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The map label for this gene is trpD [H]

Identifier: 221232559

GI number: 221232559

Start: 1780885

End: 1781889

Strand: Reverse

Name: trpD [H]

Synonym: SPN23F_18350

Alternate gene names: 221232559

Gene position: 1781889-1780885 (Counterclockwise)

Preceding gene: 221232560

Following gene: 221232558

Centisome position: 80.22

GC content: 43.68

Gene sequence:

>1005_bases
ATGAAAGAGATTATTGAAAAACTAGCAAAATTTGAAAATTTATCAGGTGTGGAAATGACGGATGTCATTGAGCGTATCGT
AACTGGGCGTGTAACTGAAGCGCAGATTGCTTCTCTCCTCTTAGCTCTTAAGATGAAGGGGGAAACACCTGAAGAACGTA
CAGCCATTGCCCAAGTCATGAGAGGACATGCCCAGCATATTCCAACTGAGATTCATGATGCTATGGACAACTGTGGTACA
GGTGGGGACAAGTCTTTCAGTTTTAATATTTCCACAACTGCAGCCTTTGTCTTGGCTGGTGGCGGTATTCACATGGCCAA
GCATGGTAACCGCTCGATTTCTTCTAAATCTGGTTCCGCAGATGTCCTCGAAGCCTTGGGAATCAATCTTGACCTCAAAC
CAGCTGAACTAGGTAAGGTCTTTGATAAAACTGGAATCGTCTTTCTCTTCGCTAAAAATATGCACCCAGCTATGAAATAC
ATCATGCCAGCTCGTTTGGAATTGGGAATTCCAACGATTATGAACTTGACTGGTCCACTGATTCATCCAATGGCTTTAGA
AACACAGCTTCTTGGAATTAGTCGTCCAGAACTCCTAGAAAGTACAGCTCAGGTTTTGAAAAATATGGGTCGCAAACGTG
CCATCGTGGTTGCTGGACCAGAAGGGTTGGATGAAGCTGGCTTGAACGGAACAACCAAGATTGCACTTCTTGAAAATGGC
GAAATCAGCTTGTCAAGCTTTACTCCAGAGGATTTGGGAATGGAAGACTATGCTATGGAAGATATTCGTGGTGGGAATGC
TCAGGAAAATGCAGAAATTTTGCTTAGCGTTCTGAAAAACGAAGCAAGTCCATTCTTGGAAACGACAGTCTTGAATGCTG
GTCTTGGTTTCTATGCTAATGGTAAGATTGATAGCATCAAGGAAGGAGTTGCCTTGGCCCGTCAAGTGATTGCTAGAGGC
AAGGCCCTTGAAAAACTCAGACTGTTACAGGAGTACCAAAAATGA

Upstream 100 bases:

>100_bases
ATTTATGGCTTCCAGTACCATCCAGAGAGCATTGGAACGCCAGACGGCTTGTCTTCTATTCGGAATTTTATCGAGAAGGT
TGTAAAGTGAGGAAACTAGG

Downstream 100 bases:

>100_bases
GTCAGGAATTTTTAGCACGAATCTTAGAGCAGAAGGCGCGTGAGGTGGAGCAGATGAAGCTGGAGCAAATCCAGCCTCTG
CGCCAGACCTATCGCTTGGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALKMKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGT
GGDKSFSFNISTTAAFVLAGGGIHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVAGPEGLDEAGLNGTTKIALLENG
EISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLSVLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARG
KALEKLRLLQEYQK

Sequences:

>Translated_334_residues
MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALKMKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGT
GGDKSFSFNISTTAAFVLAGGGIHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVAGPEGLDEAGLNGTTKIALLENG
EISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLSVLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARG
KALEKLRLLQEYQK
>Mature_334_residues
MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALKMKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGT
GGDKSFSFNISTTAAFVLAGGGIHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVAGPEGLDEAGLNGTTKIALLENG
EISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLSVLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARG
KALEKLRLLQEYQK

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=279, Percent_Identity=39.7849462365591, Blast_Score=186, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6320561, Length=268, Percent_Identity=30.2238805970149, Blast_Score=111, Evalue=2e-25,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 35963; Mature: 35963

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALKMKGETPEERTAIAQVM
CHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGGIHMAKHGNRSISSKSGSA
HHHHHHCCHHHHHHHHHCCCCCCCEEEEEEHHHEEEEEECCCEEEECCCCCCCCCCCCCH
DVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKYIMPARLELGIPTIMNLTGPL
HHHHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHCCCCH
IHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVAGPEGLDEAGLNGTTKIALLENG
HCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEEECC
EISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLSVLKNEASPFLETTVLNAGLGFYAN
CEEECCCCCHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEC
GKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALKMKGETPEERTAIAQVM
CHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGGIHMAKHGNRSISSKSGSA
HHHHHHCCHHHHHHHHHCCCCCCCEEEEEEHHHEEEEEECCCEEEECCCCCCCCCCCCCH
DVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKYIMPARLELGIPTIMNLTGPL
HHHHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHCCCCH
IHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVAGPEGLDEAGLNGTTKIALLENG
HCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEEECC
EISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLSVLKNEASPFLETTVLNAGLGFYAN
CEEECCCCCHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEC
GKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA