPFTDRLHLALAEE
HHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2184029 [H]