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The map label for this gene is murC [H]

Identifier: 221232233

GI number: 221232233

Start: 1436367

End: 1437701

Strand: Reverse

Name: murC [H]

Synonym: SPN23F_14850

Alternate gene names: 221232233

Gene position: 1437701-1436367 (Counterclockwise)

Preceding gene: 221232234

Following gene: 221232232

Centisome position: 64.72

GC content: 41.65

Gene sequence:

>1335_bases
ATGTCAAAGACATATCATTTTATCGGAATTAAGGGATCAGGGATGAGTGCCTTGGCCTTGATGTTGTACCAGATGGGGCA
CAAGGTTCAGGGATCAGATGTTGAAAAGTACTACTTTACCCAACGCGGTCTTGAGCAGGCAGGAATTACCATTCTTCCTT
TTGATGAAAAGAATCTAGACGGTGATATGGAAATTATCGCTGGAAATGCCTTTCGTCCAGATAACAACGTCGAAATTGTC
TATGCGGACCAAAATGGTATCAGCTACAAACGTTACCATGAGTTTCTAGGTAGCTTTATGCGTGACTTTGTTAGCATGGG
AGTAGCAGGAGCACATGGAAAAACTTCAACGACAGGTATGTTGTCTCATGTCTTGTCTCACATTACAGATACCAGCTTCT
TGATTGGAGATGGGACAGGTCGTGGTTCGGCCAATGCCAAATATTTTGTCTTTGAATCTGACGAATATGAGCGTCACTTC
ATGCCTTACCACCCAGAATACTCTATTATCACCAACATTGACTTTGACCATCCAGATTATTTCACAAGTCTCGAGGATGT
TTTCAATGCCTTTAACGACTATGCCAAACAAATCACCAAGGGTCTTTTTGTCTATGGTGAAGATGCTGAATTGCGTAAGA
TTACGTCTGATGCACCAATTTATTATTATGGTTTTGAAGCTGAAGGCAATGACTTTGTAGCTAGTGATCTTCTTCGTTCA
ACAACTGGTTCAACCTTCACCGTTCATTTCCGTGGACAAAACTTGGGGCAATTCCACATTCCAACCTTTGGTCGTCACAA
TATCATGAATGCGACAGCCGTTATTGGTCTTCTTTACACAGCAGGATTTGATTTGAACTTGGTGCGTGAGCACTTGAAAA
CATTTTCCGGTGTTAAACGTCGTTTCACTGAGAAAATTGTCAATGATACAGTGATTATCGATGACTTTGCCCATCATCCA
ACAGAAATTATTGCGACCTTGGATGCGGCTCGTCAGAAATACCCAAGCAAGGAAATTGTAGCAGTCTTTCAACCGCATAC
CTTTACAAGAACCATTGCCTTGTTGGACGACTTTGCCCATGCTTTAAACCAAGCAGATGCTGTTTATCTAGCGCAAATTT
ATGGCTCGGCTCGTGAAGTAGATCATGGTGACGTTAAGGTAGAAGACCTAGCCAACAAAATCAACAAAAAACACCAAGTG
ATTACTGTTGAAAATGTTTCTCCACTCCTAGACCATGACAATGCTGTTTACGTCTTTATGGGAGCAGGAGACATCCAAAC
CTATGAATACTCATTTGAGCGTCTCTTGTCTAACTTGACAAGCAATGTTCAATAG

Upstream 100 bases:

>100_bases
AAGAGCCAAATCTACAATAAAAAAAGTAAACAAACAGAACAAGAACGTCGGGTTGCCCAAGAGTTGAATCTGACCAGAAT
GACAGAATAGGGGAGAAAAC

Downstream 100 bases:

>100_bases
GATGTTCCCATGGAAATTCCAATTAAGATCATTCAGGCAAGCAAGTCTGATTTGCCTGAGATAGGGGCACTTCAGACCTC
GTCTTTTCCAGCTGAAAAGC

Product: UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MSKTYHFIGIKGSGMSALALMLYQMGHKVQGSDVEKYYFTQRGLEQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIV
YADQNGISYKRYHEFLGSFMRDFVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDAPIYYYGFEAEGNDFVASDLLRS
TTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIGLLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHP
TEIIATLDAARQKYPSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLANKINKKHQV
ITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ

Sequences:

>Translated_444_residues
MSKTYHFIGIKGSGMSALALMLYQMGHKVQGSDVEKYYFTQRGLEQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIV
YADQNGISYKRYHEFLGSFMRDFVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDAPIYYYGFEAEGNDFVASDLLRS
TTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIGLLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHP
TEIIATLDAARQKYPSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLANKINKKHQV
ITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ
>Mature_443_residues
SKTYHFIGIKGSGMSALALMLYQMGHKVQGSDVEKYYFTQRGLEQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIVY
ADQNGISYKRYHEFLGSFMRDFVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHFM
PYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDAPIYYYGFEAEGNDFVASDLLRST
TGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIGLLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPT
EIIATLDAARQKYPSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLANKINKKHQVI
TVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1790680, Length=389, Percent_Identity=31.1053984575836, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1786279, Length=455, Percent_Identity=29.8901098901099, Blast_Score=136, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 49945; Mature: 49813

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTYHFIGIKGSGMSALALMLYQMGHKVQGSDVEKYYFTQRGLEQAGITILPFDEKNLD
CCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHCCCEEEECCCCCCC
GDMEIIAGNAFRPDNNVEIVYADQNGISYKRYHEFLGSFMRDFVSMGVAGAHGKTSTTGM
CCEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHFMPYHPEYSIITNIDFDHPDY
HHHHHHHHCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCHH
FTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDAPIYYYGFEAEGNDFVASDLLRS
HHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHCCCCCEEEEEEECCCCCHHHHHHHHH
TTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIGLLYTAGFDLNLVREHLKTFSGVKR
CCCCEEEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
RFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKYPSKEIVAVFQPHTFTRTIALLDDFAH
HHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHH
ALNQADAVYLAQIYGSAREVDHGDVKVEDLANKINKKHQVITVENVSPLLDHDNAVYVFM
HHCCCCHHHHHHHHCCCCCCCCCCEEHHHHHHHHCCCEEEEEECCCCHHHCCCCEEEEEE
GAGDIQTYEYSFERLLSNLTSNVQ
ECCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKTYHFIGIKGSGMSALALMLYQMGHKVQGSDVEKYYFTQRGLEQAGITILPFDEKNLD
CCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHCCCEEEECCCCCCC
GDMEIIAGNAFRPDNNVEIVYADQNGISYKRYHEFLGSFMRDFVSMGVAGAHGKTSTTGM
CCEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHFMPYHPEYSIITNIDFDHPDY
HHHHHHHHCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCHH
FTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDAPIYYYGFEAEGNDFVASDLLRS
HHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHCCCCCEEEEEEECCCCCHHHHHHHHH
TTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIGLLYTAGFDLNLVREHLKTFSGVKR
CCCCEEEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
RFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKYPSKEIVAVFQPHTFTRTIALLDDFAH
HHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHH
ALNQADAVYLAQIYGSAREVDHGDVKVEDLANKINKKHQVITVENVSPLLDHDNAVYVFM
HHCCCCHHHHHHHHCCCCCCCCCCEEHHHHHHHHCCCEEEEEECCCCHHHCCCCEEEEEE
GAGDIQTYEYSFERLLSNLTSNVQ
ECCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA