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The map label for this gene is eccA5 [H]

Identifier: 221230283

GI number: 221230283

Start: 1851655

End: 1853487

Strand: Reverse

Name: eccA5 [H]

Synonym: MLBr_01536

Alternate gene names: 221230283

Gene position: 1853487-1851655 (Counterclockwise)

Preceding gene: 221230284

Following gene: 221230281

Centisome position: 56.72

GC content: 57.39

Gene sequence:

>1833_bases
ATGACGCGCCCACAGTCAACCGCCGAAGACGCCCGCAACGCTATGGTTGCCGGCCTGCTGGCATCAGGGATCTCTGTCAA
CGGACTGCAGCCCAGCCACAACCCACAAGTTGCGTCGCAAATGTTCAGGACGGCCACCACGCTTGATCCAGGGATGTGTG
ACGCCTGGCAGGCGCGAATACTGGCAGGTGATCAGAGCATCGAAGTGCTGGCTGGCGCATGGAGTTCAATCAGGACATTC
GGTTGGGAGACGCGTCGCCTTGGGGTCACCGATTTGCAGTTTCGTCCAGAAGTGTCCGACGGGTTGTTTCTACGACTAGC
GGTAACCAGTGTGGAGTCGTTAGCTTGCGCTTATGCCGCCGTGCTGGTCAAGGCGAAACGTTACGCGGAAGCGGCCAAAC
TGCTTGAGAGTGTCGAGCCACGGCATCCTTTCGACACCGAGCTGGTCAACTATGTGCGGGGTATGCTGTACTTCCGAACC
AAACGTTGGCCGGATGTGCTTACCCAATTCCCTGAGGGAAAGCAATGGCGTCACCCCGACCTGAAGGCCGCGGGCGCGGC
AATGGCTACTTCTGCGCTGGCATCGCTTGGGGTTTTTGAAGAGGCGTTCCGGCGTGGCAAGGAAGCAATCGAGGGTGACC
GCGTGCCCCGCGCGGCCAATATCGCTTTGTACACCCAAGGCATGTGCTTACGACATGTTGGTCGAGAAGACGAGGCCGTC
GAGCTGTTGCGTCGGGTGTATTCGCGGGACGCAAAGTTTACCCCGGCTCGAGAGGCATTGGATAATAACAACTTTCGTCT
GACACTGACTGATCCGGAAACAATTGAGGCGCGCACTGATCCGTGGGATCCGGACAGTGCCCCGACCCGTGCGCAGACCG
AGGCCGCTCGCTACGCGAGGATAGCCGCAAAGTATTTGGCGGAAGGCGATGCCGAACTCAACGCGATGCTGGGCATGGAA
CAAGCCAAGCGAGAAATCAAACTCATCAAGTCGACAACAAGGGTGAACTTGGCCCGTGCCAAAATGGGTTTGCCGGTACC
GGTGACATCGCGCCACACCTTGTTGCTTGGACCACCGGGTACCGGGAAGACTTCGGTAGCACGTGCTTTCACCAAGCAGC
TGTGTGGGTTGACTGTGCTGCGCAAGCCACTTGTAGTCGAGACAAGCCGCACCAAGCTGTTAGGCCGGCATATGGCTGAT
GCGGAGAAAAACACCGAGGAGATGCTCGAGGGTGCGTTGGGTGGGGCGGTCTTCTTCGATGAAATGCACACCCTACATGA
GAAGGGCTATACCCGAGGAGACCCCTACGGTAATGCGATTATCAACACGCTGCTGCTGTATATGGAGAACCATCGCGACG
AGCTGGTGGTGTTCGGTGCGGGCTACGCCAAGGCGATGGATAAAATGCTCGAGGTGAATCAGGGTCTGCGACGGCGGTTT
TCGACGGTGATCGAGTTTTTCAGTTACACCCCTGAGGAGTTGATCGCGCTGACCCAATTGATGGGCCAGGAGAATGAAGA
CGTCATCACTGAGCAAGAGGCACAGGTGTTGTTGCCGTCGTACACAAAATTCTACCTTGACGAGACCTATTCTGAAGATG
GAGATCTAATTCGTGGTATCGACATGCTCGGTAATGCCGGCTTTGTGCGCAATGTAGTGGAGAAGGCCCGCGACCACCGT
AGCTTCCGCCTGGACGACGAGGACCTCGATGCGGTACTGGCCAGTGACCTCACCCAATTCAGCGCTGAACAGCTGTTACG
CTTCAAGGAGTTGACCAGTGCCGACCTGACCGAAGGCCTCAGCGCGGCGGTGGCTGAGAGAAAGTCGTCATAG

Upstream 100 bases:

>100_bases
CCGTATTGGTCGTGCCTAGCCGAGAGTTAAGCGACCATGATGAGCTGGTGCTGCCGGTGGGACAGGGGCGGGAAGGCTCA
GCGAGCTTGTTTGCAGGGCA

Downstream 100 bases:

>100_bases
CCGGTGGGCAATTCAGCAGCGTCCTTTGTTAACTGAGCAATCACGTGTACTTGAGCCGGCTCCAGCTGAACATCTCGCTG
GACTTCGTATCCTGGCACTA

Product: hypothetical protein

Products: NA

Alternate protein names: ESX conserved component A5; Type VII secretion system protein EccA5; T7SS protein EccA5 [H]

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MTRPQSTAEDARNAMVAGLLASGISVNGLQPSHNPQVASQMFRTATTLDPGMCDAWQARILAGDQSIEVLAGAWSSIRTF
GWETRRLGVTDLQFRPEVSDGLFLRLAVTSVESLACAYAAVLVKAKRYAEAAKLLESVEPRHPFDTELVNYVRGMLYFRT
KRWPDVLTQFPEGKQWRHPDLKAAGAAMATSALASLGVFEEAFRRGKEAIEGDRVPRAANIALYTQGMCLRHVGREDEAV
ELLRRVYSRDAKFTPAREALDNNNFRLTLTDPETIEARTDPWDPDSAPTRAQTEAARYARIAAKYLAEGDAELNAMLGME
QAKREIKLIKSTTRVNLARAKMGLPVPVTSRHTLLLGPPGTGKTSVARAFTKQLCGLTVLRKPLVVETSRTKLLGRHMAD
AEKNTEEMLEGALGGAVFFDEMHTLHEKGYTRGDPYGNAIINTLLLYMENHRDELVVFGAGYAKAMDKMLEVNQGLRRRF
STVIEFFSYTPEELIALTQLMGQENEDVITEQEAQVLLPSYTKFYLDETYSEDGDLIRGIDMLGNAGFVRNVVEKARDHR
SFRLDDEDLDAVLASDLTQFSAEQLLRFKELTSADLTEGLSAAVAERKSS

Sequences:

>Translated_610_residues
MTRPQSTAEDARNAMVAGLLASGISVNGLQPSHNPQVASQMFRTATTLDPGMCDAWQARILAGDQSIEVLAGAWSSIRTF
GWETRRLGVTDLQFRPEVSDGLFLRLAVTSVESLACAYAAVLVKAKRYAEAAKLLESVEPRHPFDTELVNYVRGMLYFRT
KRWPDVLTQFPEGKQWRHPDLKAAGAAMATSALASLGVFEEAFRRGKEAIEGDRVPRAANIALYTQGMCLRHVGREDEAV
ELLRRVYSRDAKFTPAREALDNNNFRLTLTDPETIEARTDPWDPDSAPTRAQTEAARYARIAAKYLAEGDAELNAMLGME
QAKREIKLIKSTTRVNLARAKMGLPVPVTSRHTLLLGPPGTGKTSVARAFTKQLCGLTVLRKPLVVETSRTKLLGRHMAD
AEKNTEEMLEGALGGAVFFDEMHTLHEKGYTRGDPYGNAIINTLLLYMENHRDELVVFGAGYAKAMDKMLEVNQGLRRRF
STVIEFFSYTPEELIALTQLMGQENEDVITEQEAQVLLPSYTKFYLDETYSEDGDLIRGIDMLGNAGFVRNVVEKARDHR
SFRLDDEDLDAVLASDLTQFSAEQLLRFKELTSADLTEGLSAAVAERKSS
>Mature_609_residues
TRPQSTAEDARNAMVAGLLASGISVNGLQPSHNPQVASQMFRTATTLDPGMCDAWQARILAGDQSIEVLAGAWSSIRTFG
WETRRLGVTDLQFRPEVSDGLFLRLAVTSVESLACAYAAVLVKAKRYAEAAKLLESVEPRHPFDTELVNYVRGMLYFRTK
RWPDVLTQFPEGKQWRHPDLKAAGAAMATSALASLGVFEEAFRRGKEAIEGDRVPRAANIALYTQGMCLRHVGREDEAVE
LLRRVYSRDAKFTPAREALDNNNFRLTLTDPETIEARTDPWDPDSAPTRAQTEAARYARIAAKYLAEGDAELNAMLGMEQ
AKREIKLIKSTTRVNLARAKMGLPVPVTSRHTLLLGPPGTGKTSVARAFTKQLCGLTVLRKPLVVETSRTKLLGRHMADA
EKNTEEMLEGALGGAVFFDEMHTLHEKGYTRGDPYGNAIINTLLLYMENHRDELVVFGAGYAKAMDKMLEVNQGLRRRFS
TVIEFFSYTPEELIALTQLMGQENEDVITEQEAQVLLPSYTKFYLDETYSEDGDLIRGIDMLGNAGFVRNVVEKARDHRS
FRLDDEDLDAVLASDLTQFSAEQLLRFKELTSADLTEGLSAAVAERKSS

Specific function: Shows ATPase activity. Could provide energy for export of ESX-5 substrates [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cbxX/cfxQ family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR000641
- InterPro:   IPR011990 [H]

Pfam domain/function: PF00004 AAA [H]

EC number: NA

Molecular weight: Translated: 67769; Mature: 67638

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPQSTAEDARNAMVAGLLASGISVNGLQPSHNPQVASQMFRTATTLDPGMCDAWQARI
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHH
LAGDQSIEVLAGAWSSIRTFGWETRRLGVTDLQFRPEVSDGLFLRLAVTSVESLACAYAA
HCCCCCHHHHHHHHHHHHHCCCCHHCCCCCCCEECCCCCCCEEEEHHHHHHHHHHHHHHH
VLVKAKRYAEAAKLLESVEPRHPFDTELVNYVRGMLYFRTKRWPDVLTQFPEGKQWRHPD
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCC
LKAAGAAMATSALASLGVFEEAFRRGKEAIEGDRVPRAANIALYTQGMCLRHVGREDEAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHCCCCCHHH
ELLRRVYSRDAKFTPAREALDNNNFRLTLTDPETIEARTDPWDPDSAPTRAQTEAARYAR
HHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IAAKYLAEGDAELNAMLGMEQAKREIKLIKSTTRVNLARAKMGLPVPVTSRHTLLLGPPG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCC
TGKTSVARAFTKQLCGLTVLRKPLVVETSRTKLLGRHMADAEKNTEEMLEGALGGAVFFD
CCHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHH
EMHTLHEKGYTRGDPYGNAIINTLLLYMENHRDELVVFGAGYAKAMDKMLEVNQGLRRRF
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
STVIEFFSYTPEELIALTQLMGQENEDVITEQEAQVLLPSYTKFYLDETYSEDGDLIRGI
HHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCHHHHH
DMLGNAGFVRNVVEKARDHRSFRLDDEDLDAVLASDLTQFSAEQLLRFKELTSADLTEGL
HHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAAVAERKSS
HHHHHHHCCC
>Mature Secondary Structure 
TRPQSTAEDARNAMVAGLLASGISVNGLQPSHNPQVASQMFRTATTLDPGMCDAWQARI
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHH
LAGDQSIEVLAGAWSSIRTFGWETRRLGVTDLQFRPEVSDGLFLRLAVTSVESLACAYAA
HCCCCCHHHHHHHHHHHHHCCCCHHCCCCCCCEECCCCCCCEEEEHHHHHHHHHHHHHHH
VLVKAKRYAEAAKLLESVEPRHPFDTELVNYVRGMLYFRTKRWPDVLTQFPEGKQWRHPD
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCC
LKAAGAAMATSALASLGVFEEAFRRGKEAIEGDRVPRAANIALYTQGMCLRHVGREDEAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHCCCCCHHH
ELLRRVYSRDAKFTPAREALDNNNFRLTLTDPETIEARTDPWDPDSAPTRAQTEAARYAR
HHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IAAKYLAEGDAELNAMLGMEQAKREIKLIKSTTRVNLARAKMGLPVPVTSRHTLLLGPPG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCC
TGKTSVARAFTKQLCGLTVLRKPLVVETSRTKLLGRHMADAEKNTEEMLEGALGGAVFFD
CCHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHH
EMHTLHEKGYTRGDPYGNAIINTLLLYMENHRDELVVFGAGYAKAMDKMLEVNQGLRRRF
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
STVIEFFSYTPEELIALTQLMGQENEDVITEQEAQVLLPSYTKFYLDETYSEDGDLIRGI
HHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCHHHHH
DMLGNAGFVRNVVEKARDHRSFRLDDEDLDAVLASDLTQFSAEQLLRFKELTSADLTEGL
HHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAAVAERKSS
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]