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The map label for this gene is blpA2 [H]

Identifier: 221231366

GI number: 221231366

Start: 470031

End: 470618

Strand: Reverse

Name: blpA2 [H]

Synonym: SPN23F_04820

Alternate gene names: 221231366

Gene position: 470618-470031 (Counterclockwise)

Preceding gene: 221231393

Following gene: 221231365

Centisome position: 21.19

GC content: 37.93

Gene sequence:

>588_bases
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Upstream 100 bases:

>100_bases
TTACCATTCAGGAAGTTTTAATGACTATTCAAGATTTCATAAAATATGAACTTAGTTTTATGACATAATAGACCTATCCA
CTATATGAAAGGAATTGCCA

Downstream 100 bases:

>100_bases
ATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCA
TGAGCTTCTCCAGAGATTAT

Product: bacteriocin transporter C39 protease domain BlpA2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Sequences:

>Translated_195_residues
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG
>Mature_194_residues
TSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVP
YPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPSS
DFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Specific function: Required for induction of competence. Seems to transport the competence-stimulating peptide (CSP) [H]

COG id: COG2274

COG function: function code V; ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 peptidase C39 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593
- InterPro:   IPR005897
- InterPro:   IPR005074 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran; PF03412 Peptidase_C39 [H]

EC number: NA

Molecular weight: Translated: 22271; Mature: 22140

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50990 PEPTIDASE_C39

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADE
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEEEHHHH
MGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKIT
CCCCCCCCCCCCEEECCCCCCCEEEEEECCCCCEEEEEEEEECCCCEEEEECCCCCEEEE
KMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPSSDFQTKISHCLHCSLKLIGH
EECCCEEEEEECCEEEEEEECCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
YYQYRWFLLSPRNLG
HEEEEEEEECCCCCC
>Mature Secondary Structure 
TSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEEEHHHH
MGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKIT
CCCCCCCCCCCCEEECCCCCCCEEEEEECCCCCEEEEEEEEECCCCEEEEECCCCCEEEE
KMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPSSDFQTKISHCLHCSLKLIGH
EECCCEEEEEECCEEEEEEECCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
YYQYRWFLLSPRNLG
HEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1987129; 11463916; 7883181 [H]