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The map label for this gene is 221229892

Identifier: 221229892

GI number: 221229892

Start: 1058748

End: 1060034

Strand: Reverse

Name: 221229892

Synonym: MLBr_00893

Alternate gene names: NA

Gene position: 1060034-1058748 (Counterclockwise)

Preceding gene: 221229895

Following gene: 221229886

Centisome position: 32.44

GC content: 61.15

Gene sequence:

>1287_bases
ATGAGTAGACAGCAAACGCCCGAAGTGGGCAATAAACACAGGCAGATAGGGCGCTGCTGCCTACTTTGGTTGCTAGCTGT
GACAGCACTGGGACAAGTGGCCTGGCAATTGCTGGGGCACACTCCATACCGCATCGATATTGACATCTATCAGATGGGCG
GTCAGGCTTGGCTAGACGGGCGCCCGCTGTACAGCGGTGATGTGTTATTCCACACACCCATCGGGCTGAATTTGCCGTTC
ACCTACCCCCCGTTGGCCGCCATCGCGTTCTGCCCGTTCGCCTGGTTACACATGCCGGCCGCCAGCGTGGCAATCACGCT
GACAACGTTGATGTTGCTAATCGTCTCGACGATAATCGTACTGACCCGCCTGGACGTGTGGGCCATGTCGCGAGCGGTGC
CCGGGCCGGCCTGGCTGCGCCGGTTGTGGTTGGCAGTGATCATCGTCTCTCCGGCAGCGATCTGGTTAGAGCCAATCAGT
TCGAACTTCGCCTTCGGCCAGATAAACGTCGTGCTGATGACTCTAGTGATCGCTGACTGCGTGCCACGGCGCACGCCATG
GCCACGCGGGCTGATGCTGGGGTTGGGCATCGCCCTGAAACTCACTCCAGCGGTATTCCTGCTCTACTTCGTGCTGCGCC
GCGACAACCGCGCGGCACTGACGTCTTGGGCATCCTTCGCAGGCGCGACGCTGGTTGGTTTCGTGCTAGCGTGGCGGGAT
TCATGGGAATACTGGACTCACACCGTACACAACACCGAACGGATCGGTGCCGCGGCATTAAACACCGACCAGAACATCGC
GGGTGCCCTCGCTAGGCTCGGGCTTGGGGAGCACGAGCGCTTCCTGCTCTGGGCGGCCGGTTGCTTGCTCGTGCTGGCCG
CAACCGCATGGGCGATGTTACGGGTATTGCGAGCTGGCGAGCCAATGCTGGCGGTAATCTGCGTCGCCTTGTTTGGGTTG
GTGGTTTCGCCAGTGTCGTGGTCCCACCACTGGGTATGGATGCTGCCGGCAGTGCTGGTAACAGGAATCTTGAGCTGGCG
ACGGCAGAACGTGGCTGTGGCGGTGATCAGCGCCGCCGGAGTGGCGCTGATGAGATGGACACCCATCGGCCTGCTTCCGC
AACATCAGGAGACAACCGCGGTGTGGTGGCGCCAACTTGCCGGGATGTCCTATGTGTGGTGGGCGTTGGCAGTCATTGTT
GCTACTGGGCTTACCGTGACTACCCGCGTGACGTCGCAGGATTCGGCAACACAGACGCTGCTGACGCCGGTGTCGACTGC
CAGCTGA

Upstream 100 bases:

>100_bases
GGACCACCCTAAAAAGGCAAACCAGCACTCCCCCACAGTGCTGTTAGCCACGCTGTGGCACACCGCAAGCAGGGCGACAC
CCATTACGCTGTTCTGCGGC

Downstream 100 bases:

>100_bases
TCAAGGCCTATCCCACAGCGGTATCAGGTATGCGCACGGCCTCGTTGGTCAATTTGGCACCGCTACTGCTACTGTGGCCC
TTCACACTGGCGGCGTAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-2)-mannosyltransferase; Alpha-mannosyltransferase; Alpha-manT; PPM-dependent mannosyltransferase; Polyprenol-phosphate-mannose alpha-mannosyltransferase; PPM alpha-mannosyltransferase [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSRQQTPEVGNKHRQIGRCCLLWLLAVTALGQVAWQLLGHTPYRIDIDIYQMGGQAWLDGRPLYSGDVLFHTPIGLNLPF
TYPPLAAIAFCPFAWLHMPAASVAITLTTLMLLIVSTIIVLTRLDVWAMSRAVPGPAWLRRLWLAVIIVSPAAIWLEPIS
SNFAFGQINVVLMTLVIADCVPRRTPWPRGLMLGLGIALKLTPAVFLLYFVLRRDNRAALTSWASFAGATLVGFVLAWRD
SWEYWTHTVHNTERIGAAALNTDQNIAGALARLGLGEHERFLLWAAGCLLVLAATAWAMLRVLRAGEPMLAVICVALFGL
VVSPVSWSHHWVWMLPAVLVTGILSWRRQNVAVAVISAAGVALMRWTPIGLLPQHQETTAVWWRQLAGMSYVWWALAVIV
ATGLTVTTRVTSQDSATQTLLTPVSTAS

Sequences:

>Translated_428_residues
MSRQQTPEVGNKHRQIGRCCLLWLLAVTALGQVAWQLLGHTPYRIDIDIYQMGGQAWLDGRPLYSGDVLFHTPIGLNLPF
TYPPLAAIAFCPFAWLHMPAASVAITLTTLMLLIVSTIIVLTRLDVWAMSRAVPGPAWLRRLWLAVIIVSPAAIWLEPIS
SNFAFGQINVVLMTLVIADCVPRRTPWPRGLMLGLGIALKLTPAVFLLYFVLRRDNRAALTSWASFAGATLVGFVLAWRD
SWEYWTHTVHNTERIGAAALNTDQNIAGALARLGLGEHERFLLWAAGCLLVLAATAWAMLRVLRAGEPMLAVICVALFGL
VVSPVSWSHHWVWMLPAVLVTGILSWRRQNVAVAVISAAGVALMRWTPIGLLPQHQETTAVWWRQLAGMSYVWWALAVIV
ATGLTVTTRVTSQDSATQTLLTPVSTAS
>Mature_427_residues
SRQQTPEVGNKHRQIGRCCLLWLLAVTALGQVAWQLLGHTPYRIDIDIYQMGGQAWLDGRPLYSGDVLFHTPIGLNLPFT
YPPLAAIAFCPFAWLHMPAASVAITLTTLMLLIVSTIIVLTRLDVWAMSRAVPGPAWLRRLWLAVIIVSPAAIWLEPISS
NFAFGQINVVLMTLVIADCVPRRTPWPRGLMLGLGIALKLTPAVFLLYFVLRRDNRAALTSWASFAGATLVGFVLAWRDS
WEYWTHTVHNTERIGAAALNTDQNIAGALARLGLGEHERFLLWAAGCLLVLAATAWAMLRVLRAGEPMLAVICVALFGLV
VSPVSWSHHWVWMLPAVLVTGILSWRRQNVAVAVISAAGVALMRWTPIGLLPQHQETTAVWWRQLAGMSYVWWALAVIVA
TGLTVTTRVTSQDSATQTLLTPVSTAS

Specific function: Responsible for the addition of alpha-(1-2) mannose branches to the linear mannan core on the biosynthetic pathway to mature Lipoarabinomannan (LAM) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018584 [H]

Pfam domain/function: PF09594 DUF2029 [H]

EC number: NA

Molecular weight: Translated: 47112; Mature: 46981

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQQTPEVGNKHRQIGRCCLLWLLAVTALGQVAWQLLGHTPYRIDIDIYQMGGQAWLDG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCEEECC
RPLYSGDVLFHTPIGLNLPFTYPPLAAIAFCPFAWLHMPAASVAITLTTLMLLIVSTIIV
CCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LTRLDVWAMSRAVPGPAWLRRLWLAVIIVSPAAIWLEPISSNFAFGQINVVLMTLVIADC
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VPRRTPWPRGLMLGLGIALKLTPAVFLLYFVLRRDNRAALTSWASFAGATLVGFVLAWRD
CCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
SWEYWTHTVHNTERIGAAALNTDQNIAGALARLGLGEHERFLLWAAGCLLVLAATAWAML
CHHHHHHHHCCHHHHCHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RVLRAGEPMLAVICVALFGLVVSPVSWSHHWVWMLPAVLVTGILSWRRQNVAVAVISAAG
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHCC
VALMRWTPIGLLPQHQETTAVWWRQLAGMSYVWWALAVIVATGLTVTTRVTSQDSATQTL
CHHEEECCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHH
LTPVSTAS
CCCCCCCC
>Mature Secondary Structure 
SRQQTPEVGNKHRQIGRCCLLWLLAVTALGQVAWQLLGHTPYRIDIDIYQMGGQAWLDG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCEEECC
RPLYSGDVLFHTPIGLNLPFTYPPLAAIAFCPFAWLHMPAASVAITLTTLMLLIVSTIIV
CCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LTRLDVWAMSRAVPGPAWLRRLWLAVIIVSPAAIWLEPISSNFAFGQINVVLMTLVIADC
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VPRRTPWPRGLMLGLGIALKLTPAVFLLYFVLRRDNRAALTSWASFAGATLVGFVLAWRD
CCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
SWEYWTHTVHNTERIGAAALNTDQNIAGALARLGLGEHERFLLWAAGCLLVLAATAWAML
CHHHHHHHHCCHHHHCHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RVLRAGEPMLAVICVALFGLVVSPVSWSHHWVWMLPAVLVTGILSWRRQNVAVAVISAAG
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHCC
VALMRWTPIGLLPQHQETTAVWWRQLAGMSYVWWALAVIVATGLTVTTRVTSQDSATQTL
CHHEEECCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHH
LTPVSTAS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]