| Definition | Streptococcus pneumoniae ATCC 700669, complete genome. |
|---|---|
| Accession | NC_011900 |
| Length | 2,221,315 |
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The map label for this gene is secA2 [H]
Identifier: 221232496
GI number: 221232496
Start: 1701945
End: 1704317
Strand: Reverse
Name: secA2 [H]
Synonym: SPN23F_17680
Alternate gene names: 221232496
Gene position: 1704317-1701945 (Counterclockwise)
Preceding gene: 221232497
Following gene: 221232495
Centisome position: 76.73
GC content: 41.05
Gene sequence:
>2373_bases GTGTTTAGACGTTTAGGTCAAGATTTCCAGCTTAGGAAAGTGAAAAAGATTTTAAAGCAGATTAATGCCCTGAAAGGCAA GATGTCCTCTCTTTCGGATCAAGAATTAGTAGCTAAAACAGTAGAGTTTCGTCAGCGTCTTTCCGAGGGAGAAAGTCTAG ACGATATTTTGGTTGAAGCTTTTGCTGTGGTGCGTGAAGCAGATAAGCGGATTTTAGGGATGTTTCCTTATGATGTTCAA GTCATGGGAGCTATTGTCATGCACTATGGAAATGTTGCTGAGATGAATACGGGGGAAGGTAAGACCTTGACAGCTACCAT GCCTGTCTATTTGAACGCTTTTTCAGGAGAAGGAGTGATGGTTGTGACTCCTAATGAGTATTTATCAAAGCGTGATGCCG AGGAAATGGGCCAAGTTTATCGTTTTCTAGGATTGACCATTGGTGTACCATTTACGGAAGATCCAAAGAAGGAGATGAAA GCTGAAGAAAAGAAGCTTATCTATGCTTCGGATATCATCTACACAACCAATAGTAATTTAGGTTTTGATTATCTAAATGA TAACCTAGCCTCGAATGAAGAAGGTAAGTTTTTACGACCGTTTAACTATGTGATTATTGATGAAATTGATGATATCTTGC TTGATAGTGCACAAACTCCTCTGATTATTGCGGGTTCTCCTCGTGTTCAGTCTAATTACTATGCGATCATTGATACACTT GTAACAACCTTGGTCGAAGGAGAGGATTATATCTTTAAAGAGGAGAAAGAGGAGGTTTGGCTCACTACTAAGGGGGCCAA GTCTGCTGAGAATTTCCTAGGGATTGATAATTTATACAAGGAAGAGCATGCGTCTTTTGCTCGTCATTTGGTTTATGCGA TTCGAGCTCATAAGCTCTTTACTAAAGATAAGGACTATATCATTCGTGGAAATGAGATGGTACTGGTTGATAAGGGAACA GGGCGTCTAATGGAAATGACTAAACTTCAAGGAGGTCTCCATCAGGCTATTGAAGCCAAGGAACATGTCAAATTATCTCC TGAGACGCGGGCTATGGCCTCGATCACCTATCAGAGTCTTTTTAAGATGTTTAATAAGATATCTGGTATGACAGGGACAG GTAAGGTCGCGGAAAAAGAGTTTATTGAAACTTACAATATGTCTGTAGTACGCATTCCAACCAATCGTCCGAGACAACGG ATTGACTATCCAGATAATCTATATATCACTTTACCTGAAAAAGTGTATGCATCCTTGGAGTACATCAAGCAATACCATGC TAAGGGAAATCCTTTACTCGTTTTTGTAGGCTCAGTTGAAATGTCTCAACTCTATTCGTCTCTCTTGTTTCGTGAAGGGA TTGCCCATAATGTCCTAAATGCTAATAATGCGGCGCGTGAGGCTCAGATTATCTCCGAGTCAGGTCAGATGGGGGCTGTG ACAGTGGCTACCTCTATGGCAGGACGTGGTACGGATATCAAGCTTGGTAAAGGAGTCGCAGAGCTTGGGGGCTTGATTGT TATTGGGACTGAGCGGATGGAAAGTCAGCGGATCGACCTACAAATTCGTGGCCGTTCTGGTCGTCAGGGAGATCCTGGTA TGAGTAAATTTTTTGTATCCTTAGAGGATGATGTTATCAAGAAATTTGGTCCATCTTGGGTGCATAAAAAGTACAAAGAC TATCAGGTTCAAGATATGACTCAACCGGAAGTATTGAAAGGTCGTAAATACCGGAAACTAGTCGAAAAGGCTCAGCATGC CAGTGATAGTGCTGGACGTTCAGCACGTCGTCAGACTCTGGAGTATGCTGAAAGTATGAATATACAACGGGATATAGTCT ATAAAGAGAGAAATCGTCTAATAGATGGTTCTCGTGACTTAGAGGATGTTGTTGTGGATATCATTGAGAGATATACAGAA GAGGTAGCGGCTGATCACTATGCTAGTCGTGAATTATTGTTTCACTTTATTGTGACCAATATTAGTTTTCATGTTAAAGA GGTTCCAGATTATATAGATGTAACTGACAAAACTGCAGTTCGTAGCTTTATGAAGCAGGTGATTGATAAAGAACTTTCTG AAAAGAAAGAATTACTTAATCAACATGACTTATATGAACAGTTTTTACGACTTTCACTGCTTAAAGCCATTGATGACAAC TGGGTAGAGCAGGTAGACTATCTACAACAGCTATCCATGGCTATCGGTGGTCAATCTGCTAGTCAGAAAAATCCAATCGT AGAGTACTATCAAGAAGCCTACGCGGGCTTTGAAGCTATGAAAGAACAAATCCGTGCGGATATGGTGCGTAATCTCCTGA TGGGGCTGGTTGAGGTCACTCCAAAAGGTGAAATCGTGACTCATTTTCCATAA
Upstream 100 bases:
>100_bases TTTACTTATCCAGAAGATAGTTATACTTATCAAGTTTCTCTTTTAAGTGCTGGATTTGAGTCCTTAACTTTTTATCATTT TTCTATCAAGGAGATCAGAA
Downstream 100 bases:
>100_bases GAGGAGAAAATATGACAATTTACAATATAAATTTAGGAATTGGTTGGGCTAGTAGCGGTGTTGAATACGCTCAAGCCTAT CGTGCTGGTGTTTTTCGGAA
Product: preprotein translocase subunit SecA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 790; Mature: 790
Protein sequence:
>790_residues MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFRQRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQ VMGAIVMHYGNVAEMNTGEGKTLTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK AEEKKLIYASDIIYTTNSNLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQTPLIIAGSPRVQSNYYAIIDTL VTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGIDNLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGT GRLMEMTKLQGGLHQAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRIPTNRPRQR IDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLFREGIAHNVLNANNAAREAQIISESGQMGAV TVATSMAGRGTDIKLGKGVAELGGLIVIGTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKD YQVQDMTQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGSRDLEDVVVDIIERYTE EVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRSFMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDN WVEQVDYLQQLSMAIGGQSASQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP
Sequences:
>Translated_790_residues MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFRQRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQ VMGAIVMHYGNVAEMNTGEGKTLTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK AEEKKLIYASDIIYTTNSNLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQTPLIIAGSPRVQSNYYAIIDTL VTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGIDNLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGT GRLMEMTKLQGGLHQAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRIPTNRPRQR IDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLFREGIAHNVLNANNAAREAQIISESGQMGAV TVATSMAGRGTDIKLGKGVAELGGLIVIGTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKD YQVQDMTQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGSRDLEDVVVDIIERYTE EVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRSFMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDN WVEQVDYLQQLSMAIGGQSASQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP >Mature_790_residues MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFRQRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQ VMGAIVMHYGNVAEMNTGEGKTLTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK AEEKKLIYASDIIYTTNSNLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQTPLIIAGSPRVQSNYYAIIDTL VTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGIDNLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGT GRLMEMTKLQGGLHQAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRIPTNRPRQR IDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLFREGIAHNVLNANNAAREAQIISESGQMGAV TVATSMAGRGTDIKLGKGVAELGGLIVIGTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKD YQVQDMTQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGSRDLEDVVVDIIERYTE EVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRSFMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDN WVEQVDYLQQLSMAIGGQSASQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP
Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo
COG id: COG0653
COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the secA family [H]
Homologues:
Organism=Escherichia coli, GI1786287, Length=823, Percent_Identity=38.2746051032807, Blast_Score=531, Evalue=1e-152,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000185 - InterPro: IPR022490 - InterPro: IPR011115 - InterPro: IPR014018 - InterPro: IPR011130 - InterPro: IPR011116 [H]
Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]
EC number: NA
Molecular weight: Translated: 89761; Mature: 89761
Theoretical pI: Translated: 5.96; Mature: 5.96
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.7 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 3.7 %Met (Mature Protein) 3.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFRQRLSEGESLDDILVEA CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH FAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKTLTATMPVYLNAFSGEGVM HHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEEEEEECCCEEE VVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMKAEEKKLIYASDIIYTTNSNL EECCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCEEEEEEEEEECCCCC GFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQTPLIIAGSPRVQSNYYAIIDTL CCHHHCCCCCCCCCCCEECCCCEEECCCHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHH VTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGIDNLYKEEHASFARHLVYAIRAHKLF HHHHHCCCCCEEECCCCCEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH TKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLHQAIEAKEHVKLSPETRAMASITYQSL CCCCCEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH FKMFNKISGMTGTGKVAEKEFIETYNMSVVRIPTNRPRQRIDYPDNLYITLPEKVYASLE HHHHHHHCCCCCCCCHHHHHHHHHHCCEEEECCCCCCHHHCCCCCCEEEEECHHHHHHHH YIKQYHAKGNPLLVFVGSVEMSQLYSSLLFREGIAHNVLNANNAAREAQIISESGQMGAV HHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEE TVATSMAGRGTDIKLGKGVAELGGLIVIGTERMESQRIDLQIRGRSGRQGDPGMSKFFVS EEEEHHCCCCCCEECCCCHHHHCCEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHEEEE LEDDVIKKFGPSWVHKKYKDYQVQDMTQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTL HHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHH EYAESMNIQRDIVYKERNRLIDGSRDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTN HHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH ISFHVKEVPDYIDVTDKTAVRSFMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDN HHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH WVEQVDYLQQLSMAIGGQSASQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVT HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC PKGEIVTHFP CCCCEEECCC >Mature Secondary Structure MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFRQRLSEGESLDDILVEA CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH FAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKTLTATMPVYLNAFSGEGVM HHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEEEEEECCCEEE VVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMKAEEKKLIYASDIIYTTNSNL EECCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCEEEEEEEEEECCCCC GFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQTPLIIAGSPRVQSNYYAIIDTL CCHHHCCCCCCCCCCCEECCCCEEECCCHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHH VTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGIDNLYKEEHASFARHLVYAIRAHKLF HHHHHCCCCCEEECCCCCEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH TKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLHQAIEAKEHVKLSPETRAMASITYQSL CCCCCEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH FKMFNKISGMTGTGKVAEKEFIETYNMSVVRIPTNRPRQRIDYPDNLYITLPEKVYASLE HHHHHHHCCCCCCCCHHHHHHHHHHCCEEEECCCCCCHHHCCCCCCEEEEECHHHHHHHH YIKQYHAKGNPLLVFVGSVEMSQLYSSLLFREGIAHNVLNANNAAREAQIISESGQMGAV HHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEE TVATSMAGRGTDIKLGKGVAELGGLIVIGTERMESQRIDLQIRGRSGRQGDPGMSKFFVS EEEEHHCCCCCCEECCCCHHHHCCEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHEEEE LEDDVIKKFGPSWVHKKYKDYQVQDMTQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTL HHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHH EYAESMNIQRDIVYKERNRLIDGSRDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTN HHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH ISFHVKEVPDYIDVTDKTAVRSFMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDN HHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH WVEQVDYLQQLSMAIGGQSASQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVT HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC PKGEIVTHFP CCCCEEECCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11463916 [H]