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The map label for this gene is glpX [H]

Identifier: 221230526

GI number: 221230526

Start: 2332554

End: 2333540

Strand: Direct

Name: glpX [H]

Synonym: MLBr_01946

Alternate gene names: 221230526

Gene position: 2332554-2333540 (Clockwise)

Preceding gene: 221230524

Following gene: 221230527

Centisome position: 71.37

GC content: 63.12

Gene sequence:

>987_bases
ATGGAACTTGTCCGGGTTACCGAAGCCGGTGCCATGGCCGCCGGCCGGTGGGTGGGCCGCGGCAACAAGGAGGGCGGTGA
CGGCGCGGCCGTCGATACGATACGGGAACTGGTGAACACAGTCTCGATGCGCGGTGTCGTTGTCATCGGCGAAGGCGAGA
AAGACCATGCGCCGATGCTGTACAACGGCGAGGAAGTCGGCAACGGTGACGGCCCAGACTGCGACTTTGCAGTCGATCCG
ATTGACGGCACCACGCTGATGAGCAAAGGCATGCCCAACGCCATCTCGGTGCTGGCGGTCGCCGATCGGGGCGCGATGTT
CGACCCTTCGGCAGTGTTTTACATGAACAAGATCACCGTTGGTCCTGACGCCGCGCACGTCCTAGACATCACCGCGCCGA
TCGGCGAGAACATCCGGGCGGTCGCCAAGGTCAAAGACTTATCAGTGCGGGACATGACCGTGTGCATACTGGATCGGCCA
CGACACGCCCAGTTGATCGACGACGTCCGCGCCACCGGCGCCAGGATCCGGCTAATCACCGACGGCGACGTCGCCGGCGC
AATCTCCGCGTGCCGCCCCCAATCGGGCACCGACATGTTGGCTGGTATCGGCGGCACCCCGGAAGGCATCATCGCAGCCG
CGGCGATCCGGTGCATGGGCGGGGCGATCCAAGCTCAACTAGCGCCACGCGATGACGTCGAACGCCGCAAGGCTCTCGAC
GCCGGCTACAACCTAGACCGGATTTTGACTACCGAAGATCTGGTTTCCGGAGAAAACGTCTTCTTCTGCGCCACTGGGGT
CACCGACGGCGATCTGCTCAAGGGGGTGCGCTACTACGCTGGCGGCTGCACCACCCAGTCAATCGTGATGCGTTCGAAGT
CGGGCACCGTTCGGATGATCGAGGCCTACCACCGGCTCTCTAAACTCAACGAATACTCCGCCATCGACTTCACCGGCGAT
AACAACGCCGCCTACCCCCTGCCGTAA

Upstream 100 bases:

>100_bases
TCTGGGACAATCATTAACCATGACAGCTGAGGGCGACGGCTCGTTCAAACCCGGTCCGCCGACGGAGCGGCGTGGTGAAG
CGCCAGACCGCAACCTGGCC

Downstream 100 bases:

>100_bases
ACCACGCAATGAAGAGGACCCAATTCATGGCCGACAGCGCCGAATACCGCATCGAGCACGACACCATGGGCGAAGTCCGG
GTACCGGCAATAGCATTGTG

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MELVRVTEAGAMAAGRWVGRGNKEGGDGAAVDTIRELVNTVSMRGVVVIGEGEKDHAPMLYNGEEVGNGDGPDCDFAVDP
IDGTTLMSKGMPNAISVLAVADRGAMFDPSAVFYMNKITVGPDAAHVLDITAPIGENIRAVAKVKDLSVRDMTVCILDRP
RHAQLIDDVRATGARIRLITDGDVAGAISACRPQSGTDMLAGIGGTPEGIIAAAAIRCMGGAIQAQLAPRDDVERRKALD
AGYNLDRILTTEDLVSGENVFFCATGVTDGDLLKGVRYYAGGCTTQSIVMRSKSGTVRMIEAYHRLSKLNEYSAIDFTGD
NNAAYPLP

Sequences:

>Translated_328_residues
MELVRVTEAGAMAAGRWVGRGNKEGGDGAAVDTIRELVNTVSMRGVVVIGEGEKDHAPMLYNGEEVGNGDGPDCDFAVDP
IDGTTLMSKGMPNAISVLAVADRGAMFDPSAVFYMNKITVGPDAAHVLDITAPIGENIRAVAKVKDLSVRDMTVCILDRP
RHAQLIDDVRATGARIRLITDGDVAGAISACRPQSGTDMLAGIGGTPEGIIAAAAIRCMGGAIQAQLAPRDDVERRKALD
AGYNLDRILTTEDLVSGENVFFCATGVTDGDLLKGVRYYAGGCTTQSIVMRSKSGTVRMIEAYHRLSKLNEYSAIDFTGD
NNAAYPLP
>Mature_328_residues
MELVRVTEAGAMAAGRWVGRGNKEGGDGAAVDTIRELVNTVSMRGVVVIGEGEKDHAPMLYNGEEVGNGDGPDCDFAVDP
IDGTTLMSKGMPNAISVLAVADRGAMFDPSAVFYMNKITVGPDAAHVLDITAPIGENIRAVAKVKDLSVRDMTVCILDRP
RHAQLIDDVRATGARIRLITDGDVAGAISACRPQSGTDMLAGIGGTPEGIIAAAAIRCMGGAIQAQLAPRDDVERRKALD
AGYNLDRILTTEDLVSGENVFFCATGVTDGDLLKGVRYYAGGCTTQSIVMRSKSGTVRMIEAYHRLSKLNEYSAIDFTGD
NNAAYPLP

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=323, Percent_Identity=41.7956656346749, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1789298, Length=315, Percent_Identity=38.7301587301587, Blast_Score=221, Evalue=4e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 34593; Mature: 34593

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELVRVTEAGAMAAGRWVGRGNKEGGDGAAVDTIRELVNTVSMRGVVVIGEGEKDHAPML
CCEEEEECCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEE
YNGEEVGNGDGPDCDFAVDPIDGTTLMSKGMPNAISVLAVADRGAMFDPSAVFYMNKITV
ECCCCCCCCCCCCCCEEECCCCCCHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEEEEEE
GPDAAHVLDITAPIGENIRAVAKVKDLSVRDMTVCILDRPRHAQLIDDVRATGARIRLIT
CCCCEEEEEEECCCCCCCEEEHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEE
DGDVAGAISACRPQSGTDMLAGIGGTPEGIIAAAAIRCMGGAIQAQLAPRDDVERRKALD
CCCCHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHH
AGYNLDRILTTEDLVSGENVFFCATGVTDGDLLKGVRYYAGGCTTQSIVMRSKSGTVRMI
CCCCCCEEEEHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHEEEECCCCCCHHH
EAYHRLSKLNEYSAIDFTGDNNAAYPLP
HHHHHHHHCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MELVRVTEAGAMAAGRWVGRGNKEGGDGAAVDTIRELVNTVSMRGVVVIGEGEKDHAPML
CCEEEEECCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEE
YNGEEVGNGDGPDCDFAVDPIDGTTLMSKGMPNAISVLAVADRGAMFDPSAVFYMNKITV
ECCCCCCCCCCCCCCEEECCCCCCHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEEEEEE
GPDAAHVLDITAPIGENIRAVAKVKDLSVRDMTVCILDRPRHAQLIDDVRATGARIRLIT
CCCCEEEEEEECCCCCCCEEEHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEE
DGDVAGAISACRPQSGTDMLAGIGGTPEGIIAAAAIRCMGGAIQAQLAPRDDVERRKALD
CCCCHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHH
AGYNLDRILTTEDLVSGENVFFCATGVTDGDLLKGVRYYAGGCTTQSIVMRSKSGTVRMI
CCCCCCEEEEHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHEEEECCCCCCHHH
EAYHRLSKLNEYSAIDFTGDNNAAYPLP
HHHHHHHHCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]