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The map label for this gene is desA1 [H]

Identifier: 221230645

GI number: 221230645

Start: 2599141

End: 2600157

Strand: Direct

Name: desA1 [H]

Synonym: MLBr_02185

Alternate gene names: 221230645

Gene position: 2599141-2600157 (Clockwise)

Preceding gene: 221230642

Following gene: 221230646

Centisome position: 79.53

GC content: 58.41

Gene sequence:

>1017_bases
ATGTCAGCCGAGCTGACCGACCTACAGCTGCTGCACGAGCTCGAACCGGTCGTGGAGAAGTACATGAACCGTCATGAACG
CCTACACAAGAACTGGAATCCGCACGACTATATCCCGTGGTCGGATGGCAAGAACTTCTACGCTCTCGGCGGTCAGGATT
GGGACCCCGAGCAGAGCCAGCTCTCCGATGTCGCCCAAGTAGCGATGGTACAGAACCTGGTCACCGAGGACAACCTGCCG
TCGTATCACCGAGAAATCGCGATGACCATGGGCATGGACGGTGCATGGGGGCAGTGGGTCAACCGCTGGACAGCCGAGGA
AAACCGGCACGGAATCGCGCTGCGCGACTATCTGGTGGTGACCCGCGCGGTCGATCCGGTGGAGCTAGAGAAACTACGCA
TCGAGGTAGTCAACCGGGGTTTCAGCCCGGGCCAGAATCACCAAGGCGGACTCTTCGCCGACACCCTGTTCGACTCGATC
CTCTACGTCACATTCCAGGAGCTGGCTACCCGCGTCTCGCACCGCAACACGGGTAAGGCCTGCAACGAGACGATCGCTGA
CCAGCTGCTCGCTAAAATATCGAGCGATGAAAACCTGCACATGATCTTCTACCGGGACGTCAGCGAAGCTGGCATAGAGC
TCGCACCCAACCTTGCGATCAAGGCACTGCACAAGATCCTGCACAACTTTAAGATGCCGGGATTCCTGGTTCCTGAGTTC
CGGCGTAAGGCCGTGATAATTGCCGTCGGTGGCGTCTACGACATTCGGATCCACCTTGACGAGGTGGTCATGCCGGTGCT
CAAAAAATGGCGGATCTTGGAGCGCGAAGACTTCAGCGGCGAGGGTACACGGTTGCGTGACGAAATCGGCGAGCATCTTA
CAGAGCTTGAGGCCGCGTGCGACAAGTTCGAAGTCTCCAAGCAGCGCTACATTGAACGCGAAGCCCGCCGGACTGAGAAA
ATCACCGCACGCAAGGTGCTATCTACCGAAGGCACGCTGAGGATGAGTGGGCGGTAG

Upstream 100 bases:

>100_bases
CGGTAACCCCACGACGTGGCATGCCGGAAGGGAACTTGATGCTACCGAGATACACAGATATGTTGACTGCAACCAATAGA
CACAGATAACTGGAGGAGCC

Downstream 100 bases:

>100_bases
TTGACCATTGCGCATCGGCCCGATAGAGCTTACCAGCCCGGTTGTGTTGGCTCCGATGGCCGGAGTAACGAACGTCACAT
TCCGGACACTGTGCCGTGAA

Product: acyl-[ACP] desaturase

Products: NA

Alternate protein names: DES; Putative acyl-ACP desaturase desA1 [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSAELTDLQLLHELEPVVEKYMNRHERLHKNWNPHDYIPWSDGKNFYALGGQDWDPEQSQLSDVAQVAMVQNLVTEDNLP
SYHREIAMTMGMDGAWGQWVNRWTAEENRHGIALRDYLVVTRAVDPVELEKLRIEVVNRGFSPGQNHQGGLFADTLFDSI
LYVTFQELATRVSHRNTGKACNETIADQLLAKISSDENLHMIFYRDVSEAGIELAPNLAIKALHKILHNFKMPGFLVPEF
RRKAVIIAVGGVYDIRIHLDEVVMPVLKKWRILEREDFSGEGTRLRDEIGEHLTELEAACDKFEVSKQRYIEREARRTEK
ITARKVLSTEGTLRMSGR

Sequences:

>Translated_338_residues
MSAELTDLQLLHELEPVVEKYMNRHERLHKNWNPHDYIPWSDGKNFYALGGQDWDPEQSQLSDVAQVAMVQNLVTEDNLP
SYHREIAMTMGMDGAWGQWVNRWTAEENRHGIALRDYLVVTRAVDPVELEKLRIEVVNRGFSPGQNHQGGLFADTLFDSI
LYVTFQELATRVSHRNTGKACNETIADQLLAKISSDENLHMIFYRDVSEAGIELAPNLAIKALHKILHNFKMPGFLVPEF
RRKAVIIAVGGVYDIRIHLDEVVMPVLKKWRILEREDFSGEGTRLRDEIGEHLTELEAACDKFEVSKQRYIEREARRTEK
ITARKVLSTEGTLRMSGR
>Mature_337_residues
SAELTDLQLLHELEPVVEKYMNRHERLHKNWNPHDYIPWSDGKNFYALGGQDWDPEQSQLSDVAQVAMVQNLVTEDNLPS
YHREIAMTMGMDGAWGQWVNRWTAEENRHGIALRDYLVVTRAVDPVELEKLRIEVVNRGFSPGQNHQGGLFADTLFDSIL
YVTFQELATRVSHRNTGKACNETIADQLLAKISSDENLHMIFYRDVSEAGIELAPNLAIKALHKILHNFKMPGFLVPEFR
RKAVIIAVGGVYDIRIHLDEVVMPVLKKWRILEREDFSGEGTRLRDEIGEHLTELEAACDKFEVSKQRYIEREARRTEKI
TARKVLSTEGTLRMSGR

Specific function: Could be involved in mycobacterial fatty acid biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005067
- InterPro:   IPR009078
- InterPro:   IPR012348 [H]

Pfam domain/function: PF03405 FA_desaturase_2 [H]

EC number: NA

Molecular weight: Translated: 38877; Mature: 38746

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAELTDLQLLHELEPVVEKYMNRHERLHKNWNPHDYIPWSDGKNFYALGGQDWDPEQSQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCHHH
LSDVAQVAMVQNLVTEDNLPSYHREIAMTMGMDGAWGQWVNRWTAEENRHGIALRDYLVV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHH
TRAVDPVELEKLRIEVVNRGFSPGQNHQGGLFADTLFDSILYVTFQELATRVSHRNTGKA
HHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
CNETIADQLLAKISSDENLHMIFYRDVSEAGIELAPNLAIKALHKILHNFKMPGFLVPEF
HHHHHHHHHHHHHCCCCCEEEEEEECHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
RRKAVIIAVGGVYDIRIHLDEVVMPVLKKWRILEREDFSGEGTRLRDEIGEHLTELEAAC
CCCEEEEEECCEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
DKFEVSKQRYIEREARRTEKITARKVLSTEGTLRMSGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
>Mature Secondary Structure 
SAELTDLQLLHELEPVVEKYMNRHERLHKNWNPHDYIPWSDGKNFYALGGQDWDPEQSQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCHHH
LSDVAQVAMVQNLVTEDNLPSYHREIAMTMGMDGAWGQWVNRWTAEENRHGIALRDYLVV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHH
TRAVDPVELEKLRIEVVNRGFSPGQNHQGGLFADTLFDSILYVTFQELATRVSHRNTGKA
HHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
CNETIADQLLAKISSDENLHMIFYRDVSEAGIELAPNLAIKALHKILHNFKMPGFLVPEF
HHHHHHHHHHHHHCCCCCEEEEEEECHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
RRKAVIIAVGGVYDIRIHLDEVVMPVLKKWRILEREDFSGEGTRLRDEIGEHLTELEAAC
CCCEEEEEECCEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
DKFEVSKQRYIEREARRTEKITARKVLSTEGTLRMSGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]