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The map label for this gene is coaD [H]

Identifier: 221230357

GI number: 221230357

Start: 2005059

End: 2005532

Strand: Reverse

Name: coaD [H]

Synonym: MLBr_01663

Alternate gene names: 221230357

Gene position: 2005532-2005059 (Counterclockwise)

Preceding gene: 221230358

Following gene: 221230356

Centisome position: 61.37

GC content: 57.59

Gene sequence:

>474_bases
GTGGTATGTCCGGGGTCATTCGATCCGGTGACGTTGGGCCACATCGACGTTTTTGAACGCGCTGCGGCTCAGTTCGACGA
GGTGGTGGTCGCGATCCTGATCAACCCCGTCAAGAAGGGCATGTTCGACCTCGACGAGCGGATAGCGATGATCAATGAGT
CGACGATGCACCTGCCTAACTTGCGTGTGGAGGCCGGAGAGGGATTGGTGGTCGCCTTAGTCAGGTCCCGTGGGATGACA
GCCATCGTGAAGGGCCTGCGCACCGGCGTGGATTTCGAATACGAGCTGCAGATGGCGCAGATGAACAAACACATCGCAGG
CGTCGACACTTTCTTCGTCGCAACGGCGCCGCGGTATTCGTTCGTATCGTCGTCGTTGGTCAAAGAGGTTGCTATGCTAG
GCGGCGACGTTTCAGAGCTATTGCCGGAATCGGTGAACCGCCGATTCCGGGAAAAGATGTCCGGCACTAGTTAA

Upstream 100 bases:

>100_bases
GCCGGATGGAGTTCGTGGCAGTCGCGTGGGTACGGTGACACCCGTTTGGAGCTTGCCGAACTGACCTGATCCGCCGTGTA
GCGTTTCGATCATGAGCAGT

Downstream 100 bases:

>100_bases
GGCCGCGGTCAAAAAACTAGGTTTGGGTTATTGCTGTTTTTTGGTGCCACTGAACGTGGCACCAAAAAAGTCGAACCCCT
CACTTATGTGTACTGTTTGG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MVCPGSFDPVTLGHIDVFERAAAQFDEVVVAILINPVKKGMFDLDERIAMINESTMHLPNLRVEAGEGLVVALVRSRGMT
AIVKGLRTGVDFEYELQMAQMNKHIAGVDTFFVATAPRYSFVSSSLVKEVAMLGGDVSELLPESVNRRFREKMSGTS

Sequences:

>Translated_157_residues
MVCPGSFDPVTLGHIDVFERAAAQFDEVVVAILINPVKKGMFDLDERIAMINESTMHLPNLRVEAGEGLVVALVRSRGMT
AIVKGLRTGVDFEYELQMAQMNKHIAGVDTFFVATAPRYSFVSSSLVKEVAMLGGDVSELLPESVNRRFREKMSGTS
>Mature_157_residues
MVCPGSFDPVTLGHIDVFERAAAQFDEVVVAILINPVKKGMFDLDERIAMINESTMHLPNLRVEAGEGLVVALVRSRGMT
AIVKGLRTGVDFEYELQMAQMNKHIAGVDTFFVATAPRYSFVSSSLVKEVAMLGGDVSELLPESVNRRFREKMSGTS

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=154, Percent_Identity=43.5064935064935, Blast_Score=144, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 17223; Mature: 17223

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVCPGSFDPVTLGHIDVFERAAAQFDEVVVAILINPVKKGMFDLDERIAMINESTMHLPN
CCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LRVEAGEGLVVALVRSRGMTAIVKGLRTGVDFEYELQMAQMNKHIAGVDTFFVATAPRYS
CEEECCCCEEEEEHHHCCHHHHHHHHHHCCCCCEEHHHHHHHHHHCCHHHHEEECCCCHH
FVSSSLVKEVAMLGGDVSELLPESVNRRFREKMSGTS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVCPGSFDPVTLGHIDVFERAAAQFDEVVVAILINPVKKGMFDLDERIAMINESTMHLPN
CCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LRVEAGEGLVVALVRSRGMTAIVKGLRTGVDFEYELQMAQMNKHIAGVDTFFVATAPRYS
CEEECCCCEEEEEHHHCCHHHHHHHHHHCCCCCEEHHHHHHHHHHCCHHHHEEECCCCHH
FVSSSLVKEVAMLGGDVSELLPESVNRRFREKMSGTS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]