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The map label for this gene is insK [H]

Identifier: 22124201

GI number: 22124201

Start: 302949

End: 303569

Strand: Direct

Name: insK [H]

Synonym: y0283

Alternate gene names: 22124201

Gene position: 302949-303569 (Clockwise)

Preceding gene: 22124200

Following gene: 22124202

Centisome position: 6.58

GC content: 48.63

Gene sequence:

>621_bases
TTGGCACGCAGTACATACTATTATCATGCATCGAAACCGGACGGTGTAATTGATGACTATGCAGATGCGGTAAAAGCGAT
TGGCGCCCTAAGCAGACGACACGCACAGCGCTACGGTTATCGCCGGATGACGGTCGCACTGAGAAAAGAAGGGTTCACAC
TGAATCACAAAACGGTGCGAAAACTGATGAATCAGCACGGGTTACTCAGCCTCATTCGGCGGAAAAAATATCGCTCCTAT
AGGGCCGATGGTGGCCGGGCATCCGATAATCTATTGGCTCGTAATTTTACATCCGAAATCAGTGGATTGAAGTGGTGTAC
AGATGTCACAGAGTTCCGAGTTGGAGCACAGAAGCTGTATTTGTCGGTGATACAAGACCTGTTTAATAATGAGATTATTT
CTTGGCATATGTCAGAAAGAGCAGCATTAATCCTGACGTGCAAGACGCTGGAAAAAGCGCTGAAAGTGAAAGGGAGAAAA
GAAGGCCTGATGTTGCACAGCGATCAGGGCTGGCATTACCGAACGCCGATGTGGCGCTCAATGCTTGTCGAGGCGGGGAT
ATGTAACGAACGGTGCAATAGTGATCCACACCCAACGCCTGAAATCAGATCCAGGGGGTAA

Upstream 100 bases:

>100_bases
TGAGAGAAGAAAAGGCACTCAGGGAGCAGCAGAAAAAACCAGAATAGTTCAAGCACTGACAGCAGAACATCGACTTTCTT
GCCTACTGTGTGCCGCAAAA

Downstream 100 bases:

>100_bases
TCTGCTCTCCTGATTCAGGAGAGTTTATGGTCACTTTTGAGACAGTTATGGAAATTAAAATCCTGCACAAGCAGGGAATG
AGTAGCCGGGCGATTGCCAG

Product: transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVRKLMNQHGLLSLIRRKKYRSY
RADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLYLSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRK
EGLMLHSDQGWHYRTPMWRSMLVEAGICNERCNSDPHPTPEIRSRG

Sequences:

>Translated_206_residues
MARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVRKLMNQHGLLSLIRRKKYRSY
RADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLYLSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRK
EGLMLHSDQGWHYRTPMWRSMLVEAGICNERCNSDPHPTPEIRSRG
>Mature_205_residues
ARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVRKLMNQHGLLSLIRRKKYRSYR
ADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLYLSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRKE
GLMLHSDQGWHYRTPMWRSMLVEAGICNERCNSDPHPTPEIRSRG

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=183, Percent_Identity=28.9617486338798, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1789981, Length=190, Percent_Identity=45.2631578947368, Blast_Score=164, Evalue=4e-42,
Organism=Escherichia coli, GI1788405, Length=151, Percent_Identity=36.4238410596026, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787263, Length=151, Percent_Identity=36.4238410596026, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1786753, Length=151, Percent_Identity=36.4238410596026, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1786570, Length=151, Percent_Identity=36.4238410596026, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1786490, Length=151, Percent_Identity=36.4238410596026, Blast_Score=94, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 23765; Mature: 23633

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVR
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHH
KLMNQHGLLSLIRRKKYRSYRADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRKEGLMLHSDQGWHYRTPMWRS
HHHHHHHHCCCEEEEECCCCEEEEEEHHHHHHHHHHCCCCCCEEEECCCCCEECCHHHHH
MLVEAGICNERCNSDPHPTPEIRSRG
HHHHHCCCHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVR
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHH
KLMNQHGLLSLIRRKKYRSYRADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRKEGLMLHSDQGWHYRTPMWRS
HHHHHHHHCCCEEEEECCCCEEEEEEHHHHHHHHHHCCCCCCEEEECCCCCEECCHHHHH
MLVEAGICNERCNSDPHPTPEIRSRG
HHHHHCCCHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]