Definition Streptococcus pneumoniae ATCC 700669, complete genome.
Accession NC_011900
Length 2,221,315

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The map label for this gene is atpE

Identifier: 221232226

GI number: 221232226

Start: 1430660

End: 1430860

Strand: Reverse

Name: atpE

Synonym: SPN23F_14780

Alternate gene names: 221232226

Gene position: 1430860-1430660 (Counterclockwise)

Preceding gene: 221232227

Following gene: 221232225

Centisome position: 64.41

GC content: 34.33

Gene sequence:

>201_bases
ATGAATTTAACATTTTTAGGCTTATGTATTGCCTGTATGGGCGTATCTGTCGGTGAAGGTTTATTGATGAATGGACTGTT
TAAATCAGTAGCACGCCAACCAGATATGCTTTCTGAGTTTCGTAGTTTGATGTTTTTAGGTGTTGCCTTTATTGAAGGAA
CTTTCTTTGTAACTCTTGTCTTCTCATTTATTATCAAATAA

Upstream 100 bases:

>100_bases
TAATTTTTATTAAACGCTTCCAATAGCGGTTAAAAGTTGACAAATTTAAATTTTAGGACTACACTAAGTAAGTAAATTTT
ATTTTAAAGGAGAATTTGTT

Downstream 100 bases:

>100_bases
ATACATGGAACGAGAAGAAAAGGGAGGATTTTAGATGGAAGAAAGTATTAATCCAATCATCTCTATTGGTCCTGTTATCT
TCAATCTGACTATGTTAGCC

Product: F0F1 ATP synthase subunit C

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(0) sector subunit c; F-type ATPase subunit c; F-ATPase subunit c; Lipid-binding protein

Number of amino acids: Translated: 66; Mature: 66

Protein sequence:

>66_residues
MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLMFLGVAFIEGTFFVTLVFSFIIK

Sequences:

>Translated_66_residues
MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLMFLGVAFIEGTFFVTLVFSFIIK
>Mature_66_residues
MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLMFLGVAFIEGTFFVTLVFSFIIK

Specific function: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits

COG id: COG0636

COG function: function code C; F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase C chain family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPL_STRP2 (Q04HT3)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816803.1
- ProteinModelPortal:   Q04HT3
- SMR:   Q04HT3
- STRING:   Q04HT3
- EnsemblBacteria:   EBSTRT00000020613
- GeneID:   4441163
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1341
- eggNOG:   COG0636
- GeneTree:   EBGT00050000026934
- HOGENOM:   HBG753983
- OMA:   FITLAMS
- ProtClustDB:   PRK13467
- HAMAP:   MF_01396
- InterPro:   IPR000454
- InterPro:   IPR020537
- InterPro:   IPR002379
- Gene3D:   G3DSA:1.20.20.10
- PRINTS:   PR00124

Pfam domain/function: PF00137 ATP-synt_C; SSF81333 ATPase_F0/V0_c

EC number: 3.6.3.14

Molecular weight: Translated: 7260; Mature: 7260

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00605 ATPASE_C

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12e6e324)-; HASH(0x13871520)-;

Cys/Met content:

3.0 %Cys     (Translated Protein)
7.6 %Met     (Translated Protein)
10.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
7.6 %Met     (Mature Protein)
10.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLMFLGVAFIEGTFFVTLV
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FSFIIK
HHHHHH
>Mature Secondary Structure
MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLMFLGVAFIEGTFFVTLV
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FSFIIK
HHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA