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The map label for this gene is yafV [C]

Identifier: 221230801

GI number: 221230801

Start: 2924539

End: 2925354

Strand: Direct

Name: yafV [C]

Synonym: MLBr_02449

Alternate gene names: 221230801

Gene position: 2924539-2925354 (Clockwise)

Preceding gene: 221230793

Following gene: 221230802

Centisome position: 89.49

GC content: 63.36

Gene sequence:

>816_bases
ATGCGAATCGCATTGGCGCAAATCCTCAGCGGCACCGATCCGGTAGCAAACCTGCGGCTGGTGCGAGAGTACACAGGCCA
GGCCACCGACGCCGGCGCGACGTTAGTGGTCTTCCCGGAAGCGACCATGTGCCGATTCGGTGTTCCACTGGGGCCGGTCG
CTGAGCCCATAGACGGCCCCTGGGCCAACGGTGTGCGACAAATCGCGACCGAGGCCGGCATCACCATAATCGCCGGAATA
TTCACCCCCGCTGACGACGGGCGGGTAATGAACACGCTGATCGCTGCCGGCCCCGGGACACCCAACCAGCCCGACACCCA
CTACCACAAAATCCATCTCTACGACGCGTTCGGCTTCACTGAGTCACGGACGGTCACAGCCGGGCACGAACCGGTGGTGA
TCACAGTAGACGACGTCCAGGTTGGTCTCACTATTTGCTACGATATCCGCTTTCCAGCGCTGTACACTGAGCTGGCCCGC
CGCGGCGCGCAACTGATCGTGGTCTGCGCGTCATGGGGCTCCGGTGCTGGCAAACTCGAGCAGTGGACGTTGCTTGCCCG
TGCCCGTGCCCTTGACTCGATGAGCTACGTCGCCGCAGTCGGTCAGGCTGACCCAGGAGGTGCCCTGACCGACTCGGGCC
CCAGCTCAGCCGCACCGACCGGAGTAGGCGGCAGCCTGGTGGCCTCGCCGTTAGGCGAGGTGGTGGCGTCGGCTGGCACC
GAATCAAAACTGGTCGTCGCCGACATCGACGTCGACAACGTGACTACAGCTCGCGAGAACATCGCTGTACTGCGTAACCG
GTCACATTTTGCTTAG

Upstream 100 bases:

>100_bases
ACCCATCCAGAACAGCCTCGCTCTCCCTCGCAAGCGGGCAATACCCCTTACCCTCACACCGCAAGCGCCGCGCGGCGTAG
CCAAGCTTAAGCTGGCACGC

Downstream 100 bases:

>100_bases
GTTGATAGAGCACAATCACGTGGGTGACCAATCAGCAAGGACCACCGAATGAAGGCCCTTCGACGTGGGCGCATCCCAGC
TACCGGGGCCTCCTCAACCA

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MRIALAQILSGTDPVANLRLVREYTGQATDAGATLVVFPEATMCRFGVPLGPVAEPIDGPWANGVRQIATEAGITIIAGI
FTPADDGRVMNTLIAAGPGTPNQPDTHYHKIHLYDAFGFTESRTVTAGHEPVVITVDDVQVGLTICYDIRFPALYTELAR
RGAQLIVVCASWGSGAGKLEQWTLLARARALDSMSYVAAVGQADPGGALTDSGPSSAAPTGVGGSLVASPLGEVVASAGT
ESKLVVADIDVDNVTTARENIAVLRNRSHFA

Sequences:

>Translated_271_residues
MRIALAQILSGTDPVANLRLVREYTGQATDAGATLVVFPEATMCRFGVPLGPVAEPIDGPWANGVRQIATEAGITIIAGI
FTPADDGRVMNTLIAAGPGTPNQPDTHYHKIHLYDAFGFTESRTVTAGHEPVVITVDDVQVGLTICYDIRFPALYTELAR
RGAQLIVVCASWGSGAGKLEQWTLLARARALDSMSYVAAVGQADPGGALTDSGPSSAAPTGVGGSLVASPLGEVVASAGT
ESKLVVADIDVDNVTTARENIAVLRNRSHFA
>Mature_271_residues
MRIALAQILSGTDPVANLRLVREYTGQATDAGATLVVFPEATMCRFGVPLGPVAEPIDGPWANGVRQIATEAGITIIAGI
FTPADDGRVMNTLIAAGPGTPNQPDTHYHKIHLYDAFGFTESRTVTAGHEPVVITVDDVQVGLTICYDIRFPALYTELAR
RGAQLIVVCASWGSGAGKLEQWTLLARARALDSMSYVAAVGQADPGGALTDSGPSSAAPTGVGGSLVASPLGEVVASAGT
ESKLVVADIDVDNVTTARENIAVLRNRSHFA

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=274, Percent_Identity=32.8467153284672, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI297632350, Length=278, Percent_Identity=26.978417266187, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI297632348, Length=278, Percent_Identity=26.978417266187, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI5031947, Length=278, Percent_Identity=26.978417266187, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17556280, Length=281, Percent_Identity=29.1814946619217, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322335, Length=301, Percent_Identity=27.2425249169435, Blast_Score=92, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6323383, Length=286, Percent_Identity=27.6223776223776, Blast_Score=89, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21355835, Length=280, Percent_Identity=30, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17933642, Length=261, Percent_Identity=28.735632183908, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 28179; Mature: 28179

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIALAQILSGTDPVANLRLVREYTGQATDAGATLVVFPEATMCRFGVPLGPVAEPIDGP
CEEEHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHCCCCCCCCCCCCCCC
WANGVRQIATEAGITIIAGIFTPADDGRVMNTLIAAGPGTPNQPDTHYHKIHLYDAFGFT
HHHHHHHHHHHCCEEEEEEEECCCCCCCEEEHEEECCCCCCCCCCCCEEEEEEEEECCCC
ESRTVTAGHEPVVITVDDVQVGLTICYDIRFPALYTELARRGAQLIVVCASWGSGAGKLE
CCCEEECCCCCEEEEECCEEEEEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCCCCHH
QWTLLARARALDSMSYVAAVGQADPGGALTDSGPSSAAPTGVGGSLVASPLGEVVASAGT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
ESKLVVADIDVDNVTTARENIAVLRNRSHFA
CCEEEEEECCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRIALAQILSGTDPVANLRLVREYTGQATDAGATLVVFPEATMCRFGVPLGPVAEPIDGP
CEEEHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHCCCCCCCCCCCCCCC
WANGVRQIATEAGITIIAGIFTPADDGRVMNTLIAAGPGTPNQPDTHYHKIHLYDAFGFT
HHHHHHHHHHHCCEEEEEEEECCCCCCCEEEHEEECCCCCCCCCCCCEEEEEEEEECCCC
ESRTVTAGHEPVVITVDDVQVGLTICYDIRFPALYTELARRGAQLIVVCASWGSGAGKLE
CCCEEECCCCCEEEEECCEEEEEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCCCCHH
QWTLLARARALDSMSYVAAVGQADPGGALTDSGPSSAAPTGVGGSLVASPLGEVVASAGT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
ESKLVVADIDVDNVTTARENIAVLRNRSHFA
CCEEEEEECCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]