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The map label for this gene is metX

Identifier: 221229765

GI number: 221229765

Start: 817118

End: 818266

Strand: Reverse

Name: metX

Synonym: MLBr_00682

Alternate gene names: 221229765

Gene position: 818266-817118 (Counterclockwise)

Preceding gene: 221229766

Following gene: 221229763

Centisome position: 25.04

GC content: 63.19

Gene sequence:

>1149_bases
ATGACAATCTCCAAGGTCCCTACCCAGAAGCTGCCGGCCGAAGGCGAGGTCGGCTTGGTCGACATCGGCTCACTTACCAC
CGAAAGCGGTGCCGTCATCGACGATGTCTGCATCGCCGTTCAGCGCTGGGGGGAATTGTCGCCCACGCGAGACAACGTAG
TGATGGTACTGCATGCACTCACCGGTGACTCGCACATCACCGGGCCCGCCGGACCGGGACATCCCACACCCGGCTGGTGG
GACTGGATAGCTGGACCGGGTGCACCAATCGACACCAACCGCTGGTGCGCGATAGCCACCAACGTGCTGGGCGGTTGCCG
TGGCTCCACCGGCCCTAGTTCGCTTGCCCGCGACGGAAAGCCTTGGGGTTCAAGATTTCCGCTGATATCTATACGCGACC
AGGTAGAGGCAGATATCGCTGCACTGGCCGCCATGGGAATTACAAAGGTTGCCGCCGTCGTTGGAGGATCTATGGGCGGG
GCGCGTGCACTGGAATGGATCATCGGCCACCCGGACCAAGTCCGGGCCGGGCTGTTGCTGGCGGTCGGTGTGCGCGCCAC
CGCCGACCAGATCGGCACCCAAACCACCCAAATCGCAGCCATCAAGACAGACCCGAACTGGCAAGGCGGTGACTACTACG
AGACAGGGAGGGCACCAGAGAACGGCTTGACAATTGCCCGCCGCTTCGCCCACCTGACCTACCGCAGCGAGGTCGAGCTC
GACACCCGGTTTGCCAACAACAACCAAGGCAATGAGGACCCGGCGACGGGCGGGCGTTACGCAGTGCAGAGTTACCTAGA
GCACCAGGGTGACAAGCTATTGGCCCGCTTTGACGCAGGCAGCTACGTGGTCTTGACCGAAACGCTGAACAGCCACGACG
TTGGCCGGGGCCGCGGAGGGATCGGTACAGCGCTGCGCGGGTGCCCGGTACCGGTGGTGGTGGGTGGCATTACCTCGGAT
CGGCTCTACCCACTGCGCTTGCAGCAGGAGCTGGCCGAGATGCTGCCGGGCTGCACCGGGCTGCAGGTTGTAGACTCCAC
CTACGGGCACGACGGCTTCCTGGTGGAATCCGAGGCCGTCGGCAAATTGATCCGTCAAACCCTCGAATTGGCCGACGTGG
GTTCCAAGGAAGACGCGTGTTCGCAATGA

Upstream 100 bases:

>100_bases
AAAACATCGACGACATCCTGACCGACCTGATGTTCGGCTTCACGACGACTTGCCAAAGCAATGATCCGCAGGCTATAGCA
GCCTTTTGAGGGCTCCTGAC

Downstream 100 bases:

>100_bases
CCCGCGCTAGTGATGATTTCCAGCAACGGGGTAACAGGACGCAACAAGTCACACTTACGCAACCTAGCCACGACCGCTCC
CTGTCGTTCGGCTCCGCGGC

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MTISKVPTQKLPAEGEVGLVDIGSLTTESGAVIDDVCIAVQRWGELSPTRDNVVMVLHALTGDSHITGPAGPGHPTPGWW
DWIAGPGAPIDTNRWCAIATNVLGGCRGSTGPSSLARDGKPWGSRFPLISIRDQVEADIAALAAMGITKVAAVVGGSMGG
ARALEWIIGHPDQVRAGLLLAVGVRATADQIGTQTTQIAAIKTDPNWQGGDYYETGRAPENGLTIARRFAHLTYRSEVEL
DTRFANNNQGNEDPATGGRYAVQSYLEHQGDKLLARFDAGSYVVLTETLNSHDVGRGRGGIGTALRGCPVPVVVGGITSD
RLYPLRLQQELAEMLPGCTGLQVVDSTYGHDGFLVESEAVGKLIRQTLELADVGSKEDACSQ

Sequences:

>Translated_382_residues
MTISKVPTQKLPAEGEVGLVDIGSLTTESGAVIDDVCIAVQRWGELSPTRDNVVMVLHALTGDSHITGPAGPGHPTPGWW
DWIAGPGAPIDTNRWCAIATNVLGGCRGSTGPSSLARDGKPWGSRFPLISIRDQVEADIAALAAMGITKVAAVVGGSMGG
ARALEWIIGHPDQVRAGLLLAVGVRATADQIGTQTTQIAAIKTDPNWQGGDYYETGRAPENGLTIARRFAHLTYRSEVEL
DTRFANNNQGNEDPATGGRYAVQSYLEHQGDKLLARFDAGSYVVLTETLNSHDVGRGRGGIGTALRGCPVPVVVGGITSD
RLYPLRLQQELAEMLPGCTGLQVVDSTYGHDGFLVESEAVGKLIRQTLELADVGSKEDACSQ
>Mature_381_residues
TISKVPTQKLPAEGEVGLVDIGSLTTESGAVIDDVCIAVQRWGELSPTRDNVVMVLHALTGDSHITGPAGPGHPTPGWWD
WIAGPGAPIDTNRWCAIATNVLGGCRGSTGPSSLARDGKPWGSRFPLISIRDQVEADIAALAAMGITKVAAVVGGSMGGA
RALEWIIGHPDQVRAGLLLAVGVRATADQIGTQTTQIAAIKTDPNWQGGDYYETGRAPENGLTIARRFAHLTYRSEVELD
TRFANNNQGNEDPATGGRYAVQSYLEHQGDKLLARFDAGSYVVLTETLNSHDVGRGRGGIGTALRGCPVPVVVGGITSDR
LYPLRLQQELAEMLPGCTGLQVVDSTYGHDGFLVESEAVGKLIRQTLELADVGSKEDACSQ

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=229, Percent_Identity=34.061135371179, Blast_Score=129, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_MYCLB (B8ZUV9)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002503181.1
- ProteinModelPortal:   B8ZUV9
- SMR:   B8ZUV9
- EnsemblBacteria:   EBMYCT00000085285
- GeneID:   7326196
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000016704
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- ProtClustDB:   PRK00175
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 40299; Mature: 40168

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: ACT_SITE 157-157 ACT_SITE 350-350

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISKVPTQKLPAEGEVGLVDIGSLTTESGAVIDDVCIAVQRWGELSPTRDNVVMVLHAL
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEE
TGDSHITGPAGPGHPTPGWWDWIAGPGAPIDTNRWCAIATNVLGGCRGSTGPSSLARDGK
CCCCEECCCCCCCCCCCCCHHHHCCCCCCCCCCCEEEEHHHHHHCCCCCCCHHHHHCCCC
PWGSRFPLISIRDQVEADIAALAAMGITKVAAVVGGSMGGARALEWIIGHPDQVRAGLLL
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHCEEE
AVGVRATADQIGTQTTQIAAIKTDPNWQGGDYYETGRAPENGLTIARRFAHLTYRSEVEL
EECCHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEE
DTRFANNNQGNEDPATGGRYAVQSYLEHQGDKLLARFDAGSYVVLTETLNSHDVGRGRGG
EEEECCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCCCCCC
IGTALRGCPVPVVVGGITSDRLYPLRLQQELAEMLPGCTGLQVVDSTYGHDGFLVESEAV
CCHHHCCCCCCEEEECCCCCCEEHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEECHHHH
GKLIRQTLELADVGSKEDACSQ
HHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TISKVPTQKLPAEGEVGLVDIGSLTTESGAVIDDVCIAVQRWGELSPTRDNVVMVLHAL
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEE
TGDSHITGPAGPGHPTPGWWDWIAGPGAPIDTNRWCAIATNVLGGCRGSTGPSSLARDGK
CCCCEECCCCCCCCCCCCCHHHHCCCCCCCCCCCEEEEHHHHHHCCCCCCCHHHHHCCCC
PWGSRFPLISIRDQVEADIAALAAMGITKVAAVVGGSMGGARALEWIIGHPDQVRAGLLL
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHCEEE
AVGVRATADQIGTQTTQIAAIKTDPNWQGGDYYETGRAPENGLTIARRFAHLTYRSEVEL
EECCHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEE
DTRFANNNQGNEDPATGGRYAVQSYLEHQGDKLLARFDAGSYVVLTETLNSHDVGRGRGG
EEEECCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCCCCCC
IGTALRGCPVPVVVGGITSDRLYPLRLQQELAEMLPGCTGLQVVDSTYGHDGFLVESEAV
CCHHHCCCCCCEEEECCCCCCEEHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEECHHHH
GKLIRQTLELADVGSKEDACSQ
HHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA