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The map label for this gene is sglT [H]

Identifier: 221232003

GI number: 221232003

Start: 1187751

End: 1189292

Strand: Reverse

Name: sglT [H]

Synonym: SPN23F_12200

Alternate gene names: 221232003

Gene position: 1189292-1187751 (Counterclockwise)

Preceding gene: 221232004

Following gene: 221232002

Centisome position: 53.54

GC content: 36.06

Gene sequence:

>1542_bases
ATGGGCACAACAGGATTTACAATAATTGACTTAATTATCTTGATTGTTTATTTACTTGCGGTGTTGGTTGCAGGTATCTA
TTTCTCTAAAAAAGAGATGAAAGGAAAAGAGTTCTTTAAAGGAGATGGTTCGGTTCCTTGGTATGTTACTTCGGTATCCA
TTTTTGCCACAATGCTCAGTCCGATTTCCTTCTTGGGACTCGCTGGTAACTCTTATGCAGGTAGCTGGATTTTATGGTTT
GCTCAATTAGGGATGGTTGTAGCTATTCCACTGACAATTCGTTTTATCTTACCTATCTTTGCACGGATAGACATCGATAC
GGCATATGATTACTTGGATAAACGTTTTAATTCTAAAGCACTTCGTATTATTTCAGCACTCTTGTTTATTATTTATCAAT
TGGGACGTATGTCTATCATTATGTACCTCCCATCAGCTGGTTTATCAGTATTGACAGGAATTGACATCAATATTTTGATT
ATTTTGATGGGTGCAATTGCAATTGTTTATTCTTATACTGGTGGTCTAAAATCCGTATTATGGACAGACTTTATTCAAGG
TGTGGTTCTGATTAGTGGTGTCGTTGTAGCTTTATTTGTACTGATGGCTAATATTAAAGGTGGCTTTGGTGCAGTAGCAG
AAACATTAGCAAACGGGAAATTCCTTGCTGCAAATGAAAAACTTTTCGATCCTAACTTGCTTTCAAACTCCATCTTCTTA
ATTGTGATGGGTTCAGGCTTTACAATCTTGTCTTCCTATGCTTCATCTCAAGATTTGGTTCAACGTTTTACTACAACACA
AAATATTAAGAAACTTAATAAAATGTTGTTCACAAATGGTGTCTTGTCACTTGCAATTGCAACAGTCTTTTACTTGATCG
GTACAGGCTTGTACGTATTCTATCAAGTACAAAATGCAGGTAGTGCAGCTAGCAATATCCCTCAAGACCAAATCTTTATG
TACTTTATTGCATACCAGTTACCAGTAGGTGTCACAGGTTTGATCTTGGCAGCGATTTATGCAGCAGCTCAATCAACTGT
TTCAACAGGTTTGAACTCTGTTGCAACTTCATGGACATTGGATATTCAAGATGTCATTTCTAAAAATATGTCAGAGGATC
GTCGTACGAAAATTGCACAATTCGTATCTCTAGCAGTAGGTTTATTCTCAATTGTTGTTTCCATTATCATGGCTCATTCA
GATATTAAATCTGCATACGAATGGTTCAATAGTTTCATGGGACTTGTACTTGGTCTACTTGGTGGTGTATTCATTCTTGG
TTTTGTTTCTAAAAAAGCAAATAAACAAGGTGCTTATGCAGCGCTGATTGTATCAACCATCGTTATGGTATTTATTAAAT
ACTTCCTTCCTCCAACAGCTGTTAGCTACTGGGCATATTCATTGATTTCAATTTCTGTATCAGTAGTTTCAGGTTATATT
GTATCTGTTCTTACTGAAAATAAAGTATCTGCACCTAAATATACAACGATTCATGATATTTCAGAAATTAAAGCGGATTC
AAGTTGGGAAGTTCGTCACTAG

Upstream 100 bases:

>100_bases
GGCAGAAGGTGACTTGGAAGTTGCAAAACAAGCAGCAGAACTTATTCAACAAGCACGAAAAGAATTTTTATAATAAATAA
AATCAATATGGAGATATGTT

Downstream 100 bases:

>100_bases
TCACTAATAGAAAAGAGAAAATAATATGATTATTTCTGAACAATCTGATTTTAGACGATATGCTTCTGTCAATAAACATT
TTTCAAAAGTCTGTGATTTT

Product: sodium:solute symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGSVPWYVTSVSIFATMLSPISFLGLAGNSYAGSWILWF
AQLGMVVAIPLTIRFILPIFARIDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
ILMGAIAIVYSYTGGLKSVLWTDFIQGVVLISGVVVALFVLMANIKGGFGAVAETLANGKFLAANEKLFDPNLLSNSIFL
IVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKMLFTNGVLSLAIATVFYLIGTGLYVFYQVQNAGSAASNIPQDQIFM
YFIAYQLPVGVTGLILAAIYAAAQSTVSTGLNSVATSWTLDIQDVISKNMSEDRRTKIAQFVSLAVGLFSIVVSIIMAHS
DIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMVFIKYFLPPTAVSYWAYSLISISVSVVSGYI
VSVLTENKVSAPKYTTIHDISEIKADSSWEVRH

Sequences:

>Translated_513_residues
MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGSVPWYVTSVSIFATMLSPISFLGLAGNSYAGSWILWF
AQLGMVVAIPLTIRFILPIFARIDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
ILMGAIAIVYSYTGGLKSVLWTDFIQGVVLISGVVVALFVLMANIKGGFGAVAETLANGKFLAANEKLFDPNLLSNSIFL
IVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKMLFTNGVLSLAIATVFYLIGTGLYVFYQVQNAGSAASNIPQDQIFM
YFIAYQLPVGVTGLILAAIYAAAQSTVSTGLNSVATSWTLDIQDVISKNMSEDRRTKIAQFVSLAVGLFSIVVSIIMAHS
DIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMVFIKYFLPPTAVSYWAYSLISISVSVVSGYI
VSVLTENKVSAPKYTTIHDISEIKADSSWEVRH
>Mature_512_residues
GTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGSVPWYVTSVSIFATMLSPISFLGLAGNSYAGSWILWFA
QLGMVVAIPLTIRFILPIFARIDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILII
LMGAIAIVYSYTGGLKSVLWTDFIQGVVLISGVVVALFVLMANIKGGFGAVAETLANGKFLAANEKLFDPNLLSNSIFLI
VMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKMLFTNGVLSLAIATVFYLIGTGLYVFYQVQNAGSAASNIPQDQIFMY
FIAYQLPVGVTGLILAAIYAAAQSTVSTGLNSVATSWTLDIQDVISKNMSEDRRTKIAQFVSLAVGLFSIVVSIIMAHSD
IKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMVFIKYFLPPTAVSYWAYSLISISVSVVSGYIV
SVLTENKVSAPKYTTIHDISEIKADSSWEVRH

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI256985183, Length=459, Percent_Identity=27.0152505446623, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI157671931, Length=482, Percent_Identity=26.3485477178423, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI167466278, Length=444, Percent_Identity=26.5765765765766, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI4507035, Length=416, Percent_Identity=28.6057692307692, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI14140236, Length=476, Percent_Identity=23.7394957983193, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI17941285, Length=469, Percent_Identity=23.454157782516, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4507031, Length=460, Percent_Identity=22.8260869565217, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI110835708, Length=472, Percent_Identity=23.3050847457627, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI4507033, Length=466, Percent_Identity=21.8884120171674, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI109659836, Length=478, Percent_Identity=23.4309623430962, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI310128183, Length=519, Percent_Identity=26.2042389210019, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI109659839, Length=493, Percent_Identity=23.1237322515213, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI206597483, Length=377, Percent_Identity=20.9549071618037, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1790113, Length=446, Percent_Identity=25.5605381165919, Blast_Score=85, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI115533094, Length=529, Percent_Identity=21.3610586011342, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32566512, Length=388, Percent_Identity=25, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI115533096, Length=321, Percent_Identity=22.1183800623053, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573698, Length=475, Percent_Identity=26.7368421052632, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24651739, Length=455, Percent_Identity=25.4945054945055, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281362918, Length=455, Percent_Identity=27.2527472527473, Blast_Score=129, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24651741, Length=431, Percent_Identity=25.0580046403712, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI28574994, Length=460, Percent_Identity=25.6521739130435, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI221459588, Length=464, Percent_Identity=23.2758620689655, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI221459586, Length=467, Percent_Identity=24.4111349036403, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI221459584, Length=403, Percent_Identity=25.3101736972705, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24645928, Length=359, Percent_Identity=26.7409470752089, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24650192, Length=398, Percent_Identity=25.3768844221106, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281362054, Length=450, Percent_Identity=25.3333333333333, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI281362052, Length=450, Percent_Identity=25.3333333333333, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI281362050, Length=450, Percent_Identity=25.3333333333333, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24648056, Length=450, Percent_Identity=25.3333333333333, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI21356827, Length=450, Percent_Identity=25.3333333333333, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24640370, Length=476, Percent_Identity=24.5798319327731, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI221459582, Length=363, Percent_Identity=25.6198347107438, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24641117, Length=468, Percent_Identity=26.7094017094017, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI19920916, Length=428, Percent_Identity=24.7663551401869, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI221379702, Length=348, Percent_Identity=25.8620689655172, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281364280, Length=395, Percent_Identity=24.5569620253165, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI161076631, Length=338, Percent_Identity=25.1479289940828, Blast_Score=87, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 55812; Mature: 55680

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGSVPWYVTSVSIFATMLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEHHHHHHHHHHHH
PISFLGLAGNSYAGSWILWFAQLGMVVAIPLTIRFILPIFARIDIDTAYDYLDKRFNSKA
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCHHH
LRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILIILMGAIAIVYSYTGGLKSVL
HHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHH
WTDFIQGVVLISGVVVALFVLMANIKGGFGAVAETLANGKFLAANEKLFDPNLLSNSIFL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCEEE
IVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKMLFTNGVLSLAIATVFYLIGTGLYVF
EEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
YQVQNAGSAASNIPQDQIFMYFIAYQLPVGVTGLILAAIYAAAQSTVSTGLNSVATSWTL
EEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
DIQDVISKNMSEDRRTKIAQFVSLAVGLFSIVVSIIMAHSDIKSAYEWFNSFMGLVLGLL
EHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGVFILGFVSKKANKQGAYAALIVSTIVMVFIKYFLPPTAVSYWAYSLISISVSVVSGYI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
VSVLTENKVSAPKYTTIHDISEIKADSSWEVRH
HHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
GTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGSVPWYVTSVSIFATMLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEHHHHHHHHHHHH
PISFLGLAGNSYAGSWILWFAQLGMVVAIPLTIRFILPIFARIDIDTAYDYLDKRFNSKA
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCHHH
LRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILIILMGAIAIVYSYTGGLKSVL
HHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHH
WTDFIQGVVLISGVVVALFVLMANIKGGFGAVAETLANGKFLAANEKLFDPNLLSNSIFL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCEEE
IVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKMLFTNGVLSLAIATVFYLIGTGLYVF
EEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
YQVQNAGSAASNIPQDQIFMYFIAYQLPVGVTGLILAAIYAAAQSTVSTGLNSVATSWTL
EEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
DIQDVISKNMSEDRRTKIAQFVSLAVGLFSIVVSIIMAHSDIKSAYEWFNSFMGLVLGLL
EHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGVFILGFVSKKANKQGAYAALIVSTIVMVFIKYFLPPTAVSYWAYSLISISVSVVSGYI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
VSVLTENKVSAPKYTTIHDISEIKADSSWEVRH
HHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]