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The map label for this gene is pdtaS [H]

Identifier: 221229828

GI number: 221229828

Start: 952123

End: 953625

Strand: Direct

Name: pdtaS [H]

Synonym: MLBr_00803

Alternate gene names: 221229828

Gene position: 952123-953625 (Clockwise)

Preceding gene: 221229827

Following gene: 221229830

Centisome position: 29.13

GC content: 61.08

Gene sequence:

>1503_bases
ATGTCTACTCTCGGTGATTTGCTTGCTGAACATACGGTGCTGCCGGGCAACGCCGTTGGCCACTTGCATGCGGTGGTAGG
GGAGTGGCAGCTGCTTGCTGACCTGTCCTTTGCCGACTACCTGATGTGGGTCAGCCGTGATGACGGGGTGCTGGTCTGTG
TGGCGCAATGCCGGCCGCATACTGCGCCGACGGTTCTGCAGACCGATGCTGTGGGTAGCGTCGCAAGCGCCGATATGCTG
CCGCTTGTCACTGAGATGTTTACCTCTGGTGCCGTTCAGCATGAAGACGCTGCGGGTCAGCAGTATTCGTGGTTGCCATT
CGGTCGGAACGTTGCGGCTTCTCCGGTGCGGTATGGTGACCAGGTGGTCGCGGTGCTGACGCAGCACCAAGTTGAACTGG
CAGCGCGTCGCAGGCCCGGCAATTTGGAGATCGCCTACTTGGCGTGCGCCACGGATCTTCTGCACATGCTGGCAGAGGGC
ACTTTCCCCGACGTGGGGGACGTGGCGGTGTCGCACTCTACTCCGCGGGCAGGCGATGGTTTCATTCGCCTCGATCGCAA
CGGTGTCGTCGCCTTTGCCAGCCCCAATGCGTTGTCGGCGTTCCACCGTATGGGCCTGACTGCCGAATTGCAAGGCCGCA
ATCTGGTGAAAGTCACTCGGCCACTGCTGTCGGACCCCTTCGAGGCGCAGGAGGTGGCCAAGCATGTGCAGGACTTGCTG
GACGGCGGACCGAGCATGCGAGTGGAGGTTAACGCCGGTGGGGCTACAGTGCTGCTGCGGACGCTGCCGTTGGTGGTGCA
TGGTTCGAGCGTGGGCGCGGCCGTGCTGGTCCGTGACGTCACCGAGGTGAAGCGCCGTGATCGTGCGCTGATCTCTAAGG
ACGCCACGATCCGGGAAATACACCACCGAGTCAAGAATAACCTACAAACTGTCGCGGCGCTGCTGCGGTTGCAGGCCCGG
AGGATGGCCAACGCCGAAGGGCGAGAAGCGTTGATCGAGTCGGTGCGACGGGTGTCGTCGATCGCATTGGTGCACGACGC
GTTGTCGATGTCAGTGGACGAGCAAGTCAACCTTGACGAGGTCATCGATCGGATCCTGCCGATTATGAACGATGTGGCGT
CGGTGGACAGGCCGATTCGGATCAACCGAGTCGGCAACCTGGGCATGCTGGATTCAGACCGTGCCACAGCACTGATCATG
GTGATCACCGAACTAGTGCAGAATGCGATCGAGCATGCATTCGATCCGGCGTCCCAAGAAGGATTTGTGGCGATTAGTGC
TGAGCGTTCGGCGCGTTGGCTCGATGTTGTCGTGCACGACGACGGCCGTGGGTTACCTCAAGGATTCAACTTGGAACGGT
CAGATAGCTTGGGCCTGCAAATTGTGCGCACCTTGGTGTCCTCCGAGTTGGACGGTTCGTTAGGCATGCGGAAAGCACCC
AATCGTGGCACCGATGTGGTGCTGCGGGTGCCGATTGGCCGGCGGGCCCGGTTGCTGCTGTAG

Upstream 100 bases:

>100_bases
TCGGTGGGCGATGTTATTCAGGCCGGCGACCTTATTGCTGTGATCAGCTAGCCGGTGGAGTCTTCGTACCTGCCGCCGAG
AAACGTTCCGGGAGTGACAA

Downstream 100 bases:

>100_bases
CGGACTCGAAACAATGCGGCCCCGATATTATTATCAAGGTCGCACTGTTCCGAGCTGGGTCAGACCCCGCTGCGGGCCTT
TGTCCGGGTGTTCCGACGTT

Product: putative two-component system sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MSTLGDLLAEHTVLPGNAVGHLHAVVGEWQLLADLSFADYLMWVSRDDGVLVCVAQCRPHTAPTVLQTDAVGSVASADML
PLVTEMFTSGAVQHEDAAGQQYSWLPFGRNVAASPVRYGDQVVAVLTQHQVELAARRRPGNLEIAYLACATDLLHMLAEG
TFPDVGDVAVSHSTPRAGDGFIRLDRNGVVAFASPNALSAFHRMGLTAELQGRNLVKVTRPLLSDPFEAQEVAKHVQDLL
DGGPSMRVEVNAGGATVLLRTLPLVVHGSSVGAAVLVRDVTEVKRRDRALISKDATIREIHHRVKNNLQTVAALLRLQAR
RMANAEGREALIESVRRVSSIALVHDALSMSVDEQVNLDEVIDRILPIMNDVASVDRPIRINRVGNLGMLDSDRATALIM
VITELVQNAIEHAFDPASQEGFVAISAERSARWLDVVVHDDGRGLPQGFNLERSDSLGLQIVRTLVSSELDGSLGMRKAP
NRGTDVVLRVPIGRRARLLL

Sequences:

>Translated_500_residues
MSTLGDLLAEHTVLPGNAVGHLHAVVGEWQLLADLSFADYLMWVSRDDGVLVCVAQCRPHTAPTVLQTDAVGSVASADML
PLVTEMFTSGAVQHEDAAGQQYSWLPFGRNVAASPVRYGDQVVAVLTQHQVELAARRRPGNLEIAYLACATDLLHMLAEG
TFPDVGDVAVSHSTPRAGDGFIRLDRNGVVAFASPNALSAFHRMGLTAELQGRNLVKVTRPLLSDPFEAQEVAKHVQDLL
DGGPSMRVEVNAGGATVLLRTLPLVVHGSSVGAAVLVRDVTEVKRRDRALISKDATIREIHHRVKNNLQTVAALLRLQAR
RMANAEGREALIESVRRVSSIALVHDALSMSVDEQVNLDEVIDRILPIMNDVASVDRPIRINRVGNLGMLDSDRATALIM
VITELVQNAIEHAFDPASQEGFVAISAERSARWLDVVVHDDGRGLPQGFNLERSDSLGLQIVRTLVSSELDGSLGMRKAP
NRGTDVVLRVPIGRRARLLL
>Mature_499_residues
STLGDLLAEHTVLPGNAVGHLHAVVGEWQLLADLSFADYLMWVSRDDGVLVCVAQCRPHTAPTVLQTDAVGSVASADMLP
LVTEMFTSGAVQHEDAAGQQYSWLPFGRNVAASPVRYGDQVVAVLTQHQVELAARRRPGNLEIAYLACATDLLHMLAEGT
FPDVGDVAVSHSTPRAGDGFIRLDRNGVVAFASPNALSAFHRMGLTAELQGRNLVKVTRPLLSDPFEAQEVAKHVQDLLD
GGPSMRVEVNAGGATVLLRTLPLVVHGSSVGAAVLVRDVTEVKRRDRALISKDATIREIHHRVKNNLQTVAALLRLQARR
MANAEGREALIESVRRVSSIALVHDALSMSVDEQVNLDEVIDRILPIMNDVASVDRPIRINRVGNLGMLDSDRATALIMV
ITELVQNAIEHAFDPASQEGFVAISAERSARWLDVVVHDDGRGLPQGFNLERSDSLGLQIVRTLVSSELDGSLGMRKAPN
RGTDVVLRVPIGRRARLLL

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: COG3920

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54106; Mature: 53974

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLGDLLAEHTVLPGNAVGHLHAVVGEWQLLADLSFADYLMWVSRDDGVLVCVAQCRPH
CCCHHHHHHHCCCCCCCCHHHHHHHHHCHHHHHHCCHHHHEEEEECCCCEEEEEECCCCC
TAPTVLQTDAVGSVASADMLPLVTEMFTSGAVQHEDAAGQQYSWLPFGRNVAASPVRYGD
CCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCHHCCC
QVVAVLTQHQVELAARRRPGNLEIAYLACATDLLHMLAEGTFPDVGDVAVSHSTPRAGDG
HHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCC
FIRLDRNGVVAFASPNALSAFHRMGLTAELQGRNLVKVTRPLLSDPFEAQEVAKHVQDLL
EEEECCCCEEEEECCHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
DGGPSMRVEVNAGGATVLLRTLPLVVHGSSVGAAVLVRDVTEVKRRDRALISKDATIREI
CCCCCEEEEECCCCCEEHEEHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
HHRVKNNLQTVAALLRLQARRMANAEGREALIESVRRVSSIALVHDALSMSVDEQVNLDE
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VIDRILPIMNDVASVDRPIRINRVGNLGMLDSDRATALIMVITELVQNAIEHAFDPASQE
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
GFVAISAERSARWLDVVVHDDGRGLPQGFNLERSDSLGLQIVRTLVSSELDGSLGMRKAP
CEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
NRGTDVVLRVPIGRRARLLL
CCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
STLGDLLAEHTVLPGNAVGHLHAVVGEWQLLADLSFADYLMWVSRDDGVLVCVAQCRPH
CCHHHHHHHCCCCCCCCHHHHHHHHHCHHHHHHCCHHHHEEEEECCCCEEEEEECCCCC
TAPTVLQTDAVGSVASADMLPLVTEMFTSGAVQHEDAAGQQYSWLPFGRNVAASPVRYGD
CCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCHHCCC
QVVAVLTQHQVELAARRRPGNLEIAYLACATDLLHMLAEGTFPDVGDVAVSHSTPRAGDG
HHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCC
FIRLDRNGVVAFASPNALSAFHRMGLTAELQGRNLVKVTRPLLSDPFEAQEVAKHVQDLL
EEEECCCCEEEEECCHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
DGGPSMRVEVNAGGATVLLRTLPLVVHGSSVGAAVLVRDVTEVKRRDRALISKDATIREI
CCCCCEEEEECCCCCEEHEEHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
HHRVKNNLQTVAALLRLQARRMANAEGREALIESVRRVSSIALVHDALSMSVDEQVNLDE
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VIDRILPIMNDVASVDRPIRINRVGNLGMLDSDRATALIMVITELVQNAIEHAFDPASQE
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
GFVAISAERSARWLDVVVHDDGRGLPQGFNLERSDSLGLQIVRTLVSSELDGSLGMRKAP
CEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
NRGTDVVLRVPIGRRARLLL
CCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]