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The map label for this gene is nanB [H]

Identifier: 221232001

GI number: 221232001

Start: 1185043

End: 1187265

Strand: Reverse

Name: nanB [H]

Synonym: SPN23F_12180

Alternate gene names: 221232001

Gene position: 1187265-1185043 (Counterclockwise)

Preceding gene: 221232002

Following gene: 221232000

Centisome position: 53.45

GC content: 35.13

Gene sequence:

>2223_bases
ATGAAAAAAAATATTAAACAATATGTAACCTTAGGTACTGTAGTGGTATTATCAGCATTTGTTGCTAACTCAGTTGCAGC
TCAGGAGACTGAAACTTCTGAAGTATCAACACCAGAGTTGGTGCAACCTGTTGCACCAACGACTTCGATTTCGGAAGTAC
AACATAAATCGGGTAACTCTTCGGAAGTTACTGTACAACCTCGAACAGTTGAAACTACTGTTAAGGATCCATCTTCTACA
GCGGAAGAAACTCCTGTCTTAGAAAAAAATAATGTTACTTTAACAGGGGGCGGAGAAAATGTTACTAATGAGTTAAAGGA
TAAATTTACTAGCGGTGACTTTACTGTAGTGATTAAGTACAATCAGTCTAGTGAGAAAGGTTTACAAGCTCTGTTTGGAA
TATCTAATTCTAAACCCGGTCAACAAAATAGTTATGTAGATGTGTTCCTTAGAGACAATGGTGAATTGGGAATGGAAGCG
CGTGATACTTCTTCCAATAAAAATCACCTAGTAACCAGACCTGCTTCAGTTTGGGGTAAGTACAAACAAGAGGCCGTGAC
GAACACTGTTGCAGTAGTAGCAGATTCAGTCAAAAAAACGTATTCTTTATATGCAAATGGTACAAAAGTAGTAGAAAAGA
AAGTGGATAACTTCCTAAACATCAAGGATATTAAAGGTATTGATTACTATATGCTTGGGGGAGTGAAACGTGCAGGAAAA
ACGGCGTTTGGTTTTAACGGAACACTAGAAAATATCAAATTCTTTAATAGTGCATTGGATGAAGAAACTGTTAAAAAGAT
GACAACAAACGCTGTTACTGGACATTTAATTTATACGGCTAATGATACAACAGGTTCTAACTATTTCCGTATTCCAGTTC
TGTATACTTTTAGCAATGGTCGGGTTTTTTCAAGCATTGACGCTCGTTACGGTGGAACTCATGATTTCTTGAATAAAATT
AATATTGCTACAAGTTATAGTGATGATAATGGTAAGACATGGACTAAACCAAAATTAACATTAGCATTCGATGATTTTGC
GCCAGCACCATTAGAATGGCCTCGTGATGTTGGTGGACGTGACTTACAAATCAGCGGTGGTGCAACCTATATTGACTCTG
TTATTGTTGAAAAAAATAACAAACAAGTACTCATGTTTGCTGATGTTATGCCTGCTGGAGTAAGTTTTAGAGAAGCTACT
AGAAAAGATTCAGGTTATAAACAAATTGATGGTAATTATTACCTTAAATTAAAGAAACAAGGTGATACTGATTATAATTA
TACTATTCGTGAGCATGGTACTGTATACGACGATCGTACCAACAGACCAACTGAATTTTCAGTAGATAAAAATTTCGGTA
TTAAACAAAATGGTAATTATTTGACGGTAGAGCAATATTCGGTTTCATTTGAAAATAATAAAAAGACTGAATATCGTAAT
GGGACTCAAGTCCATATGAATATCTTCTACAAAGATGCATTATTCAAAGTAGTGCCAACGAACTATATTGCATATATTTC
TAGCAATGATCATGGCGAATCTTGGTCTGCACCAACTTTATTACCTCCTATAATGGGACTTAATCGGAATGCGCCTTATT
TGGGTCCTGGACGTGGAATCATTGAAAGCTCAACTGGACGTATTCTTATTCCGTCTTACACTGGTAAAGAGTCTGCATTC
ATTTATAGTGACGATAATGGAGCGTCTTGGAAAGTTAAAGTTGTGCCACTTCCTTCTAGTTGGTCAGCAGAAGCACAATT
TGTAGAATTGAGTCCAGGAGTAATTCAAGCATACATGCGTACAAATAATGGTAAAATTGCATATTTAACAAGTAAAGATG
CAGGTACTACTTGGAGTGCGCCGGAATATTTGAAATTTGTTTCAAATCCAAGTTATGGAACACAATTATCAATCATCAAT
TATAGTCAATTGATTGATGGTAAAAAGGCTGTCATTTTAAGTACTCCAAACTCCACAAATGGTCGTAAACACGGACAAAT
TTCGATTGGTCTAATTAATGATGATAATACAATTGATTGGCGTTATCATCACGATGTTGATTATAGTAACTATGGATACT
CATATTCAACATTGACAGAGTTACCAAATCATGAAATTGGATTGATGTTTGAAAAATTTGATTCATGGTCTCGTAATGAA
CTTCATATGAAAAATGTTGTACCATATATAACATTTAAGATTGAAGATTTGAAAAAGAATTAA

Upstream 100 bases:

>100_bases
TTGGTGACTTTTGAAGAAGATCTTCACCAACCAAAGATTCATTGCAATGATGAAACTGTTAAAAAACTTGTTATCAAAGT
TTTAAACGAGGAAAAATAAA

Downstream 100 bases:

>100_bases
AGCTGAAATTTAAAAATATATAGAAAGAGGATAAAAATTATGGTAAATTACGGTATTGTTGGAGCTGGATATTTTGGAGC
TGATTTGGCTCGCTCAATGA

Product: sialidase (neuraminidase)

Products: NA

Alternate protein names: Neuraminidase B [H]

Number of amino acids: Translated: 740; Mature: 740

Protein sequence:

>740_residues
MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPELVQPVAPTTSISEVQHKSGNSSEVTVQPRTVETTVKDPSST
AEETPVLEKNNVTLTGGGENVTNELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
RDTSSNKNHLVTRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNFLNIKDIKGIDYYMLGGVKRAGK
TAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHLIYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKI
NIATSYSDDNGKTWTKPKLTLAFDDFAPAPLEWPRDVGGRDLQISGGATYIDSVIVEKNNKQVLMFADVMPAGVSFREAT
RKDSGYKQIDGNYYLKLKKQGDTDYNYTIREHGTVYDDRTNRPTEFSVDKNFGIKQNGNYLTVEQYSVSFENNKKTEYRN
GTQVHMNIFYKDALFKVVPTNYIAYISSNDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAF
IYSDDNGASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYLKFVSNPSYGTQLSIIN
YSQLIDGKKAVILSTPNSTNGRKHGQISIGLINDDNTIDWRYHHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNE
LHMKNVVPYITFKIEDLKKN

Sequences:

>Translated_740_residues
MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPELVQPVAPTTSISEVQHKSGNSSEVTVQPRTVETTVKDPSST
AEETPVLEKNNVTLTGGGENVTNELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
RDTSSNKNHLVTRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNFLNIKDIKGIDYYMLGGVKRAGK
TAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHLIYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKI
NIATSYSDDNGKTWTKPKLTLAFDDFAPAPLEWPRDVGGRDLQISGGATYIDSVIVEKNNKQVLMFADVMPAGVSFREAT
RKDSGYKQIDGNYYLKLKKQGDTDYNYTIREHGTVYDDRTNRPTEFSVDKNFGIKQNGNYLTVEQYSVSFENNKKTEYRN
GTQVHMNIFYKDALFKVVPTNYIAYISSNDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAF
IYSDDNGASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYLKFVSNPSYGTQLSIIN
YSQLIDGKKAVILSTPNSTNGRKHGQISIGLINDDNTIDWRYHHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNE
LHMKNVVPYITFKIEDLKKN
>Mature_740_residues
MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPELVQPVAPTTSISEVQHKSGNSSEVTVQPRTVETTVKDPSST
AEETPVLEKNNVTLTGGGENVTNELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
RDTSSNKNHLVTRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNFLNIKDIKGIDYYMLGGVKRAGK
TAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHLIYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKI
NIATSYSDDNGKTWTKPKLTLAFDDFAPAPLEWPRDVGGRDLQISGGATYIDSVIVEKNNKQVLMFADVMPAGVSFREAT
RKDSGYKQIDGNYYLKLKKQGDTDYNYTIREHGTVYDDRTNRPTEFSVDKNFGIKQNGNYLTVEQYSVSFENNKKTEYRN
GTQVHMNIFYKDALFKVVPTNYIAYISSNDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAF
IYSDDNGASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYLKFVSNPSYGTQLSIIN
YSQLIDGKKAVILSTPNSTNGRKHGQISIGLINDDNTIDWRYHHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNE
LHMKNVVPYITFKIEDLKKN

Specific function: Unknown

COG id: COG4409

COG function: function code G; Neuraminidase (sialidase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 BNR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002860
- InterPro:   IPR008985
- InterPro:   IPR013320
- InterPro:   IPR004124
- InterPro:   IPR011040 [H]

Pfam domain/function: PF02012 BNR; PF02973 Sialidase [H]

EC number: =3.2.1.18 [H]

Molecular weight: Translated: 82301; Mature: 82301

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPELVQPVAPTTSISEVQHKSGNS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCHHHHHHCCCCC
SEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVTNELKDKFTSGDFTVVIKY
CEEEECCCEEEEEECCCCCCHHHCCCEECCCEEEECCCCHHHHHHHHHCCCCCEEEEEEE
NQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEARDTSSNKNHLVTRPASVWGK
CCCCHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCEECCCCCCCCEEEECCHHHHHH
YKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNFLNIKDIKGIDYYMLGGVKRAGK
HHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHCCCCEEECCCCCEEEECCCCCCCC
TAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHLIYTANDTTGSNYFRIPVLYTFSNG
EECCCCCCHHHHHHHHHHCCHHHHHHHHHCCEEEEEEEEECCCCCCCEEEEEEEEEECCC
RVFSSIDARYGGTHDFLNKINIATSYSDDNGKTWTKPKLTLAFDDFAPAPLEWPRDVGGR
EEEEECCCCCCCCHHHHHHEEEEEEECCCCCCEECCCEEEEEECCCCCCCCCCCCCCCCC
DLQISGGATYIDSVIVEKNNKQVLMFADVMPAGVSFREATRKDSGYKQIDGNYYLKLKKQ
EEEECCCCEEEEEEEEECCCCEEEEEECCCCCCCCHHHHHCCCCCCEEECCCEEEEEEEC
GDTDYNYTIREHGTVYDDRTNRPTEFSVDKNFGIKQNGNYLTVEQYSVSFENNKKTEYRN
CCCCEEEEEEECCEEEECCCCCCCEEEECCCCCEECCCCEEEEEEEEEEECCCCCCCCCC
GTQVHMNIFYKDALFKVVPTNYIAYISSNDHGESWSAPTLLPPIMGLNRNAPYLGPGRGI
CCEEEEEEEEECEEEEEECCEEEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCE
IESSTGRILIPSYTGKESAFIYSDDNGASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMR
EECCCCCEEEECCCCCCCEEEEECCCCCEEEEEEEECCCCCCCCEEEEEECCCEEEEEEE
TNNGKIAYLTSKDAGTTWSAPEYLKFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTN
ECCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCEEEEEEHHHHCCCCEEEEEECCCCCC
GRKHGQISIGLINDDNTIDWRYHHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNE
CCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCC
LHMKNVVPYITFKIEDLKKN
EECCCCCEEEEEEEEECCCC
>Mature Secondary Structure
MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPELVQPVAPTTSISEVQHKSGNS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCHHHHHHCCCCC
SEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVTNELKDKFTSGDFTVVIKY
CEEEECCCEEEEEECCCCCCHHHCCCEECCCEEEECCCCHHHHHHHHHCCCCCEEEEEEE
NQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEARDTSSNKNHLVTRPASVWGK
CCCCHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCEECCCCCCCCEEEECCHHHHHH
YKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNFLNIKDIKGIDYYMLGGVKRAGK
HHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHCCCCEEECCCCCEEEECCCCCCCC
TAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHLIYTANDTTGSNYFRIPVLYTFSNG
EECCCCCCHHHHHHHHHHCCHHHHHHHHHCCEEEEEEEEECCCCCCCEEEEEEEEEECCC
RVFSSIDARYGGTHDFLNKINIATSYSDDNGKTWTKPKLTLAFDDFAPAPLEWPRDVGGR
EEEEECCCCCCCCHHHHHHEEEEEEECCCCCCEECCCEEEEEECCCCCCCCCCCCCCCCC
DLQISGGATYIDSVIVEKNNKQVLMFADVMPAGVSFREATRKDSGYKQIDGNYYLKLKKQ
EEEECCCCEEEEEEEEECCCCEEEEEECCCCCCCCHHHHHCCCCCCEEECCCEEEEEEEC
GDTDYNYTIREHGTVYDDRTNRPTEFSVDKNFGIKQNGNYLTVEQYSVSFENNKKTEYRN
CCCCEEEEEEECCEEEECCCCCCCEEEECCCCCEECCCCEEEEEEEEEEECCCCCCCCCC
GTQVHMNIFYKDALFKVVPTNYIAYISSNDHGESWSAPTLLPPIMGLNRNAPYLGPGRGI
CCEEEEEEEEECEEEEEECCEEEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCE
IESSTGRILIPSYTGKESAFIYSDDNGASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMR
EECCCCCEEEECCCCCCCEEEEECCCCCEEEEEEEECCCCCCCCEEEEEECCCEEEEEEE
TNNGKIAYLTSKDAGTTWSAPEYLKFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTN
ECCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCEEEEEEHHHHCCCCEEEEEECCCCCC
GRKHGQISIGLINDDNTIDWRYHHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNE
CCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCC
LHMKNVVPYITFKIEDLKKN
EECCCCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759848; 11463916 [H]