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The map label for this gene is ntpD

Identifier: 221231990

GI number: 221231990

Start: 1174171

End: 1174782

Strand: Reverse

Name: ntpD

Synonym: SPN23F_12070

Alternate gene names: 221231990

Gene position: 1174782-1174171 (Counterclockwise)

Preceding gene: 221231991

Following gene: 221231989

Centisome position: 52.89

GC content: 30.88

Gene sequence:

>612_bases
ATGGTACGTTTGAATGTAAAACCAACTCGTATGGAATTGAATAACTTAAAGGAACGTTTGACAACAGCTGAACGTGGACA
TAAGTTATTAAAGGATAAAAGAGATGAATTGATGAGGCGATTTATTTCTTTGATTCGTGAGAATAATCAACTTCGGAAAG
AAGTGGAAAGTTATCTAATTGATAATCTAAAATCCTTTGCAGTTGCTAAATCATTAAAGAATTCTCAAATGGTGGAGGAA
TTATTTTCAATTCCATCGAAAGAAATTGAATTATTTGTTGAGAAAGAAAATATCATGAGTGTAACAGTTCCTAGAATGCA
TATGAATATTACTTCTCAAAATGAGAACAGTGAATACAGCTATTTATCTTCTAATAGTGAAATGGATGATGTATTTGCTA
CAATGAATAGTTTAATTTATAAATTACTAAGACTGGCAGAAGTTGAAAAAACGTGTCAGTTAATGGCTGATGAAATAGAA
AAAACACGTAGACGTGTAAATGGTTTAGAATACTCGATTATTCCAAACTTGTCGGAAACTATTCATTATATAGAATTGAA
ACTAGAGGAGGCAGAAAGAGCCAATTTAGTTCGTATTATGAAAGTGAAGTAG

Upstream 100 bases:

>100_bases
TCAATTCTTCCTAGAACAGAGTTAAAACGTATCAAAGATGATTTGCTTGATAAATACTTACCTTTGGTAGAAGTTTAATC
CGGAAATGGAGTGATTATCT

Downstream 100 bases:

>100_bases
ATCCTTTATTTAGATTATTAATTAGATGAACAAATATCAGCTTGGATAAGGCTTTAAGCCTTTCTAAGCTTTTTTTATTG
ACAGTATCAGGATATCTTTT

Product: V-type ATP synthase subunit D

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit D

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISLIRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEE
LFSIPSKEIELFVEKENIMSVTVPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIE
KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK

Sequences:

>Translated_203_residues
MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISLIRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEE
LFSIPSKEIELFVEKENIMSVTVPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIE
KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK
>Mature_203_residues
MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISLIRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEE
LFSIPSKEIELFVEKENIMSVTVPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIE
KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG1394

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase D subunit family

Homologues:

Organism=Homo sapiens, GI7706757, Length=208, Percent_Identity=26.4423076923077, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17553636, Length=205, Percent_Identity=30.2439024390244, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20128937, Length=207, Percent_Identity=28.0193236714976, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355551, Length=211, Percent_Identity=29.3838862559242, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VATD_STRP4 (B5E550)

Other databases:

- EMBL:   CP001015
- RefSeq:   YP_002037916.1
- EnsemblBacteria:   EBSTRT00000022005
- GeneID:   6479288
- GenomeReviews:   CP001015_GR
- KEGG:   spx:SPG_1208
- GeneTree:   EBGT00050000029439
- HOGENOM:   HBG732046
- OMA:   GEVMKEA
- ProtClustDB:   PRK00373
- HAMAP:   MF_00271
- InterPro:   IPR002699
- PANTHER:   PTHR11671
- TIGRFAMs:   TIGR00309

Pfam domain/function: PF01813 ATP-synt_D

EC number: 3.6.3.14

Molecular weight: Translated: 23918; Mature: 23918

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISLIRENNQLRKEVESYLI
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
DNLKSFAVAKSLKNSQMVEELFSIPSKEIELFVEKENIMSVTVPRMHMNITSQNENSEYS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCEEEEEECHHEEEEECCCCCCCCH
YLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIEKTRRRVNGLEYSIIPNLSET
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHH
IHYIELKLEEAERANLVRIMKVK
HHHHHEEHHHHHHCCEEEEEECC
>Mature Secondary Structure
MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISLIRENNQLRKEVESYLI
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
DNLKSFAVAKSLKNSQMVEELFSIPSKEIELFVEKENIMSVTVPRMHMNITSQNENSEYS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCEEEEEECHHEEEEECCCCCCCCH
YLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIEKTRRRVNGLEYSIIPNLSET
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHH
IHYIELKLEEAERANLVRIMKVK
HHHHHEEHHHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11442348