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The map label for this gene is mshB

Identifier: 221230264

GI number: 221230264

Start: 1801817

End: 1802743

Strand: Reverse

Name: mshB

Synonym: MLBr_01495

Alternate gene names: 221230264

Gene position: 1802743-1801817 (Counterclockwise)

Preceding gene: 221230265

Following gene: 221230263

Centisome position: 55.16

GC content: 61.49

Gene sequence:

>927_bases
ATGTCTGAGACGCCGCGGCTACTGTTCGTGCATGCCCATCCCGACGATGAGAGCCTCAGCAACGGTGCTACCATCGCACA
CTACACCTCGCGTGGGGCGCAAGTGCAGGTTGTCACGTGCACACTCGGTGAGGAAGGCGAGGTCATCGGGGACCGCTGGG
CGGAGCTCACCGTCGATCATGCGGACCAACTCGGTGGCTACCGAATCTTTGAGCTCACCGAAGCGTTGCGGGCGTTGGGG
GTCAGCGCACCCATTTATCTTGGTGGCGCGGGTCGCTGGCGCGACTCGGGCATGCGCGGCACCGCGCCGCGGCGTCGTCA
GCGGTTCATCGACGCCGACGAAAACGAGGCCGTCGGGGCCCTGGTTGCGATCATCCGCGAACTGCGTCCACACGTCGTGG
TGACATATGATCCCCACGGGGGGTACGGCCATCCCGACCATGTCCACACCCACTTTATTACCGCAGCCGCGGTGGCTTCT
TCTGGCGTTGCGGCCGGCCTAGAGGTCGGTGCCGATGAATACCCGGGCAAGCCGTGGAAGGTACCGAAGTTCTACTGGTC
CGTCTTCGCCCTCAGCGCATTTGAAGCTGGGATGAACGCGCTGCAGGGCAAAGATTTGCGGCCCGAGTGGACGATCCCGC
CGCGTGAAGAGTTCTATTTCGGATATTCAGATAAGGACATAGATGCTGTCGTCGAAGCAACCTCAGATGTATGGGCAGCC
AAGACGGCGGCTTTGACGGCACACGCCACCCAAGTCGTCGTTGGCCCGACCGGCCGGGCCTGTGCCTTGTCGAACAACAT
GGTGATGCCAATTTTCGCACAAGAGCACTATGTTCTCGCCGCCGGCTCCGCGGGAAATCGCGATGAGCGCGGTTGGGAAA
CTGATTTGCTAGCGGGACTATGTCTGGATGGATTTGATGCGCGGTAA

Upstream 100 bases:

>100_bases
AGCGCGGAGCACTTGACATCGTCTATATGGGTTAAGTAAGGGATTAGAAGCAATTAAAGTGACTTTCGACGACGTTTAGT
GTTCCGGTTAGGGTGCGTCC

Downstream 100 bases:

>100_bases
ACTGCCAATAAGGTATCTGCGGAAGGAACTGGTTGTGTACCCCGACCTGCAGCATTGGCAGGACCGACTCGACAGTCTGC
CGTGGGAAATCGCATCTGTG

Product: hypothetical protein

Products: NA

Alternate protein names: GlcNAc-Ins deacetylase; N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSETPRLLFVHAHPDDESLSNGATIAHYTSRGAQVQVVTCTLGEEGEVIGDRWAELTVDHADQLGGYRIFELTEALRALG
VSAPIYLGGAGRWRDSGMRGTAPRRRQRFIDADENEAVGALVAIIRELRPHVVVTYDPHGGYGHPDHVHTHFITAAAVAS
SGVAAGLEVGADEYPGKPWKVPKFYWSVFALSAFEAGMNALQGKDLRPEWTIPPREEFYFGYSDKDIDAVVEATSDVWAA
KTAALTAHATQVVVGPTGRACALSNNMVMPIFAQEHYVLAAGSAGNRDERGWETDLLAGLCLDGFDAR

Sequences:

>Translated_308_residues
MSETPRLLFVHAHPDDESLSNGATIAHYTSRGAQVQVVTCTLGEEGEVIGDRWAELTVDHADQLGGYRIFELTEALRALG
VSAPIYLGGAGRWRDSGMRGTAPRRRQRFIDADENEAVGALVAIIRELRPHVVVTYDPHGGYGHPDHVHTHFITAAAVAS
SGVAAGLEVGADEYPGKPWKVPKFYWSVFALSAFEAGMNALQGKDLRPEWTIPPREEFYFGYSDKDIDAVVEATSDVWAA
KTAALTAHATQVVVGPTGRACALSNNMVMPIFAQEHYVLAAGSAGNRDERGWETDLLAGLCLDGFDAR
>Mature_307_residues
SETPRLLFVHAHPDDESLSNGATIAHYTSRGAQVQVVTCTLGEEGEVIGDRWAELTVDHADQLGGYRIFELTEALRALGV
SAPIYLGGAGRWRDSGMRGTAPRRRQRFIDADENEAVGALVAIIRELRPHVVVTYDPHGGYGHPDHVHTHFITAAAVASS
GVAAGLEVGADEYPGKPWKVPKFYWSVFALSAFEAGMNALQGKDLRPEWTIPPREEFYFGYSDKDIDAVVEATSDVWAAK
TAALTAHATQVVVGPTGRACALSNNMVMPIFAQEHYVLAAGSAGNRDERGWETDLLAGLCLDGFDAR

Specific function: Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway

COG id: COG2120

COG function: function code S; Uncharacterized proteins, LmbE homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MshB deacetylase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSHB_MYCLB (B8ZRQ3)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002503680.1
- ProteinModelPortal:   B8ZRQ3
- SMR:   B8ZRQ3
- EnsemblBacteria:   EBMYCT00000086033
- GeneID:   7326913
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000016794
- HOGENOM:   HBG666753
- OMA:   KFYWTVT
- ProtClustDB:   CLSK790994
- HAMAP:   MF_01696
- InterPro:   IPR003737
- InterPro:   IPR017810
- PANTHER:   PTHR12993
- TIGRFAMs:   TIGR03445

Pfam domain/function: PF02585 PIG-L

EC number: =3.5.1.103

Molecular weight: Translated: 33346; Mature: 33214

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETPRLLFVHAHPDDESLSNGATIAHYTSRGAQVQVVTCTLGEEGEVIGDRWAELTVDH
CCCCCCEEEEEECCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCHHHEEEECH
ADQLGGYRIFELTEALRALGVSAPIYLGGAGRWRDSGMRGTAPRRRQRFIDADENEAVGA
HHHCCCEEHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHH
LVAIIRELRPHVVVTYDPHGGYGHPDHVHTHFITAAAVASSGVAAGLEVGADEYPGKPWK
HHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCC
VPKFYWSVFALSAFEAGMNALQGKDLRPEWTIPPREEFYFGYSDKDIDAVVEATSDVWAA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEECCCCCCHHHHHHHHHHHHHH
KTAALTAHATQVVVGPTGRACALSNNMVMPIFAQEHYVLAAGSAGNRDERGWETDLLAGL
HHHEEEEECEEEEECCCCCEEEECCCEEEEEEECCCEEEEECCCCCCCCCCCHHHHHHHH
CLDGFDAR
HCCCCCCC
>Mature Secondary Structure 
SETPRLLFVHAHPDDESLSNGATIAHYTSRGAQVQVVTCTLGEEGEVIGDRWAELTVDH
CCCCCEEEEEECCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCHHHEEEECH
ADQLGGYRIFELTEALRALGVSAPIYLGGAGRWRDSGMRGTAPRRRQRFIDADENEAVGA
HHHCCCEEHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHH
LVAIIRELRPHVVVTYDPHGGYGHPDHVHTHFITAAAVASSGVAAGLEVGADEYPGKPWK
HHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCC
VPKFYWSVFALSAFEAGMNALQGKDLRPEWTIPPREEFYFGYSDKDIDAVVEATSDVWAA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEECCCCCCHHHHHHHHHHHHHH
KTAALTAHATQVVVGPTGRACALSNNMVMPIFAQEHYVLAAGSAGNRDERGWETDLLAGL
HHHEEEEECEEEEECCCCCEEEECCCEEEEEEECCCEEEEECCCCCCCCCCCHHHHHHHH
CLDGFDAR
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA