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The map label for this gene is trpB [H]

Identifier: 221232556

GI number: 221232556

Start: 1778334

End: 1779557

Strand: Reverse

Name: trpB [H]

Synonym: SPN23F_18320

Alternate gene names: 221232556

Gene position: 1779557-1778334 (Counterclockwise)

Preceding gene: 221232557

Following gene: 221232555

Centisome position: 80.11

GC content: 48.61

Gene sequence:

>1224_bases
ATGGCATATCAGGAACCAAATAAAGATGGATTTTACGGAAAATTCGGCGGACGTTTTGTCCCAGAAACATTGATGACAGC
AGTTTTGGAGTTGGAGAAGGCCTATCGTGAAAGTCAGGCAGACCCAAGTTTCCAAGAGGAATTAAACCAACTCTTGCGCC
AGTATGTGGGGCGGGAAACTCCTCTTTACTACGCAAAAAACTTGACCCAGCATATTGGCGGAGCCAAGATTTATCTCAAA
CGGGAAGACCTTAACCATACAGGAGCCCACAAGATTAACAATGCCTTAGGACAAGTTTGGCTTGCCAAACGCATGGGTAA
AAAGAAAATTATCGCAGAAACCGGTGCTGGTCAGCACGGTGTGGCAACTGCAACTGCTGCGGCCCTCTTTAACATGGAAT
GTACCATCTACATGGGTGAGGAAGATGTCAAACGCCAAGCCCTCAATGTCTTCCGCATGGAGCTTTTGGGAGCCAAGGTC
GAGGCTGTAACAGATGGTTCGCGCGTGCTCAAGGATGCGGTCAATGCAGCCCTTCGTTCATGGGTGGCTAATATCGACGA
TACCCACTATATCCTTGGTTCTGCCTTGGGGCCTCATCCATTTCCAGAAATCGTTCGTGACTTCCAAAGTGTCATCGGTC
GCGAAGCTAAACAACAGTATCGCGATATGACAGGTCAAAATCTGCCCGATGCTCTAGTAGCCTGTGTTGGTGGTGGATCT
AATGCTATTGGGCTCTTCCATCCCTTTGTAGAAGATGAGTCAGTAGCTATGTATGGAACTGAAGCAGCAGGGCTTGGTGT
GGATACAGAGCACCACGCTGCTACCTTGACCAAGGGTCGTCCGGGTGTTCTTCACGGTTCTCTCATGGATGTGCTCCAAG
ATGCCCATGGTCAAATTCTTGAAGCCTTCTCTATCTCAGCAGGTTTGGACTATCCTGGTATTGGTCCAGAACATTCTCAC
TACCACGATATCAAACGTGCCAGCTATGTCCCTGTGACAGACGAAGAAGCCTTGGAAGGATTCCAACTCTTGTCTCGTGT
GGAAGGGATTATCCCAGCCTTGGAATCTAGCCATGCTATCGCTTTTGCGGTGAAATTGGCCAAAGAACTTGGACCAGAAA
AGTCTATGATTGTCTGCCTATCAGGTCGTGGGGACAAGGATGTGGTTCAAGTCAAAGACCGCTTGGAAGCAGATGCAGCA
AAGAAGGGAGAAGCTCATGCCTAA

Upstream 100 bases:

>100_bases
CAACATTTTACTCCCTATGCAGTAGATGTATCGAGCGGAGTGGAGACAGATGGACAAAAAAATCATGAAAAGATTAGAAG
ATTTATAGAGAGGGTAAAGC

Downstream 100 bases:

>100_bases
GACACTAACAGAAAAATTGAATGCTATTAAAGCAGCTGGAAAAGGAATTTTTGTTCCCTATATCATGGCTGGTGACCACG
AGAAAGGTTTGGACGGTCTT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSFQEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLK
REDLNHTGAHKINNALGQVWLAKRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQQYRDMTGQNLPDALVACVGGGS
NAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATLTKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSH
YHDIKRASYVPVTDEEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVKDRLEADAA
KKGEAHA

Sequences:

>Translated_407_residues
MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSFQEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLK
REDLNHTGAHKINNALGQVWLAKRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQQYRDMTGQNLPDALVACVGGGS
NAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATLTKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSH
YHDIKRASYVPVTDEEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVKDRLEADAA
KKGEAHA
>Mature_406_residues
AYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSFQEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKR
EDLNHTGAHKINNALGQVWLAKRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKVE
AVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQQYRDMTGQNLPDALVACVGGGSN
AIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATLTKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHY
HDIKRASYVPVTDEEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVKDRLEADAAK
KGEAHA

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=389, Percent_Identity=53.2133676092545, Blast_Score=414, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6321412, Length=392, Percent_Identity=57.9081632653061, Blast_Score=478, Evalue=1e-136,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 44265; Mature: 44134

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSFQEELNQLLRQYVGRET
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
PLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLAKRMGKKKIIAETGAGQHG
CHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCC
VATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKVEAVTDGSRVLKDAVNAALRS
HHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHH
WVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQQYRDMTGQNLPDALVACVGGGS
HHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCC
NAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATLTKGRPGVLHGSLMDVLQDAHGQIL
CCEEHCCCCCCCCCEEEECCCCCCCCCCCCHHHHEECCCCCCCCHHHHHHHHHHHHHHHH
EAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTDEEALEGFQLLSRVEGIIPALESSHAI
HHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
AFAVKLAKELGPEKSMIVCLSGRGDKDVVQVKDRLEADAAKKGEAHA
HHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSFQEELNQLLRQYVGRET
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
PLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLAKRMGKKKIIAETGAGQHG
CHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCC
VATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKVEAVTDGSRVLKDAVNAALRS
HHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHH
WVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQQYRDMTGQNLPDALVACVGGGS
HHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCC
NAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATLTKGRPGVLHGSLMDVLQDAHGQIL
CCEEHCCCCCCCCCEEEECCCCCCCCCCCCHHHHEECCCCCCCCHHHHHHHHHHHHHHHH
EAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTDEEALEGFQLLSRVEGIIPALESSHAI
HHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
AFAVKLAKELGPEKSMIVCLSGRGDKDVVQVKDRLEADAAKKGEAHA
HHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA