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The map label for this gene is ntpI [H]

Identifier: 221231997

GI number: 221231997

Start: 1180518

End: 1182509

Strand: Reverse

Name: ntpI [H]

Synonym: SPN23F_12140

Alternate gene names: 221231997

Gene position: 1182509-1180518 (Counterclockwise)

Preceding gene: 221231998

Following gene: 221231996

Centisome position: 53.23

GC content: 31.93

Gene sequence:

>1992_bases
ATGGCTATTAGTCAGATGAAAAGAATTTCTCTACTATTTACTAAGAGTAGTCTTGATGATGTTTTAAAAACTATTCAAGA
ACTAGAGTCAGTGCAGTTCCGTGATTTAAAGGTTCAGGATAACTGGTCAGAAGCGCTAGAAAAAGATGAGGTTGTATTTT
CAACTATTCAAATTTCTCACACTTCTAATTCCCATCATGGGGTTATTGAAGGAAATGATGCCTTGAATTATTTGATGAAT
AAACAACAACATTTGGAAGCAACTGTAGAGAAATTACAAGAATACCTACCGAAAGAAAACACGTTTAAGTTATTACAGCA
ACCTCCGATAACAACCTCTTATGAAGAATTAGAAAAATTTGGTAAAGCTAATGTTGCTGAGGGTGTTCTTAAAAAAGTGA
ATCATCAAATAAACAGAGTTCATGAATTAGAAAGAAACATTCAAAGTAATAATGAGGAAATAGAGAGATTAATAAAGTGG
GAAAAATTAGAAATTATTCCTGCGCATTTAGAACAATTTTCTTTCTGTAGAGGAAAAGTCGGAACAATTCCAAGGACTGT
AGATAATCGCTTATACAATAATTTTTTAGAAAACAATATTGAAGTTCAAGAAATATTTTCTAATGATAGAGAGTACGGTG
TTGTTGTTTTCTATCAGTCCAGTTGCTCTATTGATTTTGATGAATACTTATTTGAACCATTTGATTATTCTAGAAAGGAA
TTACCGAAGCAGCGAGTAGTAGATTTGGATCAAGAAAACATGCAGTTAATAACTGAAAAAGAGAATATTATCGCATCGTT
GCAAGATTCAAAGAAAAATTTGATAGATTTACAATGGCAAATTGACTATATTTTATCTATCTATGCTCGTCAAATCTCTA
AGAATAACCTTTTGAGCACTCCGCATCTAGTTGCATTAGAAGGATGGATAGAAGAAACTCGTATTTTATATTTTATAAAA
GTTATGGATGAGCGTTTTGGACATTCTATTTATATTTATGAATCGGAAACATTGTCGGATAATCAAGATGAAATACCTAT
CAAATTAACGAATCACTCTTTAATTGAACCATTTGAATTATTGACAGAAATGTATGCTCTGCCCAAATATTATGAGAAAG
ATCCTACACCTGTATTAGCACCATTTTACTTTACATTTTTTGGAATGATGGTTGCTGATTTAGGCTATGGTTTACTATTG
TTTTTAGGAATAATGTTAGCATTAAAAATTTTTCATCTACCTTCAGTAACTAAGAAATTTTTAAAATTCTTTAATATATT
AGGGGTAGCCGTTGCAATTTGGGGTGGAATCTATGGCTCATTTTTTGGATATGAGTTGCCATTTCATCTGATAACTACAA
CCTCGGATGTCATGACTATATTAGTAGTGTCAGTTGTGTTTGGATTTATTACAGTATTTGTAGGTTTGTTAGCTTCAGGA
CTACAAAAAGTAAGAATGAAGAAATATGCAGAAGCATATAATTCAGGATTTGCGTGGTGTGTTATTCTGCTTGGCTTGTT
ATTTATTGCTGTCGGAATGTTGATGCCTGATATTAGACCGTTATTTGTATTAGGGAAATGGGTATCTATTTTTAATGCTG
TGGGGATTTTGATTGCTTCTATTATTCAAGCCAAAAGCTTGTCAGGTATTGGCTCAGGATTGTTTAATCTATATAACATT
TCATCTTATATAGGTGATTTAGTTAGTTTCACTCGATTGATGGCATTAGGATTATCTGGAGCAAGTATAGCATCAGCTTT
CAATTTAATTGTTGGTTTGTTTCCGGGGACATTGGCTAAACTGACAATTGGATTAGTATTATTCATTCTTTTACATGCGA
TCAATATTTTTCTATCGTTACTATCAGGATATGTTCATGGAGCGCGTCTGATATTTGTTGAATTTTTTGGTAAGTTTTAT
GAGGGTGGAGGAAAACCATTTCAACCTTTGAAGGCTTCTGAGAAATATATTAAGGTTATTACAAAGAATTAA

Upstream 100 bases:

>100_bases
AATAAAACAATCAAGGAAAATGATGCAAAGATTCAGTATATTTCATCAAGTAGGAGAGGAGAATTTGTAGAAAAAATTAT
TGGTAGGGTGGTAGAAAAAT

Downstream 100 bases:

>100_bases
TGGAGGATATATATAATGGAACATTTAGCAACTTATTTTTCAACCTATGGAGGAGCTTTCTTCGCTGCATTGGGAATTGT
ATTGGCGGTTGGATTAAGCG

Product: V-type ATP synthase subunit I

Products: ADP; phosphate; H+

Alternate protein names: Na(+)-translocating ATPase subunit I; V-type sodium pump subunit I [H]

Number of amino acids: Translated: 663; Mature: 662

Protein sequence:

>663_residues
MAISQMKRISLLFTKSSLDDVLKTIQELESVQFRDLKVQDNWSEALEKDEVVFSTIQISHTSNSHHGVIEGNDALNYLMN
KQQHLEATVEKLQEYLPKENTFKLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERNIQSNNEEIERLIKW
EKLEIIPAHLEQFSFCRGKVGTIPRTVDNRLYNNFLENNIEVQEIFSNDREYGVVVFYQSSCSIDFDEYLFEPFDYSRKE
LPKQRVVDLDQENMQLITEKENIIASLQDSKKNLIDLQWQIDYILSIYARQISKNNLLSTPHLVALEGWIEETRILYFIK
VMDERFGHSIYIYESETLSDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVADLGYGLLL
FLGIMLALKIFHLPSVTKKFLKFFNILGVAVAIWGGIYGSFFGYELPFHLITTTSDVMTILVVSVVFGFITVFVGLLASG
LQKVRMKKYAEAYNSGFAWCVILLGLLFIAVGMLMPDIRPLFVLGKWVSIFNAVGILIASIIQAKSLSGIGSGLFNLYNI
SSYIGDLVSFTRLMALGLSGASIASAFNLIVGLFPGTLAKLTIGLVLFILLHAINIFLSLLSGYVHGARLIFVEFFGKFY
EGGGKPFQPLKASEKYIKVITKN

Sequences:

>Translated_663_residues
MAISQMKRISLLFTKSSLDDVLKTIQELESVQFRDLKVQDNWSEALEKDEVVFSTIQISHTSNSHHGVIEGNDALNYLMN
KQQHLEATVEKLQEYLPKENTFKLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERNIQSNNEEIERLIKW
EKLEIIPAHLEQFSFCRGKVGTIPRTVDNRLYNNFLENNIEVQEIFSNDREYGVVVFYQSSCSIDFDEYLFEPFDYSRKE
LPKQRVVDLDQENMQLITEKENIIASLQDSKKNLIDLQWQIDYILSIYARQISKNNLLSTPHLVALEGWIEETRILYFIK
VMDERFGHSIYIYESETLSDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVADLGYGLLL
FLGIMLALKIFHLPSVTKKFLKFFNILGVAVAIWGGIYGSFFGYELPFHLITTTSDVMTILVVSVVFGFITVFVGLLASG
LQKVRMKKYAEAYNSGFAWCVILLGLLFIAVGMLMPDIRPLFVLGKWVSIFNAVGILIASIIQAKSLSGIGSGLFNLYNI
SSYIGDLVSFTRLMALGLSGASIASAFNLIVGLFPGTLAKLTIGLVLFILLHAINIFLSLLSGYVHGARLIFVEFFGKFY
EGGGKPFQPLKASEKYIKVITKN
>Mature_662_residues
AISQMKRISLLFTKSSLDDVLKTIQELESVQFRDLKVQDNWSEALEKDEVVFSTIQISHTSNSHHGVIEGNDALNYLMNK
QQHLEATVEKLQEYLPKENTFKLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERNIQSNNEEIERLIKWE
KLEIIPAHLEQFSFCRGKVGTIPRTVDNRLYNNFLENNIEVQEIFSNDREYGVVVFYQSSCSIDFDEYLFEPFDYSRKEL
PKQRVVDLDQENMQLITEKENIIASLQDSKKNLIDLQWQIDYILSIYARQISKNNLLSTPHLVALEGWIEETRILYFIKV
MDERFGHSIYIYESETLSDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVADLGYGLLLF
LGIMLALKIFHLPSVTKKFLKFFNILGVAVAIWGGIYGSFFGYELPFHLITTTSDVMTILVVSVVFGFITVFVGLLASGL
QKVRMKKYAEAYNSGFAWCVILLGLLFIAVGMLMPDIRPLFVLGKWVSIFNAVGILIASIIQAKSLSGIGSGLFNLYNIS
SYIGDLVSFTRLMALGLSGASIASAFNLIVGLFPGTLAKLTIGLVLFILLHAINIFLSLLSGYVHGARLIFVEFFGKFYE
GGGKPFQPLKASEKYIKVITKN

Specific function: Involved in ATP-driven sodium extrusion [H]

COG id: COG1269

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase 116 kDa subunit family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002490 [H]

Pfam domain/function: PF01496 V_ATPase_I [H]

EC number: 3.6.3.14

Molecular weight: Translated: 75488; Mature: 75357

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISQMKRISLLFTKSSLDDVLKTIQELESVQFRDLKVQDNWSEALEKDEVVFSTIQISH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCEEECCCHHHHHCCCCCEEEEEEEEE
TSNSHHGVIEGNDALNYLMNKQQHLEATVEKLQEYLPKENTFKLLQQPPITTSYEELEKF
CCCCCCCEEECCHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHH
GKANVAEGVLKKVNHQINRVHELERNIQSNNEEIERLIKWEKLEIIPAHLEQFSFCRGKV
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GTIPRTVDNRLYNNFLENNIEVQEIFSNDREYGVVVFYQSSCSIDFDEYLFEPFDYSRKE
CCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEEEEECCCCCCHHHHHCCCCCCCHHH
LPKQRVVDLDQENMQLITEKENIIASLQDSKKNLIDLQWQIDYILSIYARQISKNNLLST
CCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCC
PHLVALEGWIEETRILYFIKVMDERFGHSIYIYESETLSDNQDEIPIKLTNHSLIEPFEL
CCCEEEHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCEEECCCCCCCHHHH
LTEMYALPKYYEKDPTPVLAPFYFTFFGMMVADLGYGLLLFLGIMLALKIFHLPSVTKKF
HHHHHHCCHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LKFFNILGVAVAIWGGIYGSFFGYELPFHLITTTSDVMTILVVSVVFGFITVFVGLLASG
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQKVRMKKYAEAYNSGFAWCVILLGLLFIAVGMLMPDIRPLFVLGKWVSIFNAVGILIAS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
IIQAKSLSGIGSGLFNLYNISSYIGDLVSFTRLMALGLSGASIASAFNLIVGLFPGTLAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHH
LTIGLVLFILLHAINIFLSLLSGYVHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEE
TKN
ECC
>Mature Secondary Structure 
AISQMKRISLLFTKSSLDDVLKTIQELESVQFRDLKVQDNWSEALEKDEVVFSTIQISH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCEEECCCHHHHHCCCCCEEEEEEEEE
TSNSHHGVIEGNDALNYLMNKQQHLEATVEKLQEYLPKENTFKLLQQPPITTSYEELEKF
CCCCCCCEEECCHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHH
GKANVAEGVLKKVNHQINRVHELERNIQSNNEEIERLIKWEKLEIIPAHLEQFSFCRGKV
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GTIPRTVDNRLYNNFLENNIEVQEIFSNDREYGVVVFYQSSCSIDFDEYLFEPFDYSRKE
CCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEEEEECCCCCCHHHHHCCCCCCCHHH
LPKQRVVDLDQENMQLITEKENIIASLQDSKKNLIDLQWQIDYILSIYARQISKNNLLST
CCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCC
PHLVALEGWIEETRILYFIKVMDERFGHSIYIYESETLSDNQDEIPIKLTNHSLIEPFEL
CCCEEEHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCEEECCCCCCCHHHH
LTEMYALPKYYEKDPTPVLAPFYFTFFGMMVADLGYGLLLFLGIMLALKIFHLPSVTKKF
HHHHHHCCHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LKFFNILGVAVAIWGGIYGSFFGYELPFHLITTTSDVMTILVVSVVFGFITVFVGLLASG
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQKVRMKKYAEAYNSGFAWCVILLGLLFIAVGMLMPDIRPLFVLGKWVSIFNAVGILIAS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
IIQAKSLSGIGSGLFNLYNISSYIGDLVSFTRLMALGLSGASIASAFNLIVGLFPGTLAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHH
LTIGLVLFILLHAINIFLSLLSGYVHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEE
TKN
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8157629; 8144530 [H]