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The map label for this gene is glnM [H]

Identifier: 221231431

GI number: 221231431

Start: 533031

End: 533708

Strand: Reverse

Name: glnM [H]

Synonym: SPN23F_05480

Alternate gene names: 221231431

Gene position: 533708-533031 (Counterclockwise)

Preceding gene: 221231432

Following gene: 221231430

Centisome position: 24.03

GC content: 43.36

Gene sequence:

>678_bases
ATGACAGATTTATCATCTTGGACAGCCTATTTTCAGGATTTTGGACAATTTTTCAATGGTTTCCTCTTTACTCTTGCCCT
AGCGATTGGATTCTTTATCCTCGCCATGGTCTTAGGAATCTTCTTTGGTGCCATGTCAACCAGTAAACGTCCAATTTTAC
GCATTTTAGCTCACATCTTTGTGGAATTTTACCAAAACACTCCCCTCTTGGTGCAGTTTGTTATTGTTTTTTATGGCCTA
CCTCTTATCAGTGACCATACTATCATGATTCCAATTTATTGGACAGCTGTTCTCTGCGTGGGACTCTATCACGGCGCTTA
TATCGCTGAGGTTATTCGTTCAGGGATTCAGTCTATTCCTAGTGGTCAGATGGAGGCCGCCTTGTCGCAAGGTTTTACCT
ATATCAGTGCCATGCGCTTGATTACCTTGCCTCAGGCCTTCCGCATCATTCTCCCTCCATTGACCAACCAAATTGTTAAC
CTCATCAAGAACACATCTACTGTAGCTATCATCTCTGGAGTAGACTTGATGTTTGTGACTAAGTCTTGGTCGGCTCTCAA
CGGAAACTATATCCCAGCCTTTTTAGGTGCTGCTCTTCTCTACTTTGCCCTATGCTTCCCTGTTGCCCAGTTTGGTCGCA
AGATGGAGCAAGCCAATAAAAAAGCCTATTCACTTTAG

Upstream 100 bases:

>100_bases
CTTGGTTACTAAATGGAGCAAGGATGGTAGTTTGCAGAAACTTTATGACCGTTACAAGCTCAAACCATCTAGCCATACTG
CAGATTAAGGAGGACACCCC

Downstream 100 bases:

>100_bases
GAGGTTACTATGGAATCTATTTTAGAAATTTTAACCCCAGATAACCTAGTCTTTATCTTTAAAGGATTTGGCTTGACCCT
CTATATTTCTCTGATTGCCA

Product: amino acid ABC transporter permease

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTDLSSWTAYFQDFGQFFNGFLFTLALAIGFFILAMVLGIFFGAMSTSKRPILRILAHIFVEFYQNTPLLVQFVIVFYGL
PLISDHTIMIPIYWTAVLCVGLYHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVN
LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQANKKAYSL

Sequences:

>Translated_225_residues
MTDLSSWTAYFQDFGQFFNGFLFTLALAIGFFILAMVLGIFFGAMSTSKRPILRILAHIFVEFYQNTPLLVQFVIVFYGL
PLISDHTIMIPIYWTAVLCVGLYHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVN
LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQANKKAYSL
>Mature_224_residues
TDLSSWTAYFQDFGQFFNGFLFTLALAIGFFILAMVLGIFFGAMSTSKRPILRILAHIFVEFYQNTPLLVQFVIVFYGLP
LISDHTIMIPIYWTAVLCVGLYHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVNL
IKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQANKKAYSL

Specific function: Part of the ABC transporter complex glnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786874, Length=173, Percent_Identity=35.8381502890173, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI87082239, Length=208, Percent_Identity=34.6153846153846, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1788226, Length=206, Percent_Identity=32.5242718446602, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787030, Length=215, Percent_Identity=27.906976744186, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1786873, Length=212, Percent_Identity=27.3584905660377, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI48994930, Length=90, Percent_Identity=43.3333333333333, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788645, Length=218, Percent_Identity=26.1467889908257, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787086, Length=178, Percent_Identity=26.4044943820225, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788646, Length=175, Percent_Identity=26.8571428571429, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1787087, Length=180, Percent_Identity=28.3333333333333, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25043; Mature: 24912

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLSSWTAYFQDFGQFFNGFLFTLALAIGFFILAMVLGIFFGAMSTSKRPILRILAHIF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCVGLYHGAYIAEVIRSGIQSIP
HHHHCCCHHHHHHHHHHHCCCHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVNLIKNTSTVAIISGVDLMFVT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCHHEEEE
KSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQANKKAYSL
CCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDLSSWTAYFQDFGQFFNGFLFTLALAIGFFILAMVLGIFFGAMSTSKRPILRILAHIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCVGLYHGAYIAEVIRSGIQSIP
HHHHCCCHHHHHHHHHHHCCCHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVNLIKNTSTVAIISGVDLMFVT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCHHEEEE
KSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQANKKAYSL
CCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 9384377 [H]