Click here to switch to the map view.

The map label for this gene is pheA

Identifier: 221229398

GI number: 221229398

Start: 98452

End: 99420

Strand: Direct

Name: pheA

Synonym: MLBr_00078

Alternate gene names: 221229398

Gene position: 98452-99420 (Clockwise)

Preceding gene: 221229397

Following gene: 221229399

Centisome position: 3.01

GC content: 65.22

Gene sequence:

>969_bases
GTGAGTGTGGCCCGCATCGCTTACCTTGGTCCTGAAGGAACCTTCACCGAGGCAGCGCTGCTCAGGATGACGGCCGCCGG
ACTGGTTCCCGATACCGGGCCGGACGGCTTACGGCGGTGGCCGACCGAGAGCACGCCCGCCGCGCTCGACGCTGTTCGTG
GCGGTGCTGCGGATTATGCGTGCGTGCCTATCGAGAACTCCATCGACGGGTCGGTGGCTCCCACGTTGGACAACTTAGCC
ATCGGTTCGCCCCTGCAAGTGTTCGCTGAGACAACGCTAGATGTGGAGTTCAACATCGTTGTCAAACCCGGCATCACCGC
CGCCGACATACGCACGTTGGCGGCCTTCCCAGTGGCGGCGGCGCAGGTGCGGCAATGGCTTGCTGCCCATCTGGCTGGCG
CTGAACTGCGGCCGGCGTATTCCAACGCCGACGCGGCTCGGCAGGTTGCCTACGGACAGGTGGATGCAGCAGTTACGTCG
CCGCTGGCCGCCACCCGCTGGGGGTTGATAGCGCTCGCCGCCGGCATCGTCGACGAACCCAACGCCCGGACTCGTTTCGT
TCTGGTTGGGATGCCGGGGCCGCCTCCGGCCCGCACCGGAACCGATCGTACTTCGGCGGTGCTTCGCATCGACAACGCGC
CTGGCATGTTGGTGGCCGCGCTGGCTGAATTCGGCATCCGCGGCATTGACCTCACCCGAATTGAATCCCGGCCGACCCGC
ACCGAACTTGGCACCTACTTGTTCTTCGTGGACTGCGTAGGACACATCGATGATGGTGTTGTCGCCGAGGCACTGAAGGC
GTTACATCGTCGTTGTGCGGACGTGTGTTATCTCGGTTCCTGGCCGGCGGGCCTGGCTACTGGTCCAACGGTGTCACCGC
CGCCGCCGGACGAAGCTTCGCGCTGGTTGGCCAGGCTGCGGGCAGGCAAACCCGATCAGGCCTCTGAACCAGGGGGCGGC
AAGCTATGA

Upstream 100 bases:

>100_bases
CGGTAGACGGGACATGCTGGTGTGCTCAGCGAACGCATCTACATCTTGCCGTCGCGCGTATTAAGTGAGAGTAGCTGGTC
GATTCGGTGCCACTAGGGTT

Downstream 100 bases:

>100_bases
GCAGTCGTTTGGTGCTGCTGCGGCATGGCCAGTCATACGGCAATGTCGAGGGCAGGTTAGACACTCGGCCACCGGGAGCG
TCGCTGACGCCGTTCGGTCG

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MSVARIAYLGPEGTFTEAALLRMTAAGLVPDTGPDGLRRWPTESTPAALDAVRGGAADYACVPIENSIDGSVAPTLDNLA
IGSPLQVFAETTLDVEFNIVVKPGITAADIRTLAAFPVAAAQVRQWLAAHLAGAELRPAYSNADAARQVAYGQVDAAVTS
PLAATRWGLIALAAGIVDEPNARTRFVLVGMPGPPPARTGTDRTSAVLRIDNAPGMLVAALAEFGIRGIDLTRIESRPTR
TELGTYLFFVDCVGHIDDGVVAEALKALHRRCADVCYLGSWPAGLATGPTVSPPPPDEASRWLARLRAGKPDQASEPGGG
KL

Sequences:

>Translated_322_residues
MSVARIAYLGPEGTFTEAALLRMTAAGLVPDTGPDGLRRWPTESTPAALDAVRGGAADYACVPIENSIDGSVAPTLDNLA
IGSPLQVFAETTLDVEFNIVVKPGITAADIRTLAAFPVAAAQVRQWLAAHLAGAELRPAYSNADAARQVAYGQVDAAVTS
PLAATRWGLIALAAGIVDEPNARTRFVLVGMPGPPPARTGTDRTSAVLRIDNAPGMLVAALAEFGIRGIDLTRIESRPTR
TELGTYLFFVDCVGHIDDGVVAEALKALHRRCADVCYLGSWPAGLATGPTVSPPPPDEASRWLARLRAGKPDQASEPGGG
KL
>Mature_321_residues
SVARIAYLGPEGTFTEAALLRMTAAGLVPDTGPDGLRRWPTESTPAALDAVRGGAADYACVPIENSIDGSVAPTLDNLAI
GSPLQVFAETTLDVEFNIVVKPGITAADIRTLAAFPVAAAQVRQWLAAHLAGAELRPAYSNADAARQVAYGQVDAAVTSP
LAATRWGLIALAAGIVDEPNARTRFVLVGMPGPPPARTGTDRTSAVLRIDNAPGMLVAALAEFGIRGIDLTRIESRPTRT
ELGTYLFFVDCVGHIDDGVVAEALKALHRRCADVCYLGSWPAGLATGPTVSPPPPDEASRWLARLRAGKPDQASEPGGGK
L

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain

Homologues:

Organism=Escherichia coli, GI1788951, Length=284, Percent_Identity=25.3521126760563, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHEA_MYCLB (B8ZTU2)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002502814.1
- ProteinModelPortal:   B8ZTU2
- SMR:   B8ZTU2
- EnsemblBacteria:   EBMYCT00000085392
- GeneID:   7325817
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000015705
- HOGENOM:   HBG693866
- OMA:   CRKWLDA
- ProtClustDB:   PRK11898
- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528

Pfam domain/function: PF01842 ACT; PF00800 PDT

EC number: =4.2.1.51

Molecular weight: Translated: 33549; Mature: 33418

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00857 PREPHENATE_DEHYDR_1; PS00858 PREPHENATE_DEHYDR_2; PS51171 PREPHENATE_DEHYDR_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVARIAYLGPEGTFTEAALLRMTAAGLVPDTGPDGLRRWPTESTPAALDAVRGGAADYA
CCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCHHHHHHCCCCCCEE
CVPIENSIDGSVAPTLDNLAIGSPLQVFAETTLDVEFNIVVKPGITAADIRTLAAFPVAA
EEECCCCCCCCCCCCHHHHCCCCHHHHHHHEEEEEEEEEEECCCCCHHHHHHHHHHHHHH
AQVRQWLAAHLAGAELRPAYSNADAARQVAYGQVDAAVTSPLAATRWGLIALAAGIVDEP
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC
NARTRFVLVGMPGPPPARTGTDRTSAVLRIDNAPGMLVAALAEFGIRGIDLTRIESRPTR
CCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCH
TELGTYLFFVDCVGHIDDGVVAEALKALHRRCADVCYLGSWPAGLATGPTVSPPPPDEAS
HHHHHHHHEEEHHHCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCHHHH
RWLARLRAGKPDQASEPGGGKL
HHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVARIAYLGPEGTFTEAALLRMTAAGLVPDTGPDGLRRWPTESTPAALDAVRGGAADYA
CCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCHHHHHHCCCCCCEE
CVPIENSIDGSVAPTLDNLAIGSPLQVFAETTLDVEFNIVVKPGITAADIRTLAAFPVAA
EEECCCCCCCCCCCCHHHHCCCCHHHHHHHEEEEEEEEEEECCCCCHHHHHHHHHHHHHH
AQVRQWLAAHLAGAELRPAYSNADAARQVAYGQVDAAVTSPLAATRWGLIALAAGIVDEP
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC
NARTRFVLVGMPGPPPARTGTDRTSAVLRIDNAPGMLVAALAEFGIRGIDLTRIESRPTR
CCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCH
TELGTYLFFVDCVGHIDDGVVAEALKALHRRCADVCYLGSWPAGLATGPTVSPPPPDEAS
HHHHHHHHEEEHHHCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCHHHH
RWLARLRAGKPDQASEPGGGKL
HHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA