Click here to switch to the map view.

The map label for this gene is argK [C]

Identifier: 221230434

GI number: 221230434

Start: 2176846

End: 2177829

Strand: Reverse

Name: argK [C]

Synonym: MLBr_01798

Alternate gene names: 221230434

Gene position: 2177829-2176846 (Counterclockwise)

Preceding gene: 221230435

Following gene: 221230429

Centisome position: 66.64

GC content: 60.57

Gene sequence:

>984_bases
ATGGCGGGGGACAGCACCGTGGACAGACTAGTCGCTGCTGTCCGTAGTGGTGATCGCGTGGCATTGCCGCGGGCTATAAC
GTTGGTGGAGTCCACTCGCTCCGACCATCGTGAGCAGGCGCAGCAGCTGCTGCTGGCATTGCAACCGGATGCTGGAAACG
CCCATCGGGTGGGCATCACCGGGGTGCCCGGGGTAGGAAAGTCCACCGCCATTGAGGCGCTTGGCATGCATCTGATCGAA
CGGGGTCATCGAGTGGCGGTGCTGGCCGTCGACCCATCATCGGTCCGTACCGGTGGATCCATCCTTGGCGACAAGACCCG
GATGGCGCGGCTAGCGGTACACCCGGACGCCTATATCCGGCCATCGCCGACATCGGGCACGTTGGGCGGGGTGACGAAGG
CCACTCGGGAAACAGTTGTCCTGTTGGAGGCGGCTGGTTTTGATGTAATTCTGATCGAAACTGTAGGCGTCGGACAGTCT
GAGGTAGCGGTGGCTAATATGGTCGACACCTTCGTTTTGTTGGCCTTGGCGCGTACCGGCGATCAGTTGCAGGGCATCAA
AAAAGGCGTGCTGGAGCTGGCCGACATCGTGGTGGTGAACAAGGCCGATGGGGAGCATCTGCGCGATGCTCGGCTAGCTG
CTCGGGACCTGTCATCGGCACTCCGATTGATCTATACACACGAAAAAATTTGGAGACCAAAAGTTTTCACGATTAGTGCG
ACTGAGGGGACCGGTCTGACCCAGATGTGGGAAGCGGTCGAATGTCATCGTCAAGTGCTTACTGCCTCCGGCGAGTTTGA
GAACCGTCGACTGGCCCAGCAAGTCGAGTGGGCTTGGCAGATGGTCCGTGACGCGGTGCTAGACCGGGTGCTGTCCAACC
CCGCGGTGCGTGAGATTCGTGCTGAGCTGGAGTGTCAGGTGCGAGCAGGGGAGCTGACTCCCGCGATGGCGGCCCAGCAA
ATCCTGCAGGCAGCATCCTGCTAA

Upstream 100 bases:

>100_bases
CGGGGCTACTGCCATCTTCCCTCCTGGGACGGTGATAGCCTACGCCGCAATTGGCTTGCTGCATAAGCTCGCCGGCCGGC
TGGGGTACACTCTCACCTAG

Downstream 100 bases:

>100_bases
TGGAAAGGTAAGTTAATTATCGTTTGCTCATGACTGATGTGCAATCATCGTAAATTCACGAAGTGTGAAGGTGTAAGCTC
AAGTCGATCGCCGTGTGTAC

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MAGDSTVDRLVAAVRSGDRVALPRAITLVESTRSDHREQAQQLLLALQPDAGNAHRVGITGVPGVGKSTAIEALGMHLIE
RGHRVAVLAVDPSSVRTGGSILGDKTRMARLAVHPDAYIRPSPTSGTLGGVTKATRETVVLLEAAGFDVILIETVGVGQS
EVAVANMVDTFVLLALARTGDQLQGIKKGVLELADIVVVNKADGEHLRDARLAARDLSSALRLIYTHEKIWRPKVFTISA
TEGTGLTQMWEAVECHRQVLTASGEFENRRLAQQVEWAWQMVRDAVLDRVLSNPAVREIRAELECQVRAGELTPAMAAQQ
ILQAASC

Sequences:

>Translated_327_residues
MAGDSTVDRLVAAVRSGDRVALPRAITLVESTRSDHREQAQQLLLALQPDAGNAHRVGITGVPGVGKSTAIEALGMHLIE
RGHRVAVLAVDPSSVRTGGSILGDKTRMARLAVHPDAYIRPSPTSGTLGGVTKATRETVVLLEAAGFDVILIETVGVGQS
EVAVANMVDTFVLLALARTGDQLQGIKKGVLELADIVVVNKADGEHLRDARLAARDLSSALRLIYTHEKIWRPKVFTISA
TEGTGLTQMWEAVECHRQVLTASGEFENRRLAQQVEWAWQMVRDAVLDRVLSNPAVREIRAELECQVRAGELTPAMAAQQ
ILQAASC
>Mature_326_residues
AGDSTVDRLVAAVRSGDRVALPRAITLVESTRSDHREQAQQLLLALQPDAGNAHRVGITGVPGVGKSTAIEALGMHLIER
GHRVAVLAVDPSSVRTGGSILGDKTRMARLAVHPDAYIRPSPTSGTLGGVTKATRETVVLLEAAGFDVILIETVGVGQSE
VAVANMVDTFVLLALARTGDQLQGIKKGVLELADIVVVNKADGEHLRDARLAARDLSSALRLIYTHEKIWRPKVFTISAT
EGTGLTQMWEAVECHRQVLTASGEFENRRLAQQVEWAWQMVRDAVLDRVLSNPAVREIRAELECQVRAGELTPAMAAQQI
LQAASC

Specific function: Probable GTPase. May also bind and hydrolyze ATP. May function as chaperone (Probable) [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=328, Percent_Identity=49.390243902439, Blast_Score=308, Evalue=3e-84,
Organism=Escherichia coli, GI1789285, Length=321, Percent_Identity=44.8598130841121, Blast_Score=272, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI71994271, Length=331, Percent_Identity=41.3897280966767, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71994275, Length=270, Percent_Identity=43.7037037037037, Blast_Score=245, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 35133; Mature: 35002

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGDSTVDRLVAAVRSGDRVALPRAITLVESTRSDHREQAQQLLLALQPDAGNAHRVGIT
CCCCHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEC
GVPGVGKSTAIEALGMHLIERGHRVAVLAVDPSSVRTGGSILGDKTRMARLAVHPDAYIR
CCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHCCHHHHEEEEECCCCCCC
PSPTSGTLGGVTKATRETVVLLEAAGFDVILIETVGVGQSEVAVANMVDTFVLLALARTG
CCCCCCCCCCHHHHCCCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCC
DQLQGIKKGVLELADIVVVNKADGEHLRDARLAARDLSSALRLIYTHEKIWRPKVFTISA
HHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
TEGTGLTQMWEAVECHRQVLTASGEFENRRLAQQVEWAWQMVRDAVLDRVLSNPAVREIR
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AELECQVRAGELTPAMAAQQILQAASC
HHHHEEEECCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
AGDSTVDRLVAAVRSGDRVALPRAITLVESTRSDHREQAQQLLLALQPDAGNAHRVGIT
CCCHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEC
GVPGVGKSTAIEALGMHLIERGHRVAVLAVDPSSVRTGGSILGDKTRMARLAVHPDAYIR
CCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHCCHHHHEEEEECCCCCCC
PSPTSGTLGGVTKATRETVVLLEAAGFDVILIETVGVGQSEVAVANMVDTFVLLALARTG
CCCCCCCCCCHHHHCCCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCC
DQLQGIKKGVLELADIVVVNKADGEHLRDARLAARDLSSALRLIYTHEKIWRPKVFTISA
HHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
TEGTGLTQMWEAVECHRQVLTASGEFENRRLAQQVEWAWQMVRDAVLDRVLSNPAVREIR
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AELECQVRAGELTPAMAAQQILQAASC
HHHHEEEECCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]