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The map label for this gene is glmM

Identifier: 221229577

GI number: 221229577

Start: 458001

End: 459392

Strand: Direct

Name: glmM

Synonym: MLBr_00366

Alternate gene names: 221229577

Gene position: 458001-459392 (Clockwise)

Preceding gene: 221229576

Following gene: 221229580

Centisome position: 14.01

GC content: 63.07

Gene sequence:

>1392_bases
ATGGGTCGACTATTCGGCACTGATGGTGTTCGCGGAGTGGCCAATCGTGAGTTGACCCCTGAGCTCGTGCTGGCCCTAGG
CGCGGCGGCGGCACGGTGCTTGGCCAACTCGGGCGAACCGGGGCGGCGGGTAGCCGTGATCGGTCGCGATCCGCGGGCCA
GCGGTGAGATGCTTGAGGCCGCTGTCATCGCTGGCCTGACCAGTGCGGGTGTTGACGCACTGCGGGTTGGAGTGCTCCCG
ACACCTGCGGTGGCGTATCTGACCGGTGCCTACGACGCCGACTTCGGGGTGATGATTTCGGCGTCCCACAACCCGATGGT
CGACAACGGCATCAAGATCTTCGGGCCGGGCGGTCATAAATTGGACGACGACACCGAAGACCAGATCGAAGACCTGGTTA
CCGGCGGGCCCGGGTTGCGCCCGGCCGGCGTGGCGATCGGTCGCGTCATCGACGCCGAGGATGCTACGGAACGTTACTTG
CGCCACGTGGGCAAAGCCAGCACCATACGGCTCGACGGCTTGACGGTGGTCGTCGACTGCGCACATGGCGCGGCCTCGTC
AGCGGCACCGCGCGCGTATCGCGCAGCCGGTGCCCGGGTCATCGCGATCAACGCCGATCCCAACGGCATCAACATCAACG
ATCGCTGTGGATCTACGGACCTGGGTTCGTTGCGTTCAGCGGTGCTTGCCCACCGTGCTGACCTAGGCCTGGCGCACGAC
GGAGACGCCGACCGGTGTCTTGCCGTTGATGCTAATGGTGATCTCGTCGACGGCGACGCCATCATGGTCGTGCTTGCGCT
TGCGATGCAAGAAGCCGGCGAACTGTCTTCCAACACTTTGGTGACTACCGTGATGAGCAATCTGGGGCTGCACCTGGCCA
TGCGTTCGGTCGGCGTCATCGTGCGTACAACCGACGTCGGCGACCGTTATGTCTTGGAGGAGTTGCGCGCTGGTGACTTT
AGTCTCGGCGGCGAGCAATCCGGCCATATCGTGATGCCCGCATTGGGCTCCACCGGAGACGGTATCATCACTGGGTTGCG
ATTGATGACCCGCATGGTGCAGACCAGCTCTTCGCTGGCTGCCCTCGCGTCGGCGATGCGGGCGTTGCCGCAGGTGTTAA
TCAATGTCGAGGTTGCAGACAAAACCACTGCTGCCGCTGCGCCTTTAGTGCAGACGGCGGTCGAGACTGCTGAGGTCGAA
TTGGGGAATACAGGTCGAATCCTGTTGCGTCCCTCAGGAACTGAGCCGATGATCCGGGTCATGGTGGAGGCAGCCGAAGA
AGATGTCGCGCACCGAGTGGCGACGCGAGTCGCTGCAGCGGTGAGTGCTCAGGGGTCACCTCTCCGATGCTGGAACCCCG
ACGCGATATCGGGCGTCGAATTAAGATTATGA

Upstream 100 bases:

>100_bases
ATCATTGGTGTGTCGACGGCTAAACTTGCACGGTTTCGGCTAGAAAGACACATGGGCACGTATAGGTGCCAGAGTCATTA
ATTGCGAGAGGTTTGTCCGC

Downstream 100 bases:

>100_bases
GACCTATTGCTGATACCAGTATCGACGTTGCGGCCGCATTTATCGACGGTGTTATCACCGTACCACTTGCTTGGGGTGGC
TTTTGGCGGCTTCGGCTTCA

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MGRLFGTDGVRGVANRELTPELVLALGAAAARCLANSGEPGRRVAVIGRDPRASGEMLEAAVIAGLTSAGVDALRVGVLP
TPAVAYLTGAYDADFGVMISASHNPMVDNGIKIFGPGGHKLDDDTEDQIEDLVTGGPGLRPAGVAIGRVIDAEDATERYL
RHVGKASTIRLDGLTVVVDCAHGAASSAAPRAYRAAGARVIAINADPNGININDRCGSTDLGSLRSAVLAHRADLGLAHD
GDADRCLAVDANGDLVDGDAIMVVLALAMQEAGELSSNTLVTTVMSNLGLHLAMRSVGVIVRTTDVGDRYVLEELRAGDF
SLGGEQSGHIVMPALGSTGDGIITGLRLMTRMVQTSSSLAALASAMRALPQVLINVEVADKTTAAAAPLVQTAVETAEVE
LGNTGRILLRPSGTEPMIRVMVEAAEEDVAHRVATRVAAAVSAQGSPLRCWNPDAISGVELRL

Sequences:

>Translated_463_residues
MGRLFGTDGVRGVANRELTPELVLALGAAAARCLANSGEPGRRVAVIGRDPRASGEMLEAAVIAGLTSAGVDALRVGVLP
TPAVAYLTGAYDADFGVMISASHNPMVDNGIKIFGPGGHKLDDDTEDQIEDLVTGGPGLRPAGVAIGRVIDAEDATERYL
RHVGKASTIRLDGLTVVVDCAHGAASSAAPRAYRAAGARVIAINADPNGININDRCGSTDLGSLRSAVLAHRADLGLAHD
GDADRCLAVDANGDLVDGDAIMVVLALAMQEAGELSSNTLVTTVMSNLGLHLAMRSVGVIVRTTDVGDRYVLEELRAGDF
SLGGEQSGHIVMPALGSTGDGIITGLRLMTRMVQTSSSLAALASAMRALPQVLINVEVADKTTAAAAPLVQTAVETAEVE
LGNTGRILLRPSGTEPMIRVMVEAAEEDVAHRVATRVAAAVSAQGSPLRCWNPDAISGVELRL
>Mature_462_residues
GRLFGTDGVRGVANRELTPELVLALGAAAARCLANSGEPGRRVAVIGRDPRASGEMLEAAVIAGLTSAGVDALRVGVLPT
PAVAYLTGAYDADFGVMISASHNPMVDNGIKIFGPGGHKLDDDTEDQIEDLVTGGPGLRPAGVAIGRVIDAEDATERYLR
HVGKASTIRLDGLTVVVDCAHGAASSAAPRAYRAAGARVIAINADPNGININDRCGSTDLGSLRSAVLAHRADLGLAHDG
DADRCLAVDANGDLVDGDAIMVVLALAMQEAGELSSNTLVTTVMSNLGLHLAMRSVGVIVRTTDVGDRYVLEELRAGDFS
LGGEQSGHIVMPALGSTGDGIITGLRLMTRMVQTSSSLAALASAMRALPQVLINVEVADKTTAAAAPLVQTAVETAEVEL
GNTGRILLRPSGTEPMIRVMVEAAEEDVAHRVATRVAAAVSAQGSPLRCWNPDAISGVELRL

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=448, Percent_Identity=45.3125, Blast_Score=329, Evalue=2e-91,
Organism=Escherichia coli, GI1788361, Length=451, Percent_Identity=27.9379157427938, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1786904, Length=360, Percent_Identity=26.1111111111111, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_MYCLB (B8ZUC1)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002502993.1
- ProteinModelPortal:   B8ZUC1
- SMR:   B8ZUC1
- EnsemblBacteria:   EBMYCT00000086048
- GeneID:   7325949
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000015909
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- ProtClustDB:   PRK14318
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 47645; Mature: 47514

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRLFGTDGVRGVANRELTPELVLALGAAAARCLANSGEPGRRVAVIGRDPRASGEMLEA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHH
AVIAGLTSAGVDALRVGVLPTPAVAYLTGAYDADFGVMISASHNPMVDNGIKIFGPGGHK
HHHHHHHHCCCHHEEECCCCCCHHHHEECCCCCCCCEEEECCCCCCCCCCEEEEECCCCC
LDDDTEDQIEDLVTGGPGLRPAGVAIGRVIDAEDATERYLRHVGKASTIRLDGLTVVVDC
CCCCCHHHHHHHHCCCCCCCCHHHHHHEEECCCHHHHHHHHHCCCCCEEEECCEEEEEEC
AHGAASSAAPRAYRAAGARVIAINADPNGININDRCGSTDLGSLRSAVLAHRADLGLAHD
CCCCCCCCCCHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
GDADRCLAVDANGDLVDGDAIMVVLALAMQEAGELSSNTLVTTVMSNLGLHLAMRSVGVI
CCCCCEEEEECCCCEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHCCEE
VRTTDVGDRYVLEELRAGDFSLGGEQSGHIVMPALGSTGDGIITGLRLMTRMVQTSSSLA
EEEECCCCHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCHHHH
ALASAMRALPQVLINVEVADKTTAAAAPLVQTAVETAEVELGNTGRILLRPSGTEPMIRV
HHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHEEEECCCCEEEEECCCCCHHHHH
MVEAAEEDVAHRVATRVAAAVSAQGSPLRCWNPDAISGVELRL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCEEEEC
>Mature Secondary Structure 
GRLFGTDGVRGVANRELTPELVLALGAAAARCLANSGEPGRRVAVIGRDPRASGEMLEA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHH
AVIAGLTSAGVDALRVGVLPTPAVAYLTGAYDADFGVMISASHNPMVDNGIKIFGPGGHK
HHHHHHHHCCCHHEEECCCCCCHHHHEECCCCCCCCEEEECCCCCCCCCCEEEEECCCCC
LDDDTEDQIEDLVTGGPGLRPAGVAIGRVIDAEDATERYLRHVGKASTIRLDGLTVVVDC
CCCCCHHHHHHHHCCCCCCCCHHHHHHEEECCCHHHHHHHHHCCCCCEEEECCEEEEEEC
AHGAASSAAPRAYRAAGARVIAINADPNGININDRCGSTDLGSLRSAVLAHRADLGLAHD
CCCCCCCCCCHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
GDADRCLAVDANGDLVDGDAIMVVLALAMQEAGELSSNTLVTTVMSNLGLHLAMRSVGVI
CCCCCEEEEECCCCEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHCCEE
VRTTDVGDRYVLEELRAGDFSLGGEQSGHIVMPALGSTGDGIITGLRLMTRMVQTSSSLA
EEEECCCCHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCHHHH
ALASAMRALPQVLINVEVADKTTAAAAPLVQTAVETAEVELGNTGRILLRPSGTEPMIRV
HHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHEEEECCCCEEEEECCCCCHHHHH
MVEAAEEDVAHRVATRVAAAVSAQGSPLRCWNPDAISGVELRL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA