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The map label for this gene is cobT

Identifier: 221229869

GI number: 221229869

Start: 1032099

End: 1033154

Strand: Reverse

Name: cobT

Synonym: MLBr_00868

Alternate gene names: 221229869

Gene position: 1033154-1032099 (Counterclockwise)

Preceding gene: 221229870

Following gene: 221229866

Centisome position: 31.61

GC content: 64.87

Gene sequence:

>1056_bases
ATGGAGTTCGCGCCAGTGTCGCCGCCCGACGGCCACGCCGCAGCAGCTGCCCGCGCTCGCCAGGACACCCTGACCAAGCC
GCGCGGCGCGTTGGGCCGTCTCGAAGATTTGTCGATCTGGGTGGCGTCGTGCCAGGGACAGTGTCCGCCACGCCAGTTCC
AGCGTGCTCGGATAGTAGTGTTCGCCGGTGACCACGGTGTCGCCCGGTCCGGGGTGTCGGCATACCCACCGCAATTGACC
GCTCAGATGGTAGCTAACATCGACCGCGGCGGGGCGGCAATCAACGCACTAGCGAGTATCGCCGACGCGACGATACGAAT
CGCGGATTTAGCTGTCGACGCAGACCCATTGTCGCAGCAGATCGGCATCCATAAAGTGCGACGCGGCAGTGGCGATATCG
CGATCCAGGACGCGTTAACCGAAGACGAGACTGCCCGAGCGATCATAGCCGGTCAACGCATCGCCGATGAGGAAGTCGAC
CGCGGTGCTGACCTGTTAATCGCCGGCGACATCGGAATTGGAAACACCACCGCAGCGGCGGTTTTGGTGGCGGCGTTGAC
GAACGCCGAACCAGTCGCCGTAGTGGGCTTCGGAACCGGGATCGATGACGCCAGTTGGGCACGCAAAACGGCTGCGGTGC
GCGATGCCTTATGTCGGATACGGCTGGTGTTGCCCGATCCGGTCGGGTTGCTGCGCTGCTGCGGCGGCGCCGACCTGGCC
GCTATGGCGGGCTTCTGTGCGCAAGCAGCGGTACGACGTACCCCGTTGCTACTCGACGGCATGGTGGTGACGGCGGCCGC
ACTGGTCGCCGAGCGCCTGGCACCGGGTTCCTGGCAATGGTGGCAGGCCGGTCATCAGTCAACCGAACCGGGTCATGCCC
TGGCTTTGGCAGCTTTGGACTTGGATCCGATTCTGGACCTGCGGATGCGGCTGGGCGAAGGAACCGGTGCTACGGCAGCG
TTACTGGTGCTGCGCGCCGCAGTAGCCGCGTTGACGTCAATGACGACCTTCGCAGAGGCTGGTGTGGCCGGTACGTCGAC
CTCGCCACCATCGTGA

Upstream 100 bases:

>100_bases
GTGTCGGTTAAACCTCTCCTGAAAGCCGTCTCGACCCGGCAATGAAGTTGACCCGAGTGGTAGCCGGGCAGCCGGGACCA
ATCAAGGCACCGAGAACCTG

Downstream 100 bases:

>100_bases
TGCGCTGTCTAGCAACATTTTTCGCATTTGCAACGGCGATTCCCCTCCCCAGGGCCACTAATAGCCCAACAGGTCACGAC
AGGATGACTGCATTGCCGGT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MEFAPVSPPDGHAAAAARARQDTLTKPRGALGRLEDLSIWVASCQGQCPPRQFQRARIVVFAGDHGVARSGVSAYPPQLT
AQMVANIDRGGAAINALASIADATIRIADLAVDADPLSQQIGIHKVRRGSGDIAIQDALTEDETARAIIAGQRIADEEVD
RGADLLIAGDIGIGNTTAAAVLVAALTNAEPVAVVGFGTGIDDASWARKTAAVRDALCRIRLVLPDPVGLLRCCGGADLA
AMAGFCAQAAVRRTPLLLDGMVVTAAALVAERLAPGSWQWWQAGHQSTEPGHALALAALDLDPILDLRMRLGEGTGATAA
LLVLRAAVAALTSMTTFAEAGVAGTSTSPPS

Sequences:

>Translated_351_residues
MEFAPVSPPDGHAAAAARARQDTLTKPRGALGRLEDLSIWVASCQGQCPPRQFQRARIVVFAGDHGVARSGVSAYPPQLT
AQMVANIDRGGAAINALASIADATIRIADLAVDADPLSQQIGIHKVRRGSGDIAIQDALTEDETARAIIAGQRIADEEVD
RGADLLIAGDIGIGNTTAAAVLVAALTNAEPVAVVGFGTGIDDASWARKTAAVRDALCRIRLVLPDPVGLLRCCGGADLA
AMAGFCAQAAVRRTPLLLDGMVVTAAALVAERLAPGSWQWWQAGHQSTEPGHALALAALDLDPILDLRMRLGEGTGATAA
LLVLRAAVAALTSMTTFAEAGVAGTSTSPPS
>Mature_351_residues
MEFAPVSPPDGHAAAAARARQDTLTKPRGALGRLEDLSIWVASCQGQCPPRQFQRARIVVFAGDHGVARSGVSAYPPQLT
AQMVANIDRGGAAINALASIADATIRIADLAVDADPLSQQIGIHKVRRGSGDIAIQDALTEDETARAIIAGQRIADEEVD
RGADLLIAGDIGIGNTTAAAVLVAALTNAEPVAVVGFGTGIDDASWARKTAAVRDALCRIRLVLPDPVGLLRCCGGADLA
AMAGFCAQAAVRRTPLLLDGMVVTAAALVAERLAPGSWQWWQAGHQSTEPGHALALAALDLDPILDLRMRLGEGTGATAA
LLVLRAAVAALTSMTTFAEAGVAGTSTSPPS

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family

Homologues:

Organism=Escherichia coli, GI1788300, Length=345, Percent_Identity=34.7826086956522, Blast_Score=168, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBT_MYCLB (B8ZQK8)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002503285.1
- ProteinModelPortal:   B8ZQK8
- SMR:   B8ZQK8
- EnsemblBacteria:   EBMYCT00000085283
- GeneID:   7326124
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000015770
- HOGENOM:   HBG634399
- OMA:   NEMATFS
- ProtClustDB:   PRK00105
- HAMAP:   MF_00230
- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846
- Gene3D:   G3DSA:1.10.1610.10
- TIGRFAMs:   TIGR03160

Pfam domain/function: PF02277 DBI_PRT; SSF52733 NN:DBI_PRT

EC number: =2.4.2.21

Molecular weight: Translated: 36017; Mature: 36017

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: ACT_SITE 313-313

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFAPVSPPDGHAAAAARARQDTLTKPRGALGRLEDLSIWVASCQGQCPPRQFQRARIVV
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHCCHHHHEEEEEECCCCCCHHHHCCEEEEE
FAGDHGVARSGVSAYPPQLTAQMVANIDRGGAAINALASIADATIRIADLAVDADPLSQQ
EECCCCCHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEHEEECCCHHHHH
IGIHKVRRGSGDIAIQDALTEDETARAIIAGQRIADEEVDRGADLLIAGDIGIGNTTAAA
HCHHHHHCCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHCCCCCEEEECCCCCCCHHHHH
VLVAALTNAEPVAVVGFGTGIDDASWARKTAAVRDALCRIRLVLPDPVGLLRCCGGADLA
HHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHHCCCCCHH
AMAGFCAQAAVRRTPLLLDGMVVTAAALVAERLAPGSWQWWQAGHQSTEPGHALALAALD
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCEEEEEEEC
LDPILDLRMRLGEGTGATAALLVLRAAVAALTSMTTFAEAGVAGTSTSPPS
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MEFAPVSPPDGHAAAAARARQDTLTKPRGALGRLEDLSIWVASCQGQCPPRQFQRARIVV
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHCCHHHHEEEEEECCCCCCHHHHCCEEEEE
FAGDHGVARSGVSAYPPQLTAQMVANIDRGGAAINALASIADATIRIADLAVDADPLSQQ
EECCCCCHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEHEEECCCHHHHH
IGIHKVRRGSGDIAIQDALTEDETARAIIAGQRIADEEVDRGADLLIAGDIGIGNTTAAA
HCHHHHHCCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHCCCCCEEEECCCCCCCHHHHH
VLVAALTNAEPVAVVGFGTGIDDASWARKTAAVRDALCRIRLVLPDPVGLLRCCGGADLA
HHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHHCCCCCHH
AMAGFCAQAAVRRTPLLLDGMVVTAAALVAERLAPGSWQWWQAGHQSTEPGHALALAALD
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCEEEEEEEC
LDPILDLRMRLGEGTGATAALLVLRAAVAALTSMTTFAEAGVAGTSTSPPS
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA