Click here to switch to the map view.

The map label for this gene is pyrF

Identifier: 221229671

GI number: 221229671

Start: 653003

End: 653851

Strand: Direct

Name: pyrF

Synonym: MLBr_00537

Alternate gene names: 221229671

Gene position: 653003-653851 (Clockwise)

Preceding gene: 221229670

Following gene: 221229672

Centisome position: 19.98

GC content: 63.96

Gene sequence:

>849_bases
ATGACCGGTTTTGGCGCTCGGCTGGTCGAGGCGACGTCACGCCGCGGGCAGCTGTGTTTGGGTATAGACCCGCATCCTGA
GTTGCTGCGCGCATGGGACTTGCCGACTACCGCGGACGGGCTGGCTGCGTTCTGCGACATCTGTGTGGAGGCGTTTTCCG
GTTTCGCCATAGTCAAACCACAGGTGGCGTTTTTTGAAGCCTACGGCGCTGCCGGCTTCGCGGTGCTGGAGTATACCATC
GCCGCGTTGCGGTCTGTCGGCGTACTGGTGTTGGCTGACGCCAAACGAGGGGATATCGGGTCGACGATGGCGGCCTACGC
TGCTGCTTGGGCAGGCAATTCGCCGTTGGCCGCCGACGCGGTGACGGCCTCGCCGTATCTTGGGTTCGGCTCGTTGCGGC
CGCTACTAGAAGTAGCCGCGGCACACGACCGGGGCGTGTTCGTGCTAGCATCAACGTCCAACCTTGAGGGTGCCACCGTC
CAGCGCGCCACGTTTGACGGTCGCATAGTAGCTCAACTGATTGTTGACCAGGCGGCTTTCGTCAACAGAGAAATGAACCG
GTCCTTCCATCGGTCTGAGCCGGGGTGCTTGGGATATGTTGGAGTAGTCGTAGGCGCAACGGTTTTCGGGGCGCCGGATG
TCAGCGCGCTGGGTGGACCGGTGTTGGTGCCCGGAGTGGGGGCGCAGGGTGGACACCCCGAGGCGCTCGGCGGCCTGGGT
GGGGCGGCGCCAGGTCAGCTGTTGCCTGCGGTGTCACGTGCAGTGTTGCGCGCCGGCCCCGGTGTTTCAGAGCTGCGAGC
AGCTGGCGAACAGATGCGTGATGCAGTCGCCTATCTCGCTGCTGTTTAG

Upstream 100 bases:

>100_bases
AGGGCATCGAAGCGGGGATCCGAGGTGACATCGGCGTACGGTCGCTGCAAGAACTGCACAGTGCCATTGGTGCGGGGATC
GCGGCTGATAATGAGGTCCA

Downstream 100 bases:

>100_bases
TGTTGAGTGCCGCAGCCTGTCATTGCGAGACGATTGCGTCACCGGTAAGGCTGCTCGGCCAGAATATTGAAATTCATCGG
TGGCCTCTATCTGCAGATTT

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTGFGARLVEATSRRGQLCLGIDPHPELLRAWDLPTTADGLAAFCDICVEAFSGFAIVKPQVAFFEAYGAAGFAVLEYTI
AALRSVGVLVLADAKRGDIGSTMAAYAAAWAGNSPLAADAVTASPYLGFGSLRPLLEVAAAHDRGVFVLASTSNLEGATV
QRATFDGRIVAQLIVDQAAFVNREMNRSFHRSEPGCLGYVGVVVGATVFGAPDVSALGGPVLVPGVGAQGGHPEALGGLG
GAAPGQLLPAVSRAVLRAGPGVSELRAAGEQMRDAVAYLAAV

Sequences:

>Translated_282_residues
MTGFGARLVEATSRRGQLCLGIDPHPELLRAWDLPTTADGLAAFCDICVEAFSGFAIVKPQVAFFEAYGAAGFAVLEYTI
AALRSVGVLVLADAKRGDIGSTMAAYAAAWAGNSPLAADAVTASPYLGFGSLRPLLEVAAAHDRGVFVLASTSNLEGATV
QRATFDGRIVAQLIVDQAAFVNREMNRSFHRSEPGCLGYVGVVVGATVFGAPDVSALGGPVLVPGVGAQGGHPEALGGLG
GAAPGQLLPAVSRAVLRAGPGVSELRAAGEQMRDAVAYLAAV
>Mature_281_residues
TGFGARLVEATSRRGQLCLGIDPHPELLRAWDLPTTADGLAAFCDICVEAFSGFAIVKPQVAFFEAYGAAGFAVLEYTIA
ALRSVGVLVLADAKRGDIGSTMAAYAAAWAGNSPLAADAVTASPYLGFGSLRPLLEVAAAHDRGVFVLASTSNLEGATVQ
RATFDGRIVAQLIVDQAAFVNREMNRSFHRSEPGCLGYVGVVVGATVFGAPDVSALGGPVLVPGVGAQGGHPEALGGLGG
AAPGQLLPAVSRAVLRAGPGVSELRAAGEQMRDAVAYLAAV

Specific function: Unknown

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 2 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRF_MYCLB (B8ZUL5)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002503087.1
- ProteinModelPortal:   B8ZUL5
- SMR:   B8ZUL5
- EnsemblBacteria:   EBMYCT00000086410
- GeneID:   7327267
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000017172
- HOGENOM:   HBG348634
- OMA:   KPQSAFF
- ProtClustDB:   PRK00125
- HAMAP:   MF_01215
- InterPro:   IPR013785
- InterPro:   IPR018089
- InterPro:   IPR011995
- InterPro:   IPR001754
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00934
- TIGRFAMs:   TIGR02127

Pfam domain/function: PF00215 OMPdecase; SSF51366 RibP_bind_barrel

EC number: =4.1.1.23

Molecular weight: Translated: 28678; Mature: 28547

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00156 OMPDECASE

Important sites: ACT_SITE 95-95

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGFGARLVEATSRRGQLCLGIDPHPELLRAWDLPTTADGLAAFCDICVEAFSGFAIVKP
CCCCHHHHHHHHCCCCCEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEECC
QVAFFEAYGAAGFAVLEYTIAALRSVGVLVLADAKRGDIGSTMAAYAAAWAGNSPLAADA
HHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCC
VTASPYLGFGSLRPLLEVAAAHDRGVFVLASTSNLEGATVQRATFDGRIVAQLIVDQAAF
CCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHH
VNREMNRSFHRSEPGCLGYVGVVVGATVFGAPDVSALGGPVLVPGVGAQGGHPEALGGLG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCEEECCCCCCCCCCHHHCCCC
GAAPGQLLPAVSRAVLRAGPGVSELRAAGEQMRDAVAYLAAV
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TGFGARLVEATSRRGQLCLGIDPHPELLRAWDLPTTADGLAAFCDICVEAFSGFAIVKP
CCCHHHHHHHHCCCCCEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEECC
QVAFFEAYGAAGFAVLEYTIAALRSVGVLVLADAKRGDIGSTMAAYAAAWAGNSPLAADA
HHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCC
VTASPYLGFGSLRPLLEVAAAHDRGVFVLASTSNLEGATVQRATFDGRIVAQLIVDQAAF
CCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHH
VNREMNRSFHRSEPGCLGYVGVVVGATVFGAPDVSALGGPVLVPGVGAQGGHPEALGGLG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCEEECCCCCCCCCCHHHCCCC
GAAPGQLLPAVSRAVLRAGPGVSELRAAGEQMRDAVAYLAAV
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA