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The map label for this gene is muT4 [H]

Identifier: 221230935

GI number: 221230935

Start: 3249783

End: 3250538

Strand: Direct

Name: muT4 [H]

Synonym: MLBr_02698

Alternate gene names: 221230935

Gene position: 3249783-3250538 (Clockwise)

Preceding gene: 221230933

Following gene: 221230936

Centisome position: 99.44

GC content: 60.98

Gene sequence:

>756_bases
GTGCCAGCTATTATCGCTTGGGTGTCGGATGGCGAACAAGCCAAACCACGTCGGCGCCGAAAGCGACGGCGCGGTCGTGA
CGCCACGCGTTCAGCTGAGAACCACACAGACCGACAAGTGGCCAACGACGCAACCGCGACAAAACCGCGCCGCAGCCATT
CACCACATCGCGCACCCGAACAGCTGCGCACGGTGCACGAAACGTCCGCAGGAGGTCTAGTCATCTACGGTATCGACGGC
CCACGTGACGCCCAGGTTGCCGCTCTGATTGGTCGTATCGATCGACGAGGACGAATGCTTTGGTCGCTGCCCAAAGGGCA
TATCGAGCAAGGGGAGACCGCGGAGCAGACCGCTATCCGTGAGGTCGCCGAAGAGACAGGAATCCGCGGTAGCGTGCTCG
CCGCGCTGGGGCAAATCGACTACTGGTTCGTCACCGACGACTGTCGGGTGCATAAGACAGTACACCACTATTTGATGCGC
TTTTCTGGTGGTGAATTGTCCGACGACGACCTCGAGGTGACCGAAGTTGCTTGGGTGCCGATACGAGAACTGCCGTCCCG
CCTGGCCTACGCTGACGAACGCCGCCTGGCCGAGGTTGCCTACGAACTGATCAACAAGCTGCAAACCGGTGGTCCAGCCG
CGCTTCCACCGCTGCCACCCAGCTTGCCTCGGCGACAGTCGCAAACGCATTTCCGCACGCGTCATTCCAACAATTCCGCA
AACAGTCGGAAGAATGGTCACGGACAGGGGCCGTGA

Upstream 100 bases:

>100_bases
GTGCAACGGTGATCCAATCGATCCACTAAGTGACCCAGCCATGAACCTACTGTAACGCTGCGTACCTGACTAGCGGCGCG
CATGTCCTGAAGACCGGCTC

Downstream 100 bases:

>100_bases
CTGCATCGAGACTCCGGTTGGCCGGCTCGCTGAGCATTGCCTTAGTGGTCGACATCGTGGCTAGTTTTGCGGTGCTGCTC
GTCGCACCTACCGCCACGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MPAIIAWVSDGEQAKPRRRRKRRRGRDATRSAENHTDRQVANDATATKPRRSHSPHRAPEQLRTVHETSAGGLVIYGIDG
PRDAQVAALIGRIDRRGRMLWSLPKGHIEQGETAEQTAIREVAEETGIRGSVLAALGQIDYWFVTDDCRVHKTVHHYLMR
FSGGELSDDDLEVTEVAWVPIRELPSRLAYADERRLAEVAYELINKLQTGGPAALPPLPPSLPRRQSQTHFRTRHSNNSA
NSRKNGHGQGP

Sequences:

>Translated_251_residues
MPAIIAWVSDGEQAKPRRRRKRRRGRDATRSAENHTDRQVANDATATKPRRSHSPHRAPEQLRTVHETSAGGLVIYGIDG
PRDAQVAALIGRIDRRGRMLWSLPKGHIEQGETAEQTAIREVAEETGIRGSVLAALGQIDYWFVTDDCRVHKTVHHYLMR
FSGGELSDDDLEVTEVAWVPIRELPSRLAYADERRLAEVAYELINKLQTGGPAALPPLPPSLPRRQSQTHFRTRHSNNSA
NSRKNGHGQGP
>Mature_250_residues
PAIIAWVSDGEQAKPRRRRKRRRGRDATRSAENHTDRQVANDATATKPRRSHSPHRAPEQLRTVHETSAGGLVIYGIDGP
RDAQVAALIGRIDRRGRMLWSLPKGHIEQGETAEQTAIREVAEETGIRGSVLAALGQIDYWFVTDDCRVHKTVHHYLMRF
SGGELSDDDLEVTEVAWVPIRELPSRLAYADERRLAEVAYELINKLQTGGPAALPPLPPSLPRRQSQTHFRTRHSNNSAN
SRKNGHGQGP

Specific function: May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. In vitro has dATPase rather than 8-oxo-dGTPase activity [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 28084; Mature: 27953

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAIIAWVSDGEQAKPRRRRKRRRGRDATRSAENHTDRQVANDATATKPRRSHSPHRAPE
CCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCHH
QLRTVHETSAGGLVIYGIDGPRDAQVAALIGRIDRRGRMLWSLPKGHIEQGETAEQTAIR
HHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHH
EVAEETGIRGSVLAALGQIDYWFVTDDCRVHKTVHHYLMRFSGGELSDDDLEVTEVAWVP
HHHHHHCCCHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCEEHHEEECC
IRELPSRLAYADERRLAEVAYELINKLQTGGPAALPPLPPSLPRRQSQTHFRTRHSNNSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
NSRKNGHGQGP
CCCCCCCCCCC
>Mature Secondary Structure 
PAIIAWVSDGEQAKPRRRRKRRRGRDATRSAENHTDRQVANDATATKPRRSHSPHRAPE
CEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCHH
QLRTVHETSAGGLVIYGIDGPRDAQVAALIGRIDRRGRMLWSLPKGHIEQGETAEQTAIR
HHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHH
EVAEETGIRGSVLAALGQIDYWFVTDDCRVHKTVHHYLMRFSGGELSDDDLEVTEVAWVP
HHHHHHCCCHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCEEHHEEECC
IRELPSRLAYADERRLAEVAYELINKLQTGGPAALPPLPPSLPRRQSQTHFRTRHSNNSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
NSRKNGHGQGP
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]