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The map label for this gene is yaeL [C]

Identifier: 221230307

GI number: 221230307

Start: 1906917

End: 1908131

Strand: Reverse

Name: yaeL [C]

Synonym: MLBr_01582

Alternate gene names: 221230307

Gene position: 1908131-1906917 (Counterclockwise)

Preceding gene: 221230308

Following gene: 221230306

Centisome position: 58.39

GC content: 58.68

Gene sequence:

>1215_bases
ATGATGTTCGCTCTCGGCATTGTGCTGTTCGCTATCGCCATTCTTATTTCGGTGGCCCTGCACGAATGTGGCCACTTGTG
GGTGGCGTGCGCCACTGGCATGAAGGTGCGTCGTTATTTTGTTGGTTTCGGCCCCACCCTCTGGTCGACCCGGCGCGGTG
AAACCCAATATGGTATCAAGGCCGTTCCGCTAGGCGGTTTTTGTGATATCGTCGGTATGACCTCGGTTGAGAAGCTGGAG
CCTGACGAATCTGACCGAGCAATGTACAAACAAGCGACCTGGAAGCGGGTGGCGGTACTGTTCGCCGGACCTGCTATGAA
CTTTGTGATCTGCCTGGTGCTGATCTATGGCATCGCGCTGGTCTGGGGGCTACCCAACCTGCACATGCCTACCAGGGCTG
TAATCGGTGAAACTGCTTGTGTAGCATCGGAACTGGACCAGGGCAAGCTCGGAAACTGCACTGGCCCAGGTCCGGCGGCG
CTGGCCGGACTCCGTGCTGGCGACGTCGTCGTCAAGATCGGTGATACTACGGTGTCGACCTTCGATGACATGGCCGCTGT
GGTGCGTAAGTTGCATGGTACGGTGCCGATTGTCTTCGAACGGGACGGCACTGCGATTACTAGCTACGTCGACATCACGC
CTACCCAGCGCTATATGTCCAAAGGAAAGGGTAGTCAACTCGAACCAGCCACGGTCGGTGCCATTGGAGTCGGCGCACAC
CATCTGCTGCCCACGCATTACGGCGTATTCTCCGCTTTGCCCGCCACCGCCGCTTTCGCCGGGGATTTGACCGTCGAGGT
GGGCAAGGCTCTGGTCACCATACCGACCAAGCTGGGTGCCTTGGTGCACGCTATCGGTGGTGGACAGCGTGACCCGCAGA
CGCCGATGAGTGTGGTCGGCGCCAGCATCATCGGCGGCGACACCGTCGATCATGGGCTGTGGGTGGCGTTCTGGTTTTTC
TTGGCGCAGCTGAACCTTATTCTGGGTGCCATCAACCTGGTGCCGTTGCTGCCTTTCGATGGCGGCCACATCGCCATTGC
CGTATTCGAGAGGATCCGTAACCTCATCCGGTCCGCACGTGGCGTGGTCGTGGCCGCGCCGGTGAACTATCTCAAGCTCA
TGCCCGCGACCTATGTGGTCTTGGTCTTTGTAGTCGGGTATGTGCTGTTGACCGTGACCGCCGATCTGGTAAACCCAATC
AGGCTTTTTCAATAG

Upstream 100 bases:

>100_bases
ACGCGCAGCGCTGGGCCCGTGAGCGAGCGTTGTGTGCGGTAGCAACAGCGAGTTCTGGAAAGGTCTCTGACATGGTCTTA
GAAAGGTCCTAAAAGGCTCG

Downstream 100 bases:

>100_bases
CCAATAGTGAAAAACGAGAAAGCCAATAGTGAAAACCGAGAAATGGGGAACAGTGAACATGCGTCTGGGCATGCCCGAGG
CTCCGGCTCCCGGGCTTGCC

Product: putative integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MMFALGIVLFAIAILISVALHECGHLWVACATGMKVRRYFVGFGPTLWSTRRGETQYGIKAVPLGGFCDIVGMTSVEKLE
PDESDRAMYKQATWKRVAVLFAGPAMNFVICLVLIYGIALVWGLPNLHMPTRAVIGETACVASELDQGKLGNCTGPGPAA
LAGLRAGDVVVKIGDTTVSTFDDMAAVVRKLHGTVPIVFERDGTAITSYVDITPTQRYMSKGKGSQLEPATVGAIGVGAH
HLLPTHYGVFSALPATAAFAGDLTVEVGKALVTIPTKLGALVHAIGGGQRDPQTPMSVVGASIIGGDTVDHGLWVAFWFF
LAQLNLILGAINLVPLLPFDGGHIAIAVFERIRNLIRSARGVVVAAPVNYLKLMPATYVVLVFVVGYVLLTVTADLVNPI
RLFQ

Sequences:

>Translated_404_residues
MMFALGIVLFAIAILISVALHECGHLWVACATGMKVRRYFVGFGPTLWSTRRGETQYGIKAVPLGGFCDIVGMTSVEKLE
PDESDRAMYKQATWKRVAVLFAGPAMNFVICLVLIYGIALVWGLPNLHMPTRAVIGETACVASELDQGKLGNCTGPGPAA
LAGLRAGDVVVKIGDTTVSTFDDMAAVVRKLHGTVPIVFERDGTAITSYVDITPTQRYMSKGKGSQLEPATVGAIGVGAH
HLLPTHYGVFSALPATAAFAGDLTVEVGKALVTIPTKLGALVHAIGGGQRDPQTPMSVVGASIIGGDTVDHGLWVAFWFF
LAQLNLILGAINLVPLLPFDGGHIAIAVFERIRNLIRSARGVVVAAPVNYLKLMPATYVVLVFVVGYVLLTVTADLVNPI
RLFQ
>Mature_404_residues
MMFALGIVLFAIAILISVALHECGHLWVACATGMKVRRYFVGFGPTLWSTRRGETQYGIKAVPLGGFCDIVGMTSVEKLE
PDESDRAMYKQATWKRVAVLFAGPAMNFVICLVLIYGIALVWGLPNLHMPTRAVIGETACVASELDQGKLGNCTGPGPAA
LAGLRAGDVVVKIGDTTVSTFDDMAAVVRKLHGTVPIVFERDGTAITSYVDITPTQRYMSKGKGSQLEPATVGAIGVGAH
HLLPTHYGVFSALPATAAFAGDLTVEVGKALVTIPTKLGALVHAIGGGQRDPQTPMSVVGASIIGGDTVDHGLWVAFWFF
LAQLNLILGAINLVPLLPFDGGHIAIAVFERIRNLIRSARGVVVAAPVNYLKLMPATYVVLVFVVGYVLLTVTADLVNPI
RLFQ

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain

Homologues:

Organism=Escherichia coli, GI1786373, Length=247, Percent_Identity=29.1497975708502, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1582_MYCLE (Q9CBU4)

Other databases:

- EMBL:   AL583922
- PIR:   H87106
- RefSeq:   NP_302093.1
- ProteinModelPortal:   Q9CBU4
- SMR:   Q9CBU4
- MEROPS:   M50.005
- EnsemblBacteria:   EBMYCT00000028367
- GeneID:   909642
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML1582
- NMPDR:   fig|272631.1.peg.965
- Leproma:   ML1582
- GeneTree:   EBGT00050000017531
- HOGENOM:   HBG664087
- OMA:   GETEYGL
- ProtClustDB:   CLSK872116
- BioCyc:   MLEP272631:ML1582-MONOMER
- GO:   GO:0006508
- InterPro:   IPR001478
- InterPro:   IPR008915
- SMART:   SM00228

Pfam domain/function: PF02163 Peptidase_M50; SSF50156 PDZ

EC number: NA

Molecular weight: Translated: 42876; Mature: 42876

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS50106 PDZ; PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 22-22

Signals:

None

Transmembrane regions:

HASH(0x2a1356a8)-; HASH(0x29e1c28c)-; HASH(0x29e123a4)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFALGIVLFAIAILISVALHECGHLWVACATGMKVRRYFVGFGPTLWSTRRGETQYGIK
CHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHCCHHHHHHHHCCCCHHCCCCCCCCCCCEE
AVPLGGFCDIVGMTSVEKLEPDESDRAMYKQATWKRVAVLFAGPAMNFVICLVLIYGIAL
EECCCCHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHEEEEEECHHHHHHHHHHHHHHHHH
VWGLPNLHMPTRAVIGETACVASELDQGKLGNCTGPGPAALAGLRAGDVVVKIGDTTVST
HHCCCCCCCCHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCHHHH
FDDMAAVVRKLHGTVPIVFERDGTAITSYVDITPTQRYMSKGKGSQLEPATVGAIGVGAH
HHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCCHHHHHHCCCCCCCCCCCCCEECCCHH
HLLPTHYGVFSALPATAAFAGDLTVEVGKALVTIPTKLGALVHAIGGGQRDPQTPMSVVG
HHCCHHHHHHHHHHHHHHHCCCCHHHHCCEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHH
ASIIGGDTVDHGLWVAFWFFLAQLNLILGAINLVPLLPFDGGHIAIAVFERIRNLIRSAR
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHC
GVVVAAPVNYLKLMPATYVVLVFVVGYVLLTVTADLVNPIRLFQ
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MMFALGIVLFAIAILISVALHECGHLWVACATGMKVRRYFVGFGPTLWSTRRGETQYGIK
CHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHCCHHHHHHHHCCCCHHCCCCCCCCCCCEE
AVPLGGFCDIVGMTSVEKLEPDESDRAMYKQATWKRVAVLFAGPAMNFVICLVLIYGIAL
EECCCCHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHEEEEEECHHHHHHHHHHHHHHHHH
VWGLPNLHMPTRAVIGETACVASELDQGKLGNCTGPGPAALAGLRAGDVVVKIGDTTVST
HHCCCCCCCCHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCHHHH
FDDMAAVVRKLHGTVPIVFERDGTAITSYVDITPTQRYMSKGKGSQLEPATVGAIGVGAH
HHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCCHHHHHHCCCCCCCCCCCCCEECCCHH
HLLPTHYGVFSALPATAAFAGDLTVEVGKALVTIPTKLGALVHAIGGGQRDPQTPMSVVG
HHCCHHHHHHHHHHHHHHHCCCCHHHHCCEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHH
ASIIGGDTVDHGLWVAFWFFLAQLNLILGAINLVPLLPFDGGHIAIAVFERIRNLIRSAR
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHC
GVVVAAPVNYLKLMPATYVVLVFVVGYVLLTVTADLVNPIRLFQ
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002