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The map label for this gene is aao [H]

Identifier: 221230566

GI number: 221230566

Start: 2403414

End: 2404376

Strand: Direct

Name: aao [H]

Synonym: MLBr_02011

Alternate gene names: 221230566

Gene position: 2403414-2404376 (Clockwise)

Preceding gene: 221230565

Following gene: 221230570

Centisome position: 73.54

GC content: 62.41

Gene sequence:

>963_bases
ATGGCAAGTAACGGGCAACAAATTGTCGTCATTGGTGCCGGCGTGAGTGGCTTAACATCGGCCGTCTGTCTGGCCGAAGC
GGGATGGCCGGTGCAGCTGTGGGCTGCCGCAATGCCACAGCAGACGACCTCCGCGGTGGCGGGGGCGGTATGGGCACCGC
CACGGCCAGAGGAACGTGCCTCTACATCGCTGGCTTGGACAGGACACTCACTGCAGATATTTCGTGAACTGGCTAACGAC
CCCAGCACCGGGGTGCGTATGGCGCCAGCGTTGACCGTTGGCGATTTACCCGGGGCGAACGCGATGGGGCTTGCTGCCAA
GCTGATCCCCGACCTGCGGCCGGCGGACCTGGCCGATCTCCCTGACGGCTTCGGTGCCGGGTTTTTCGGCACCATGCCAA
TGATCGATATGCCCCAATACCTCGATTACCTGACAGCGCGACTGGCGGCAGCCGGCTGCGAACTCGAAACTCGTTCAGTA
CGGTCGCTAGCTGAGGCCGCAGACACTGCACCGATAATTGTTAACTGCACTGGTCTCGGCGCAGCAGCCCTCGCGAACGA
TGACACGGTGCGTCCATTGTTTGGTCAACACGTAGTCCTCACAAATCCCGGTCTGCAGCAACTCTTTTTGGAAGTCAATA
ACGGTTCGGAATGGATCTGCTACTTCCCCCACCCTCTGCGCGTGGTGTGCGGCGGCATCAGTATCCCCGGCCGCTGGGAT
ACCACCCCAGACCCCGCGGTGACTGACCGAATCCTGCAACGCTGCCGAAGAATCGAACCACGGCTCGGCGAGGCCGCGGT
GATCGAGACAATTACCGGGTTGCGGCCAGACCGTCCGTCGCCGCGGGTGGAGGTTGAGCTGAGTGGGTCCGTGCGGTACA
TCCACAACTACGGCCACAGCAGCAGCGGCGTGACCTTATCGTGGGGGTGCGCACGCGACGTGGTGCGCCTTGTCAGCGAC
TGA

Upstream 100 bases:

>100_bases
CAATGGGCTGCTCGCCTCAAACGGCCAGCAAGTGCCGCGGTCCTGATCGCTACTGGCCACACCCAGACAACTGAACCGGT
TTCTCGGTTACGGTGCTGCC

Downstream 100 bases:

>100_bases
TCATTGACCCCGAGTTCTCAGTCGCAAGTGCGGCGCCCAGCACCTCGAATCAGCATCGACAGCACCCAGCTCACAATTGA
CAACACGATCGCAGCCCAGA

Product: D-amino acid oxidase

Products: NA

Alternate protein names: DAAO; DAMOX; DAO [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MASNGQQIVVIGAGVSGLTSAVCLAEAGWPVQLWAAAMPQQTTSAVAGAVWAPPRPEERASTSLAWTGHSLQIFRELAND
PSTGVRMAPALTVGDLPGANAMGLAAKLIPDLRPADLADLPDGFGAGFFGTMPMIDMPQYLDYLTARLAAAGCELETRSV
RSLAEAADTAPIIVNCTGLGAAALANDDTVRPLFGQHVVLTNPGLQQLFLEVNNGSEWICYFPHPLRVVCGGISIPGRWD
TTPDPAVTDRILQRCRRIEPRLGEAAVIETITGLRPDRPSPRVEVELSGSVRYIHNYGHSSSGVTLSWGCARDVVRLVSD

Sequences:

>Translated_320_residues
MASNGQQIVVIGAGVSGLTSAVCLAEAGWPVQLWAAAMPQQTTSAVAGAVWAPPRPEERASTSLAWTGHSLQIFRELAND
PSTGVRMAPALTVGDLPGANAMGLAAKLIPDLRPADLADLPDGFGAGFFGTMPMIDMPQYLDYLTARLAAAGCELETRSV
RSLAEAADTAPIIVNCTGLGAAALANDDTVRPLFGQHVVLTNPGLQQLFLEVNNGSEWICYFPHPLRVVCGGISIPGRWD
TTPDPAVTDRILQRCRRIEPRLGEAAVIETITGLRPDRPSPRVEVELSGSVRYIHNYGHSSSGVTLSWGCARDVVRLVSD
>Mature_319_residues
ASNGQQIVVIGAGVSGLTSAVCLAEAGWPVQLWAAAMPQQTTSAVAGAVWAPPRPEERASTSLAWTGHSLQIFRELANDP
STGVRMAPALTVGDLPGANAMGLAAKLIPDLRPADLADLPDGFGAGFFGTMPMIDMPQYLDYLTARLAAAGCELETRSVR
SLAEAADTAPIIVNCTGLGAAALANDDTVRPLFGQHVVLTNPGLQQLFLEVNNGSEWICYFPHPLRVVCGGISIPGRWDT
TPDPAVTDRILQRCRRIEPRLGEAAVIETITGLRPDRPSPRVEVELSGSVRYIHNYGHSSSGVTLSWGCARDVVRLVSD

Specific function: Unknown

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DAMOX/DASOX family [H]

Homologues:

Organism=Homo sapiens, GI148539837, Length=340, Percent_Identity=31.1764705882353, Blast_Score=138, Evalue=5e-33,
Organism=Homo sapiens, GI40217815, Length=328, Percent_Identity=30.1829268292683, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI40217827, Length=321, Percent_Identity=28.0373831775701, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71999501, Length=321, Percent_Identity=25.5451713395639, Blast_Score=120, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17559850, Length=342, Percent_Identity=26.9005847953216, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71986554, Length=332, Percent_Identity=27.1084337349398, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24652525, Length=330, Percent_Identity=27.8787878787879, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI19920852, Length=333, Percent_Identity=28.2282282282282, Blast_Score=98, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023209
- InterPro:   IPR006076
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.4.3.3 [H]

Molecular weight: Translated: 33901; Mature: 33770

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASNGQQIVVIGAGVSGLTSAVCLAEAGWPVQLWAAAMPQQTTSAVAGAVWAPPRPEERA
CCCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHCCCCCCCCCHHHC
STSLAWTGHSLQIFRELANDPSTGVRMAPALTVGDLPGANAMGLAAKLIPDLRPADLADL
CCEEEECCCHHHHHHHHHCCCCCCEEECCEEEECCCCCCCHHHHHHHHCCCCCCCCHHCC
PDGFGAGFFGTMPMIDMPQYLDYLTARLAAAGCELETRSVRSLAEAADTAPIIVNCTGLG
CCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCC
AAALANDDTVRPLFGQHVVLTNPGLQQLFLEVNNGSEWICYFPHPLRVVCGGISIPGRWD
CHHHCCCCCCCHHHCCEEEEECCCHHHEEEEECCCCEEEEECCCCHHEEECCCCCCCCCC
TTPDPAVTDRILQRCRRIEPRLGEAAVIETITGLRPDRPSPRVEVELSGSVRYIHNYGHS
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCEEEEEECCCC
SSGVTLSWGCARDVVRLVSD
CCCEEEECHHHHHHHHHHCC
>Mature Secondary Structure 
ASNGQQIVVIGAGVSGLTSAVCLAEAGWPVQLWAAAMPQQTTSAVAGAVWAPPRPEERA
CCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHCCCCCCCCCHHHC
STSLAWTGHSLQIFRELANDPSTGVRMAPALTVGDLPGANAMGLAAKLIPDLRPADLADL
CCEEEECCCHHHHHHHHHCCCCCCEEECCEEEECCCCCCCHHHHHHHHCCCCCCCCHHCC
PDGFGAGFFGTMPMIDMPQYLDYLTARLAAAGCELETRSVRSLAEAADTAPIIVNCTGLG
CCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCC
AAALANDDTVRPLFGQHVVLTNPGLQQLFLEVNNGSEWICYFPHPLRVVCGGISIPGRWD
CHHHCCCCCCCHHHCCEEEEECCCHHHEEEEECCCCEEEEECCCCHHEEECCCCCCCCCC
TTPDPAVTDRILQRCRRIEPRLGEAAVIETITGLRPDRPSPRVEVELSGSVRYIHNYGHS
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCEEEEEECCCC
SSGVTLSWGCARDVVRLVSD
CCCEEEECHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]