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The map label for this gene is 221230273

Identifier: 221230273

GI number: 221230273

Start: 1822854

End: 1824530

Strand: Reverse

Name: 221230273

Synonym: MLBr_01512

Alternate gene names: NA

Gene position: 1824530-1822854 (Counterclockwise)

Preceding gene: 221230274

Following gene: 221230271

Centisome position: 55.83

GC content: 60.58

Gene sequence:

>1677_bases
GTGGATGTAGCCCTGGCCCCGCCAGGTCCGCTGGCCTCAGGTGGGTTGAGGGTTACAGCGTTGGGAGGCATCAGCGAAAT
CGGCCGCAATATGACGATTTTCGAGCATCTGGGCCGGTTGCTGATCATCGACTGCGGCGTGCTGTCCCCCGGCCACGACG
AGCCCGGTGTCGACCTGATCCTGCCGGACCTGCGCCATATCGAAGACCGGCTCGACGATATCGAGGCGCTCGTGTTGACA
CACGCGCACGAGGATCACATCGGCGCAATCCCGTTCTTGCTCAAGTTGCGGTCTGATATCCCGGTAGTCGGCTCGAAGTT
CACCTTGGCCTTGGTCGCCGCGAAATGCCGTGAACACCGCATCAAACCGGTGTTTGTCGAAGTCGTCGGGGGGCAGAGCT
CTCGGCACGGTGTGTTCGAGTGCGAGTATTTCGCCGTCAACCATTCCATACCGGACGCACTTACTATCGCGGTCTACACG
GGCGCGGGAACGGTATTGCACACCGGAGACATCAAGCTCGATCAATTGCCGCTCGACGGCCGCCCTACCGACTTGCCAGG
CATGTCCCGGCTGGGTGACGCTGGTGTAGACCTTTTCCTGTGCGACTCAACCAATGCCGAGATACCCGGCGTCGGGCCTA
GTGAAAGCGAGGTGGGTCCGACACTGCATAGGCTGATTCAGGGGGCTGATGGCCGTGTCATCGTGGCGTGTTTTGCTTCC
AATGTGGACCGGGTGCAGCAGGTTATAGATGCTGCAGTGGCATTGGGCCGGCGGGTGTCGTTCGTCGGACGGTCGATGGT
CCGCAATATGAGCATCGCGCGTGACCTCGGATTTCTACGAGTAGACGATTCCCATATGATTGACATCGCCGCTGCCGAGA
TGATGGCACCAGAACAGGTAGTGTTGATTACCACTGGCACCCAAGGTGAGCCGATGTCGGCGTTGTCGCGGATGTCACGC
GGCGAGCATCAGAGCATCACGCTGACCTCGGGTGACCTCGTCGTGTTGTCATCATCGCTGATCCCTGGCAACGAGGAGGC
GGTCTACGGTGTCATCGACGCGCTCGCCAAGATTGGAGCTCGAGTTGTCACCAATGCCCAAGCCCGGGTCCATGTTTCGG
GCCACGCCTACGCTGGTGAGCTGCTGTTCTTGTACAACGGCGTGCGGCCGCGTCAGGTTATGCCGGTGCACGGTACTTGG
CGGATGCTTCGCGCTAACGCTAAGCTGGCTGCCAGCACCGGGGTGCCGGAGGATTCAATCTTGATCGCCGAGAACGGCGT
CAGTGTCGACCTGGTTGCTGGTAAGGCGTCGGTCTCCGGAGCGGTGCCGGTCGGCAAGATGTTTGTCGATGGGCTGATTA
CCGGCGATGTCGGCGATGTTATCCTGGGTGAGCGGCTTATCTTGTCGTCGGGTTTTGTCGCGGTCACGGTGGTGGTGAAG
CGCAGCACTGGGCGTCCAGTTACTGTGCCGCAACTGTATTCACGAGGATTTTCCGAAGACCCCAAAGCGCTTGAGCCTGC
AGTTCGCAAGGTCGAGGCAGAGCTGGAGTCGCTGCTCGCCGAGAACGTGACCGACCCGAGCAAGATCGCCCAGGCCGTGC
GCCGCGCCATTGGCAAATGGGTAGGTGAAACCTACCGTCGGCAGCCGATGATCGTGCCGACGGTGATCGAGGTTTGA

Upstream 100 bases:

>100_bases
CGGTTGCCGCAGATGCCGGCAACAGCGGAGCAGATCGATGAGTTGGCTGTCGATATGCGTGCAGCCTCGGTGCTTAGGTG
AACTAAAAGGTGGCTAACAA

Downstream 100 bases:

>100_bases
GGTTATCTGGGCGCGCACTATTGAATTGTACTTTGTGTGCATGTTCTGTTGTGGGGGTGGAGTAAAGGGTGGTGGGTCAG
TGTATTGGCGGGTCGGTGCG

Product: hypothetical protein

Products: NA

Alternate protein names: RNase J [H]

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MDVALAPPGPLASGGLRVTALGGISEIGRNMTIFEHLGRLLIIDCGVLSPGHDEPGVDLILPDLRHIEDRLDDIEALVLT
HAHEDHIGAIPFLLKLRSDIPVVGSKFTLALVAAKCREHRIKPVFVEVVGGQSSRHGVFECEYFAVNHSIPDALTIAVYT
GAGTVLHTGDIKLDQLPLDGRPTDLPGMSRLGDAGVDLFLCDSTNAEIPGVGPSESEVGPTLHRLIQGADGRVIVACFAS
NVDRVQQVIDAAVALGRRVSFVGRSMVRNMSIARDLGFLRVDDSHMIDIAAAEMMAPEQVVLITTGTQGEPMSALSRMSR
GEHQSITLTSGDLVVLSSSLIPGNEEAVYGVIDALAKIGARVVTNAQARVHVSGHAYAGELLFLYNGVRPRQVMPVHGTW
RMLRANAKLAASTGVPEDSILIAENGVSVDLVAGKASVSGAVPVGKMFVDGLITGDVGDVILGERLILSSGFVAVTVVVK
RSTGRPVTVPQLYSRGFSEDPKALEPAVRKVEAELESLLAENVTDPSKIAQAVRRAIGKWVGETYRRQPMIVPTVIEV

Sequences:

>Translated_558_residues
MDVALAPPGPLASGGLRVTALGGISEIGRNMTIFEHLGRLLIIDCGVLSPGHDEPGVDLILPDLRHIEDRLDDIEALVLT
HAHEDHIGAIPFLLKLRSDIPVVGSKFTLALVAAKCREHRIKPVFVEVVGGQSSRHGVFECEYFAVNHSIPDALTIAVYT
GAGTVLHTGDIKLDQLPLDGRPTDLPGMSRLGDAGVDLFLCDSTNAEIPGVGPSESEVGPTLHRLIQGADGRVIVACFAS
NVDRVQQVIDAAVALGRRVSFVGRSMVRNMSIARDLGFLRVDDSHMIDIAAAEMMAPEQVVLITTGTQGEPMSALSRMSR
GEHQSITLTSGDLVVLSSSLIPGNEEAVYGVIDALAKIGARVVTNAQARVHVSGHAYAGELLFLYNGVRPRQVMPVHGTW
RMLRANAKLAASTGVPEDSILIAENGVSVDLVAGKASVSGAVPVGKMFVDGLITGDVGDVILGERLILSSGFVAVTVVVK
RSTGRPVTVPQLYSRGFSEDPKALEPAVRKVEAELESLLAENVTDPSKIAQAVRRAIGKWVGETYRRQPMIVPTVIEV
>Mature_558_residues
MDVALAPPGPLASGGLRVTALGGISEIGRNMTIFEHLGRLLIIDCGVLSPGHDEPGVDLILPDLRHIEDRLDDIEALVLT
HAHEDHIGAIPFLLKLRSDIPVVGSKFTLALVAAKCREHRIKPVFVEVVGGQSSRHGVFECEYFAVNHSIPDALTIAVYT
GAGTVLHTGDIKLDQLPLDGRPTDLPGMSRLGDAGVDLFLCDSTNAEIPGVGPSESEVGPTLHRLIQGADGRVIVACFAS
NVDRVQQVIDAAVALGRRVSFVGRSMVRNMSIARDLGFLRVDDSHMIDIAAAEMMAPEQVVLITTGTQGEPMSALSRMSR
GEHQSITLTSGDLVVLSSSLIPGNEEAVYGVIDALAKIGARVVTNAQARVHVSGHAYAGELLFLYNGVRPRQVMPVHGTW
RMLRANAKLAASTGVPEDSILIAENGVSVDLVAGKASVSGAVPVGKMFVDGLITGDVGDVILGERLILSSGFVAVTVVVK
RSTGRPVTVPQLYSRGFSEDPKALEPAVRKVEAELESLLAENVTDPSKIAQAVRRAIGKWVGETYRRQPMIVPTVIEV

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 59288; Mature: 59288

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVALAPPGPLASGGLRVTALGGISEIGRNMTIFEHLGRLLIIDCGVLSPGHDEPGVDLI
CCCCCCCCCCCCCCCEEEEEECCHHHHCCCEEHHHHCCCEEEEEECCCCCCCCCCCCEEE
LPDLRHIEDRLDDIEALVLTHAHEDHIGAIPFLLKLRSDIPVVGSKFTLALVAAKCREHR
CCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC
IKPVFVEVVGGQSSRHGVFECEYFAVNHSIPDALTIAVYTGAGTVLHTGDIKLDQLPLDG
CCEEEEEEECCCCCCCCCEEEEEEEECCCCCCEEEEEEEECCCEEEEECCEEEECCCCCC
RPTDLPGMSRLGDAGVDLFLCDSTNAEIPGVGPSESEVGPTLHRLIQGADGRVIVACFAS
CCCCCCCHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEECC
NVDRVQQVIDAAVALGRRVSFVGRSMVRNMSIARDLGFLRVDDSHMIDIAAAEMMAPEQV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEHHHHHCCCCEE
VLITTGTQGEPMSALSRMSRGEHQSITLTSGDLVVLSSSLIPGNEEAVYGVIDALAKIGA
EEEEECCCCCHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHCCH
RVVTNAQARVHVSGHAYAGELLFLYNGVRPRQVMPVHGTWRMLRANAKLAASTGVPEDSI
HEEECCCEEEEECCCCCCCEEEEEECCCCCCEEEECCCCEEEEECCCEEEECCCCCCCCE
LIAENGVSVDLVAGKASVSGAVPVGKMFVDGLITGDVGDVILGERLILSSGFVAVTVVVK
EEEECCCEEEEEECCCCCCCCCCHHHHHHHHEEECCCCHHHHCCCHHHCCCCEEEEEEEE
RSTGRPVTVPQLYSRGFSEDPKALEPAVRKVEAELESLLAENVTDPSKIAQAVRRAIGKW
CCCCCCEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VGETYRRQPMIVPTVIEV
HHHHHHCCCCEECEEECC
>Mature Secondary Structure
MDVALAPPGPLASGGLRVTALGGISEIGRNMTIFEHLGRLLIIDCGVLSPGHDEPGVDLI
CCCCCCCCCCCCCCCEEEEEECCHHHHCCCEEHHHHCCCEEEEEECCCCCCCCCCCCEEE
LPDLRHIEDRLDDIEALVLTHAHEDHIGAIPFLLKLRSDIPVVGSKFTLALVAAKCREHR
CCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC
IKPVFVEVVGGQSSRHGVFECEYFAVNHSIPDALTIAVYTGAGTVLHTGDIKLDQLPLDG
CCEEEEEEECCCCCCCCCEEEEEEEECCCCCCEEEEEEEECCCEEEEECCEEEECCCCCC
RPTDLPGMSRLGDAGVDLFLCDSTNAEIPGVGPSESEVGPTLHRLIQGADGRVIVACFAS
CCCCCCCHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEECC
NVDRVQQVIDAAVALGRRVSFVGRSMVRNMSIARDLGFLRVDDSHMIDIAAAEMMAPEQV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEHHHHHCCCCEE
VLITTGTQGEPMSALSRMSRGEHQSITLTSGDLVVLSSSLIPGNEEAVYGVIDALAKIGA
EEEEECCCCCHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHCCH
RVVTNAQARVHVSGHAYAGELLFLYNGVRPRQVMPVHGTWRMLRANAKLAASTGVPEDSI
HEEECCCEEEEECCCCCCCEEEEEECCCCCCEEEECCCCEEEEECCCEEEECCCCCCCCE
LIAENGVSVDLVAGKASVSGAVPVGKMFVDGLITGDVGDVILGERLILSSGFVAVTVVVK
EEEECCCEEEEEECCCCCCCCCCHHHHHHHHEEECCCCHHHHCCCHHHCCCCEEEEEEEE
RSTGRPVTVPQLYSRGFSEDPKALEPAVRKVEAELESLLAENVTDPSKIAQAVRRAIGKW
CCCCCCEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VGETYRRQPMIVPTVIEV
HHHHHHCCCCEECEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]