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The map label for this gene is clpX [H]

Identifier: 221230252

GI number: 221230252

Start: 1779702

End: 1780982

Strand: Reverse

Name: clpX [H]

Synonym: MLBr_01477

Alternate gene names: 221230252

Gene position: 1780982-1779702 (Counterclockwise)

Preceding gene: 221230254

Following gene: 221230251

Centisome position: 54.5

GC content: 55.58

Gene sequence:

>1281_bases
ATGGCGCGTATCGGAGACAGCGGTGACTTGCTGAAGTGCTCGTTTTGCGGGAAGAGTCAGACTCAGGTCAAGAAACTAAT
TGCGGGCCCTGGGGTGTACATCTGTGATGAATGTATTGACCTGTGCAACGAGATCATCGAAGAAGAACTGGCCGATGCTG
ACGATGTGCAGCTTGATGAGCTGCCCAAGCCTGTTGAGATTCGGGAGTTTCTTGAGGGTTACGTCATCGGGCAGGACACC
GCCAAGCGGACGTTGGCTGTCGCGGTCTATAATCACTACAAGCGGATCCAGGCTGGAGAGAAGGGCCGTGACTCTAAGCG
CGAACCGGTAGAGTTGGCCAAATCCAACATCTTGATGCTGGGACCTACTGGTTGCGGCAAGACTTACCTGGCTCAGACGT
TGGCCAAGATGCTCAATGTCCCGTTCGCCATCGCCGACGCCACCGCACTGACCGAGGCCGGTTACGTCGGTGAGGATGTC
GAGAACATCTTGCTTAAGCTGATCCAGGCCGCCGACTATGACGTCAAGCGTGCCGAGACCGGTATTATTTACATCGATGA
GGTCGACAAGATCGCTCGTAAGAGTGAGAACCCATCGATCACTCGTGACGTCTCCGGCGAGGGCGTTCAACAAGCCCTGC
TGAAAATTCTAGAAGGTACCCAAGCGTCGGTTCCCCCGCAAGGTGGCCGCAAGCACCCACACCAAGAATTCATTCAGATC
GATACCACCAACGTGTTGTTCATCGTCGCCGGTGCCTTTGCCGGGTTGGATAAGATTATTTACGAGCGTATTGGCAAACG
CGGCTTAGGCTTTGGTGCCGAAGTCCGCTCCAAAGCCGAAATCGACACCACCGATCATTTCGCCGATGTGATGCCTGAAG
ATCTGATCAAGTTCGGCTTGATCCCTGAGTTCATCGGACGACTCCCGGTGATCGCCTCGGTCATCAATCTGGACATGGAG
TCGTTGGTCAAGATCCTGTCCGAACCGAAGAACGCTTTGGTCAAGCAGTACACTTGGCTTTTCGAAATGGACGGTGTGGA
GCTGGAATTCACTAACGACGCGCTGGAAGCGGTCGCCGACCAAGCAATCCACCGCGGCACCGGCGCTCGTGGCCTGCGGG
CCATCATGGAAGAAGTCCTGCTACCCGTGATGTATGATATTCCTAGCCGCGATGACGTTGCCAAAGTGGTGGTGACCAAG
GAGACTGTGCAGGACAACGTGTTGCCGACAATCGTGCCGCGCAAGCCGTCGCGCACTGAGCGCCGCGATAAGAGTGCCTA
G

Upstream 100 bases:

>100_bases
GGCGCTAACGGTCGCGTCTGCCCCGAACTAGCGGGTAGCGTCGCGGAATACACGCGGCATAGCAAGACGAACGGCGAACA
GGAAGTAGGCCCTTAGCATC

Downstream 100 bases:

>100_bases
TAGTGTGACGGCGGCAGCTGGAAAGTCGGGATCGGCACCAAAAAAATGAATGTGTTCAACGGGCGGCATTACTCCGATGT
GGGTCTGTTATCGGTGAACA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MARIGDSGDLLKCSFCGKSQTQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVQLDELPKPVEIREFLEGYVIGQDT
AKRTLAVAVYNHYKRIQAGEKGRDSKREPVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDV
ENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQI
DTTNVLFIVAGAFAGLDKIIYERIGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFGLIPEFIGRLPVIASVINLDME
SLVKILSEPKNALVKQYTWLFEMDGVELEFTNDALEAVADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK
ETVQDNVLPTIVPRKPSRTERRDKSA

Sequences:

>Translated_426_residues
MARIGDSGDLLKCSFCGKSQTQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVQLDELPKPVEIREFLEGYVIGQDT
AKRTLAVAVYNHYKRIQAGEKGRDSKREPVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDV
ENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQI
DTTNVLFIVAGAFAGLDKIIYERIGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFGLIPEFIGRLPVIASVINLDME
SLVKILSEPKNALVKQYTWLFEMDGVELEFTNDALEAVADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK
ETVQDNVLPTIVPRKPSRTERRDKSA
>Mature_425_residues
ARIGDSGDLLKCSFCGKSQTQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVQLDELPKPVEIREFLEGYVIGQDTA
KRTLAVAVYNHYKRIQAGEKGRDSKREPVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDVE
NILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQID
TTNVLFIVAGAFAGLDKIIYERIGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFGLIPEFIGRLPVIASVINLDMES
LVKILSEPKNALVKQYTWLFEMDGVELEFTNDALEAVADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTKE
TVQDNVLPTIVPRKPSRTERRDKSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=346, Percent_Identity=49.1329479768786, Blast_Score=305, Evalue=6e-83,
Organism=Escherichia coli, GI1786642, Length=413, Percent_Identity=61.7433414043584, Blast_Score=519, Evalue=1e-148,
Organism=Escherichia coli, GI1790366, Length=108, Percent_Identity=46.2962962962963, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71982908, Length=312, Percent_Identity=45.8333333333333, Blast_Score=273, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI71982905, Length=312, Percent_Identity=45.8333333333333, Blast_Score=273, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI71988663, Length=413, Percent_Identity=37.2881355932203, Blast_Score=244, Evalue=5e-65,
Organism=Caenorhabditis elegans, GI71988660, Length=251, Percent_Identity=39.0438247011952, Blast_Score=165, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6319704, Length=428, Percent_Identity=39.9532710280374, Blast_Score=280, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24648291, Length=330, Percent_Identity=46.969696969697, Blast_Score=293, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24648289, Length=330, Percent_Identity=46.969696969697, Blast_Score=293, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46855; Mature: 46724

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIGDSGDLLKCSFCGKSQTQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVQLDE
CCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LPKPVEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGEKGRDSKREPVELAKSNILML
CCCCHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCEEEE
GPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKRAET
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHCCC
GIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQI
CEEEEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEE
DTTNVLFIVAGAFAGLDKIIYERIGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFGL
CCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHHHCHHHHHHHCC
IPEFIGRLPVIASVINLDMESLVKILSEPKNALVKQYTWLFEMDGVELEFTNDALEAVAD
HHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHEEECCEEEEECHHHHHHHHH
QAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTKETVQDNVLPTIVPRKPSRTE
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEHHHHHCCCCCCCCCCCCCCCC
RRDKSA
CCCCCC
>Mature Secondary Structure 
ARIGDSGDLLKCSFCGKSQTQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVQLDE
CCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LPKPVEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGEKGRDSKREPVELAKSNILML
CCCCHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCEEEE
GPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKRAET
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHCCC
GIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQI
CEEEEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEE
DTTNVLFIVAGAFAGLDKIIYERIGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFGL
CCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHHHCHHHHHHHCC
IPEFIGRLPVIASVINLDMESLVKILSEPKNALVKQYTWLFEMDGVELEFTNDALEAVAD
HHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHEEECCEEEEECHHHHHHHHH
QAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTKETVQDNVLPTIVPRKPSRTE
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEHHHHHCCCCCCCCCCCCCCCC
RRDKSA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA