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The map label for this gene is licC [H]

Identifier: 221232549

GI number: 221232549

Start: 1771182

End: 1772444

Strand: Reverse

Name: licC [H]

Synonym: SPN23F_18250

Alternate gene names: 221232549

Gene position: 1772444-1771182 (Counterclockwise)

Preceding gene: 221232551

Following gene: 221232548

Centisome position: 79.79

GC content: 34.76

Gene sequence:

>1263_bases
ATGGAAAAATTATTACAAGAAAAGTTACTTCCAGTAGCGGCTAGATTGGGTAATAATAAAGCGTTGGTTTCTATTCGAGA
CGGTATTACTCTAACTATACCTTTATTGTTGATAGGTTCATTACTAATGGTTATTGCAAGTTTTCCTATTCCAGGATGGG
AACAATATCTGGGTGATATTGGTGTTGCTGACTATTTATGGAAGGGTGTTGATAGTAGTTTTGGATTACTTGGTCTTGTA
GCTAGTTTTGGTATCGCTTACTTTATGGCTAGACAATACAAAGTTGATGGTATTCCTGCTGGTATTGTGTCATTATCATC
TTTTATTACAGTTACGCCTTTCATTAGAGGAGAGGCTGGAGCAGGAATGCCTACCGCTTTCATGGCATCAAAAGGTTTAT
TTGTTGCTATGATTTTAGGATTGATTAATGGCTATATCTACCAATGGTTTATAAATCATAATATACAGATAAAAATGCCG
GATGGTGTTCCACCAGCAGTATCTAAAAGCTTTAGTGCCATTATTCCTGGTGCAGTGACTATTGTTGGTTGGTTGATTGT
TTATGCAACTTTAGATAAATTAAGTTTACCTAATCTTCATGAAATTGCTCAAGTAGCTTTGGGAGGTCCACTTGGACTTT
TAGGAAATAATGTTATTGGTCTTCTTATCTTAATTTTCCTTAATAGTAGTTTTTGGTTTGTAGGATTACACGGAGGAAAT
GTTGTTAATGCAGTTATGAAACCGTTATGGTTAGCTAATCTAGATGCAAATAAAGTAGCTTATCAAACTGGAGAAACTCT
TCCAAATATTTTTACTAGCGTATTTATGGATAATTTTGTATTCATAGGTGGCGGTGGTGCAACCATAGGTTTAGTTCTTG
CGTTAGGATATTTAGCACATAAGAAGAAAGCTAGTAAACAACTAAAAACTTTGGCACCTATAACTGTTATACCTGGATTA
TTTAATATAAATGAACCAGCAATGTTTGGCGTTCCTATTGTTTTGAACATTTTGTTACTAGTTCCATTTATCTTAGCTCC
AATGTTTAACTTACTAGTAGCGTGGGGAGCAATGGCATCAGGTTTGGTTCCGCTAACTTATACAGATCCAGGTTGGACTA
TGCCACCTGTTATAAGTGGTTTACTTGCTACAGGAAGTATTTCTGGTTCATTATTACAAATTGTATTGATTGTTTTGGAT
GTCTTACTTTATTTACCATTTGTAATAGCTATTGAAAAACGGTTTAAGTTATTGGAGGATTGA

Upstream 100 bases:

>100_bases
AAATATAAATAACAAAAGATAATCAAATAACAACTTGACGTCAAAAAATAAAGATAATTGATAACTTTTGATAATAAAAT
ATATTTAAGAGGAAAAGGTT

Downstream 100 bases:

>100_bases
GAATGAAACGTTTAATTAGTGCAAATCCATCTGAGATATTACAGATGAATGCTGAAGAATTAAAACAAAGTATTTTAGCA
AGTGAAGGTAGAGTTGTTCT

Product: sugar phosphotransferase system (PTS), IIC component

Products: protein histidine; sugar phosphate

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMVIASFPIPGWEQYLGDIGVADYLWKGVDSSFGLLGLV
ASFGIAYFMARQYKVDGIPAGIVSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNVIGLLILIFLNSSFWFVGLHGGN
VVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFMDNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGL
FNINEPAMFGVPIVLNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLLQIVLIVLD
VLLYLPFVIAIEKRFKLLED

Sequences:

>Translated_420_residues
MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMVIASFPIPGWEQYLGDIGVADYLWKGVDSSFGLLGLV
ASFGIAYFMARQYKVDGIPAGIVSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNVIGLLILIFLNSSFWFVGLHGGN
VVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFMDNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGL
FNINEPAMFGVPIVLNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLLQIVLIVLD
VLLYLPFVIAIEKRFKLLED
>Mature_420_residues
MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMVIASFPIPGWEQYLGDIGVADYLWKGVDSSFGLLGLV
ASFGIAYFMARQYKVDGIPAGIVSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNVIGLLILIFLNSSFWFVGLHGGN
VVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFMDNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGL
FNINEPAMFGVPIVLNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLLQIVLIVLD
VLLYLPFVIAIEKRFKLLED

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=434, Percent_Identity=31.3364055299539, Blast_Score=179, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: 2.7.1.69

Molecular weight: Translated: 44887; Mature: 44887

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMVIASFPIPGWEQYLGDI
CHHHHHHHHHHHHHHCCCCCEEEEEECCCEEHHHHHHHHHHHHHHHHCCCCCHHHHHHCC
GVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGIVSLSSFITVTPFIRGEAG
CHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEECCEEECCCC
AGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMPDGVPPAVSKSFSAIIPGAVT
CCCCHHHHHCCCHHHHHHHHHHHHHHEEEEECCEEEEECCCCCCHHHHCCHHHHCCHHHH
IVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNVIGLLILIFLNSSFWFVGLHGGN
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCH
VVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFMDNFVFIGGGGATIGLVLALGYLAH
HHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHH
KKKASKQLKTLAPITVIPGLFNINEPAMFGVPIVLNILLLVPFILAPMFNLLVAWGAMAS
HHHHHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLVPLTYTDPGWTMPPVISGLLATGSISGSLLQIVLIVLDVLLYLPFVIAIEKRFKLLED
CCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMVIASFPIPGWEQYLGDI
CHHHHHHHHHHHHHHCCCCCEEEEEECCCEEHHHHHHHHHHHHHHHHCCCCCHHHHHHCC
GVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGIVSLSSFITVTPFIRGEAG
CHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEECCEEECCCC
AGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMPDGVPPAVSKSFSAIIPGAVT
CCCCHHHHHCCCHHHHHHHHHHHHHHEEEEECCEEEEECCCCCCHHHHCCHHHHCCHHHH
IVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNVIGLLILIFLNSSFWFVGLHGGN
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCH
VVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFMDNFVFIGGGGATIGLVLALGYLAH
HHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHH
KKKASKQLKTLAPITVIPGLFNINEPAMFGVPIVLNILLLVPFILAPMFNLLVAWGAMAS
HHHHHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLVPLTYTDPGWTMPPVISGLLATGSISGSLLQIVLIVLDVLLYLPFVIAIEKRFKLLED
CCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]